• Detects certain types of thyroid cancer removed after therapy.
• Eliminate leftover thyroid tissue after surgery in combination with radioiodine treatment.

Thyrogen kit 0.9mg injection is a pituitary hormone that stimulates the thyroid gland to produce thyroid hormone. The binding of this injection to TSH receptors on normal thyroid epithelial cells or well-differentiated thyroid cancer tissue stimulates iodine uptake and organification and synthesis and secretion of thyroglobulin (Tg), triiodothyronine (T3), and thyroxine (T4).  One of the effects is that it stimulates any remaining thyroid tissue to take up iodine which is important for radioiodine imaging. It also stimulates the production of thyroglobulin and thyroid hormones if there is any thyroid tissue left. These hormones can be measured in your blood.

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Thyrogen kit 0.9mg injection and reduce its effectiveness by causing undesirable side effects. Inform your doctor if you are using birth control pills. 

• Store in a refrigerator (2°C - 8°C)
• Protect the medicine from light and excessive moisture.
• Keep the medicine out of reach of children and pets
• If you missed the dosing schedule, inform your healthcare professional immediately and reschedule.

Thyrogen kit 0.9mg injection will be administered to you by a doctor or other healthcare professional in a hospital setting trained in cancer chemotherapy. Your doctor will decide the dose, route of administration, and duration of the therapy based on your disease status, severity, and other factors such as body weight, other disease conditions, and age. This medicine will be given intramuscularly. Do not self-administer the injection. 

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. 

Common 

• Nausea
• Vomiting
• Headache 

Serious  

• Hyperthyroidism
• Severe hypersensitivity reaction
• CNS problems

This medicine will be administered to you by a healthcare professional, and you will be monitored throughout the treatment. The injection will be given intramuscularly (into your muscles). Drink extra fluids before treatment with this medicine. You may receive additional medication before starting the treatment with this medicine. Inform your physician if you are using birth control pills. This medicine may be given together with radioiodine. You will be exposed to radiation while receiving radioiodine. Talk with your doctor about precautions that you should take for yourself and for the people around you.

1. Thyrogen 0.9 mg powder for solution for injection - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published September 2022. Accessed May 5, 2023. http://www.medicines.org.uk/emc/product/235/smpc
2. Genzyme Corporation, US Food and Drug Administration, [ Accessed on may 5, 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020898s051lbl.pdf
3. Ujjal Mallick et al; Ablation with low-dose radioiodine and thyrotropin alfa in thyroid cancer; The New England Journal of Medicine; Published on May 2012; Accessed on 05/05/2023; https://pubmed.ncbi.nlm.nih.gov/22551128/