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Thyrogen Kit 0.9mg Injection
Salt Composition : Thyrotropin Alfa
Manufacturer : SANOFI INDIA LTD
Origin of Medicine : France
Introduction to Thyrogen Kit 0.9mg Injection
Thyrogen kit 0.9mg injection contains the active constituent Thyrotropin Alfa. It is a recombinant of thyroid stimulating hormone that belongs to the class of medications called diagnostic agents. It is used in people who have had their thyroid gland removed and are taking thyroid hormones to detect certain types of thyroid cancer. It is also used with radioiodine treatment to eliminate the thyroid tissue which is left over after surgical removal of the thyroid gland in patients who do not have secondary cancer growths and in those who are taking thyroid hormone.
Do not take Thyrogen kit 0.9mg injection if you are allergic to Thyrotropin Alfa or any of the other ingredients and if you are pregnant. Inform your physician if you have heart, kidney, or liver disease before initiating the treatment. Due to limited data, the medicine's safety in children is not well established. No special precautions are needed for elderly patients taking this medicine. Do not breastfeed or become pregnant during the treatment with this medicine. Inform your doctor if you are pregnant, suspecting, or planning for pregnancy before receiving this medicine.
Uses of Thyrogen Kit 0.9mg Injection
- Detects certain types of thyroid cancer removed after therapy.
- Eliminate leftover thyroid tissue after surgery in combination with radioiodine treatment.
Therapeutic Effects of Thyrogen Kit 0.9mg Injection
Thyrogen kit 0.9mg injection is a pituitary hormone that stimulates the thyroid gland to produce thyroid hormone. The binding of this injection to TSH receptors on normal thyroid epithelial cells or well-differentiated thyroid cancer tissue stimulates iodine uptake and organification and synthesis and secretion of thyroglobulin (Tg), triiodothyronine (T3), and thyroxine (T4). One of the effects is that it stimulates any remaining thyroid tissue to take up iodine which is important for radioiodine imaging. It also stimulates the production of thyroglobulin and thyroid hormones if there is any thyroid tissue left. These hormones can be measured in your blood.
Interaction of Thyrogen Kit 0.9mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Thyrogen kit 0.9mg injection and reduce its effectiveness by causing undesirable side effects. Inform your doctor if you are using birth control pills.
More Information about Thyrogen Kit 0.9mg Injection
- Store in a refrigerator (2°C - 8°C)
- Protect the medicine from light and excessive moisture.
- Keep the medicine out of reach of children and pets
- If you missed the dosing schedule, inform your healthcare professional immediately and reschedule.
How to consume Thyrogen Kit 0.9mg Injection
Thyrogen kit 0.9mg injection will be administered to you by a doctor or other healthcare professional in a hospital setting trained in cancer chemotherapy. Your doctor will decide the dose, route of administration, and duration of the therapy based on your disease status, severity, and other factors such as body weight, other disease conditions, and age. This medicine will be given intramuscularly. Do not self-administer the injection.
Safety Advices for Thyrogen Kit 0.9mg Injection
Do not take Thyrogen kit 0.9mg injection if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment.
Breastfeeding is not recommended in patients taking Thyrogen kit 0.9mg injection because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
It is unknown whether Thyrogen kit 0.9mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
There is limited information available on the use of Thyrogen kit 0.9mg injection in patients with liver disease. Please consult your doctor if you have any liver diseases.
It is unknown whether it is safe to consume alcohol with Thyrogen kit 0.9mg injection. Inform your physician if you are a chronic drinker.
Thyrogen kit 0.9mg injection may affect the ability to drive and operate machinery. Avoid taking the medicine if you face any of these symptoms.
Side Effects of Thyrogen Kit 0.9mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
- Severe hypersensitivity reaction
- CNS problems
Word of Advice
This medicine will be administered to you by a healthcare professional, and you will be monitored throughout the treatment. The injection will be given intramuscularly (into your muscles). Drink extra fluids before treatment with this medicine. You may receive additional medication before starting the treatment with this medicine. Inform your physician if you are using birth control pills. This medicine may be given together with radioiodine. You will be exposed to radiation while receiving radioiodine. Talk with your doctor about precautions that you should take for yourself and for the people around you.
Q 1. Can a patient with kidney problems take Thyrogen kit 0.9mg injection?
Thyrogen kit 0.9mg injection should be cautiously administered in patients with kidney problems that require dialysis. Your doctor will decide the dose of the medicine if you have kidney disease.
Q 2. What are the common side effects of Thyrogen kit 0.9mg injection?
The most common side effects of the injection are nausea, vomiting, and headache.
Q 3. Are there any special dietary instructions I should follow while taking Thyrogen kit 0.9mg injection?
Inform your doctor if you have any heart diseases or any history of heart problems, liver and kidney diseases before initiating the treatment. Drink more fluids before receiving this injection.
Q 4. How is Thyrogen kit 0.9mg injection administered?
After reconstitution, the injection will be given as a shot into one of your muscles (intramuscularly). The injection will be given by a healthcare professional trained in administering cancer chemotherapy.
Q 5. What organ does Thyrogen kit 0.9mg injection target?
Thyrotrophin alfa is another name for Thyroid Stimulating Hormone (TSH), which is so called 'thyroid' and refers to the thyroid gland.
Fact Box of Thyrogen Kit 0.9mg Injection
Molecule name: Thyrotropin Alfa
Therapeutic class: Diagnostic agent
Pharmacological class: Thyroid stimulating hormone
1. Detects certain types of thyroid cancer removed after therapy.
2. Eliminate leftover thyroid tissue after surgery in combination with radioiodine treatment.
- Thyrogen 0.9 mg powder for solution for injection - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published September 2022. Accessed May 5, 2023. http://www.medicines.org.uk/emc/product/235/smpc
- Genzyme Corporation, US Food and Drug Administration, [ Accessed on may 5, 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020898s051lbl.pdf
- Ujjal Mallick et al; Ablation with low-dose radioiodine and thyrotropin alfa in thyroid cancer; The New England Journal of Medicine; Published on May 2012; Accessed on 05/05/2023; https://pubmed.ncbi.nlm.nih.gov/22551128/
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