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Themidol 50mg Injection
Last updated on 31 Mar 2026 | 09:31 AM (IST)
₹14
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1 AMPOULE(s) OF 2ML
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₹14
MRP: ₹21.93
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Introduction to Themidol 50mg Injection
Themidol 50mg injection is a drug belonging to the class of tyrosine kinase inhibitors, containing the active ingredient Tramadol. It is used to treat moderate to severe pain, such as that caused by surgery, or chronic conditions like arthritis. This injection can also be used in cancer patients to manage pain caused by cancer or cancer treatments.
If you experience any symptoms of an allergic reaction, such as difficulty breathing, swelling of the face or throat, or a severe rash, consult your doctor immediately. This injection is not recommended for long-term use or for the treatment of mild pain. It should be used with caution in patients with a history of substance abuse, respiratory depression, or liver or kidney disease. This drug can be habit-forming and should be avoided in patients with a history of substance abuse. It can cause withdrawal symptoms when stopped suddenly or when the dose is reduced too quickly. Patients should be gradually tapered off this drug to minimize the risk of withdrawal symptoms.
During the treatment, your doctor may periodically monitor your respiratory function, blood pressure, liver function, and mental status. Doctors may also adjust the dose, switch to a different medication, or alter the treatment plan as needed to reduce the complications and side effects. Consult your doctor before using this medication if you are pregnant or plan to have a baby. This injection is unsafe to use during pregnancy as it causes harm to an unborn fetus. Your healthcare practitioner will conduct a pregnancy test before you start treatment with this injection. Breastfeeding should be avoided during the treatment with this drug as it may pass into breast milk in small amounts. This drug can cause sleep-related breathing disorders such as sleep apnoea (breathing pauses during sleep) and sleep-related hypoxemia (low oxygen level in the blood). The symptoms can include night awakening due to shortness of breath, difficulties maintaining sleep, or excessive drowsiness during the day. Inform your doctor if any of these problems develop while you are using this medicine.
Uses of Themidol 50mg Injection
- Treatment of moderate to severe pain
- Post-operative pain
Therapeutic Effects of Themidol 50mg Injection
Themidol 50mg injection works by binding to specific receptors in the brain and spinal cord that are involved in transmitting pain signals, thereby reducing the amount of pain signals that are sent to the brain.
Interaction of Themidol 50mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Themidol 50mg injection and reduce effectiveness by causing undesirable side effects.
More Information about Themidol 50mg Injection
- Store Themidol 50mg injection in the original package at room temperature (20°C to 25°C).
- Keep it out of reach from children.
How to consume Themidol 50mg Injection
Themidol 50mg injection should only be administered by a trained doctor or nurse. It will be given as a slow injection into a vein or muscle. Your doctor will decide the dose and duration of the treatment based on your disease severity and other factors. Do not self-administer the medication.
Safety Advice for Themidol 50mg Injection
Breast Feeding
Breastfeeding is not recommended in patients taking Themidol 50mg injection because the medicine passes into the breast milk in small amounts and may harm your baby.
Alcohol
Consuming alcohol may affect the effectiveness of Themidol 50mg injection. Stop consuming alcohol if you are taking this medicine.
Liver
Inform your doctor if you have any liver problems before taking Themidol 50mg injection. Regular monitoring of liver function tests is recommended.
Lungs
Inform your doctor if you have any lung problems before taking Themidol 50mg injection.
Driving
It is unsafe to drive vehicles or operate heavy machinery after taking Themidol 50mg Injections, it may cause dizziness and impair your concentration.
Pregnancy
Themidol 50mg injection is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Side Effects of Themidol 50mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Allergic reactions
- Breathing troubles during sleep
Common
- Tiredness
- Sweating
- Vomiting
- Constipation
- Dry mouth
- Headache
- Sleepiness, low energy, drowsiness
- Nausea
Word of Advice
It is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment. Discuss effective non-hormonal contraceptive methods with your healthcare provider and use them during this treatment and continue for at least six months after the last dose. Themidol 50mg injection passes into the breast milk. Hence, it is not recommended to breastfeed during this treatment. This injection might cause breathing difficulty and problems with sleeping. Hence it is advisable to avoid driving or operating machines during this treatment. Before starting this treatment, inform your doctor if you are taking any prescription medicines, over-the-counter medicines, vitamins, or herbal supplements.
FAQs about Themidol 50mg Injection
Q1.
Can I drink alcohol while taking Themidol 50mg injection?
It is generally recommended to avoid drinking alcohol while taking Themidol 50mg injection, as alcohol can increase the risk of liver damage.
Q2.
Why is Themidol 50mg injection IV given slowly?
When this drug is given intravenously (IV), it can cause a sudden drop in blood pressure, which can be potentially dangerous. Therefore, it is recommended to administer Themidol 50mg injection IV slowly over a period of 15-30 minutes.
Q3.
When should Themidol 50mg injection be avoided?
Themidol 50mg injection should be avoided in patients with a history of substance abuse since it is a habit-forming drug.
Q4.
What happens when Themidol 50mg injection is taken in higher doses?
Respiratory depression is more likely to occur in patients who take higher doses of Themidol 50mg injection, have pre-existing respiratory disorders, or take other medications that depress the respiratory system.
Q5.
Does Themidol 50mg injection affect urine flow?
Yes, Themidol 50mg injection can affect urine flow in some patients. This drug can cause urinary retention, which is a condition where the bladder is unable to empty completely, leading to a reduced flow of urine. This occurs because this drug can interfere with the signals that the nervous system sends to the bladder to initiate urination.
Fact Box of Themidol 50mg Injection
Molecule name: Tramadol | Therapeutic class: Analgesics |
Pharmacological class: Opioid agonist | Indications: 1.Treatment of moderate to severe pain 2. Post-operative pain |
References
- Hameln pharma ltd., Electronic Medicines Compendium (EMC), [Revised on Jul 2021] [Accessed on 26 April 2023], https://www.medicines.org.uk/emc/files/pil.3420.pdf
- Seqirus Pty Ltd, [Revised on 27th Jul 2021] [Accessed on 26 April 2023], https://labeling.seqirus.com/PI/AU/Tramal/EN/Tramal-Product-Information.pdf
- Package leaflet: Information for the user Tradol 50 mg/ml Solution for injection or infusion- HPRA. Available at: https://www.hpra.ie/img/uploaded/swedocuments/bc6d3cd9-99f2-4e3d-92e6-c8aa8c6bb9cc.pdf [Accessed on 26 April 2023].
- Ahmed A. Negm, Daniel E. Furst, NSAIDs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 642-666.
- Opioid Analgesics and Antagonists, Essentials of Medical Pharmacology, 8th Edition, 2019, 497-514.
Disclaimer
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Author Details
Written By
Dr. Bhairavi S
Pharm. D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:31 AM (IST)
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