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Themicaine 2% Injection
Last updated on 26 Sep 2026 | 08:43 AM (IST)
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Introduction to Themicaine 2% Injection
Themicaine 2% Injection is a local anesthetic drug in the class ib antiarrhythmic agent category containing the active ingredient Lidocaine. It is a medication commonly used as a local anesthetic to numb a specific body area before minor surgical procedures, dental work, or diagnostic tests. It is administered as an injection, spray, or topical application to relieve pain and reduce discomfort during these procedures. It is also administered epidurally (into the epidural space of the spinal cord) to provide anesthesia and act as a pain reliever during childbirth. This drug is commonly used in emergencies to treat ventricular arrhythmias, particularly ventricular fibrillation.
Avoiding this product if you have a known allergy to this drug or any other local anesthetics is important. This drug should not be given if you have an abnormality of impulse propagation in the heart that causes decreased blood pressure and slow heart rate, such as complete heart block, because it can affect the electrical conduction in the heart and may exacerbate these conditions. Themicaine 2% Injection should not be administered if you have a condition of decreased blood volume called hypovolaemia. This condition can interfere with the distribution and effectiveness of the medication.
When Themicaine 2% Injection is combined with adrenaline (epinephrine), it should not be administered into a vein or used in areas with limited blood supply, such as fingers, toes, ears, nose, or penis, because it can lead to vasoconstriction throughout the body by causing inadequate blood flow to the organs. Inform your doctor about any pre-existing medical conditions, especially those related to the heart, liver, or kidneys. This medicine may require dose adjustments or close monitoring in individuals with certain medical conditions.
Uses of Themicaine 2% Injection
- Local anesthesia
Therapeutic Effects of Themicaine 2% Injection
Themicaine 2% Injection works by blocking nerve signals in the body, temporarily numbing the area where it is applied or injected. It inhibits the conduction of pain signals to the brain, providing local pain relief or anesthesia.
Interaction of Themicaine 2% Injection with other drugs
Inform your physician about any prescribed medications, over-the-counter medicines, and nutritional or vitamin supplements you have taken before the treatment. Certain medications may interact with Themicaine 2% Injection and cause undesirable side effects.
More Information about Themicaine 2% Injection
- Do not store above 25 °C.
- Keep out of sight and reach of pets and children.
How to consume Themicaine 2% Injection
Themicaine 2% Injection will be administered to you by a healthcare professional in a hospital setting. It is usually administered as an intravenous injection into a vein. Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.
Safety Advice for Themicaine 2% Injection
Breast Feeding
Consult your doctor before using this Themicaine 2% Injection if you are a breastfeeding mother.
Alcohol
It is unknown whether consuming alcohol after administering Themicaine 2% Injection is safe. Please speak with your physician.
Liver
It is unknown whether Themicaine 2% Injection is safe for patients with liver problems. Consult your doctor for more advice.
Lungs
It is unknown whether Themicaine 2% Injection is safe for patients with lung problems. Consult your doctor for more advice.
Driving
Driving vehicles or operating machinery after administering Themicaine 2% Injection is unsafe because it may cause numbness and impair your cognitive skills.
Pregnancy
Your doctor shall prescribe Themicaine 2% Injection only if necessary, and the benefits outweigh the risks.
Side Effects of Themicaine 2% Injection
Side Effects are unwanted symptoms caused by medicines. Although all medicines cause side effects, not everyone gets them.
Serious
- Severe allergic reactions
- Bluish discoloration of the skin
- Wheezing, itching, breathlessness, swelling of face, eyelids, mouth, etc.
- Changes in heart rate
- Low BP
Common
- Pain at the site of injection
- Temporary pain in the lower back, buttocks, and legs which resolves within a few days
- Numbness or tingling/paralysis of the legs
- Irregular bowel movements
- Tinnitus
- Loss of balance
- Dizziness
- Blurred vision
- Nausea
- Fear and anxiety
Word of Advice
It is highly advised to use this drug as directed and avoid exceeding the recommended dosage. When this drug is used in excessive amounts or if it enters the bloodstream, it can cause systemic effects such as dizziness, confusion, nervousness, tremors, and in severe cases, seizures or cardiac abnormalities. Always refer to the product packaging, and ask your physician for clarification if you have any doubts about the medicine. Keep Themicaine 2% Injection away from excessive moisture and heat, as they can degrade the medication. Store them in a cool, dry place.
FAQs about Themicaine 2% Injection
Q1.
Does Themicaine 2% Injection need to be refrigerated?
Most of these products don't require refrigeration. Generally, these formulations can be stored at room temperature, away from excessive heat, moisture, and direct sunlight. It's important to keep Themicaine 2% Injection and other medications out of reach for children and pets.
Q2.
Where should you not use Themicaine 2% Injection?
It's generally recommended to avoid administering Themicaine 2% Injection to infected or broken skin, as it may increase the chance of systemic absorption and potential side effects.
Q3.
Are there any side effects of Themicaine 2% Injection?
Common side effects of Themicaine 2% Injection may include temporary numbness, redness, itching, or a burning sensation at the application site. In rare cases, systemic side effects such as dizziness, confusion, slowed heart rate, or allergic reactions may occur. If you experience any side effects, seeking medical attention is important.
Q4.
Who should not use Themicaine 2% Injection?
Themicaine 2% Injection should be used with caution or avoided altogether in individuals who have a known allergy or hypersensitivity to this drug or other local anesthetics.
Q5.
What is Themicaine 2% Injection used for?
Themicaine 2% Injection is a local anesthetic medication commonly used to numb an area of the body for various medical procedures or relieve pain or discomfort from skin conditions, providing temporary relief for minor burns, sunburns, insect bites, or rashes.
Q6.
How Themicaine 2% Injection is administered?
Themicaine 2% Injection will be administered to you by a healthcare professional in a hospital setting. It is usually administered as an intravenous injection into a vein. Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.
Fact Box of Themicaine 2% Injection
Molecule Name: Lidocaine | Therapeutic class: Local Anaesthetics |
Pharmacological class: Class Ib antiarrhythmic agent | Indications: Local Anaesthesia |
References
- Mercury Pharmaceuticals Ltd, Electronic medicines compendium (EMC), [ Revised on May 2021] [ Accessed on 31st May 2023], https://www.medicines.org.uk/emc/files/pil.4781.pdf/
- Scilex Pharmaceuticals Inc, US Food and Drug Administration, [ Revised on Nov 2018] [Accessed on 31st May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/207962s001lbl.pdf
- Mercury Pharmaceuticals (Ireland) Ltd, [Revised on Apr 2016] [Accessed on 31st May 2023], https://www.hpra.ie/img/uploaded/swedocuments/2143491.PA0073_112_002.16cdbc15-75aa-42f5-b8ae-06ec698f0bd0.000001Lidocaine Injection%20Hydrochloride%201%20PIL.170524.pdf
- Kenneth Drasner, Local Anesthetics, Lange's Basic and Clinical Pharmacology, 14th Edition, 2018, 459-473.
- KD Tripathi, Local Anaesthetics, Essentials of Medical Pharmacology, 8th Edition, 2019, 386-398.
Disclaimer
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Author Details
Written By
Dr. B. Deiva
Pharm D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 26 Sep 2026 | 08:43 AM (IST)
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