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Tipanat 20mg Tablet

Prescription Required

Salt Composition : Trifluridine And Tipiracil

Manufacturer : NATCO PHARMA LTD

Origin of Medicine : India

MRP: 10000
Price :8200
You Save :1800 (18%)

20 Tablet(s) In A Bottle

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Introduction to Tipanat 20mg Tablet

Tipanat 20mg tablet is an anticancer medication containing the two active constituents Trifluridine and Tipiracil. It is used to treat adults with colon and rectum cancer when it reaches the metastases stage (cancer has spread to other parts of the body) and when other treatments are unsuitable. Trifluridine inhibits the growth of cancer cells, whereas Tipiracil stops the Trifluridine from being broken down and helps it to work longer. Cancer is a condition in which the cells multiply uncontrolled and abnormally. This medicine is not recommended for adolescents and children under 18.

Do not consume this medicine if you are allergic to Tipanat 20mg or other ingredients. Before starting the treatment, notify your doctor if you have a problem with your kidney or liver and are lactose intolerant. This treatment may lead to side effects such as neutropenia (lowered WBC), anemia (reduced number of RBC), and gastrointestinal problems. Report your doctor if you experience any side effects or symptoms. Dose adjustment is needed in patients with a kidney condition. Inform your doctor if you are preganat or planning to get pregnant; this medicine may harm the unborn baby, so use contraception by both males and females during and after the treatment for six months. 

Uses of Tipanat 20mg Tablet

  • Metastatic colorectal cancer

Therapeutic Effects of Tipanat 20mg Tablet

Trifluridine interferes with the DNA synthesis of cancer cells and inhibits the growth of cancer cells. Tipiracil stops the body from breaking down Trifluridine and increases its exposure.

Interaction of Tipanat 20mg Tablet with other drugs

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications, such as Zidovudine and others, may interact with Tipanat 20mg and cause undesirable side effects. 

More Information about Tipanat 20mg Tablet

  • Keep Tipanat 20mg tablets out of sight and reach of children.
  • Store at room temperature (20°C - 25°C).

How to consume Tipanat 20mg Tablet

Take Tipanat 20mg as advised by your physician. Usually, this medicine will be taken as a whole with a glass of water. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking this medicine if your doctor advises you to stop.

Safety Advices for Tipanat 20mg Tablet

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Tipanat 20mg is unsafe during pregnancy as it may harm the unborn baby. Report to your doctor if you are pregnant or think you may be pregnant or planning for the pregnancy before starting the treatment. Use effective contraception. 

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Breast Feeding


Taking Tipanat 20mg while breastfeeding may be unsafe because it may affect the child. Do not breastfeed for at least four months after the treatment. Therefore, talk with your doctor to get more information. 

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It is unknown whether Tipanat 20mg is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

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Inform your physician if you have liver problems because Tipanat 20mg should be used cautiously with this condition.

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It is unknown whether consuming alcohol while taking a Tipanat 20mg tablet is safe. Please speak with your physician.

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While taking Tipanat 20mg, driving or using machines is unsafe because it may affect your ability to concentrate and react. Talk to your doctor for more information. 

Side Effects of Tipanat 20mg Tablet

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.


  • Low white blood cell count (fever, chills)
  • Anemia (shortness of breath, tiredness)
  • Diarrhea, vomiting, abdominal pain
  • Unusual bleeding or bruising
  • Severe gastrointestinal problem


  • Lack of appetite
  • Nausea
  • Hair loss
  • Weight loss
  • Changes in taste
  • Constipation
  • Swelling in hands or feet or mucous membranes
  • Mouth pain
  • Itchy dry skin
  • A lower level of albumin
  • Increased bilirubin
  • Increase liver enzymes

Word of Advice

Notify your doctor if you are intolerant to sugar, as this medicine contains lactose. Your doctor may adjust the dosage if you are an inpatient with a kidney condition. Tipanat 20mg come in two strengths, usually given twice a day. Your doctor may take a blood test before each test. Discuss the effective contraception method with your doctor.  


Q 1. Who should not take Tipanat 20mg?

Tipanat 20mg should not be taken by individuals allergic to any of its components. It should also be avoided by individuals with severely decreased bone marrow function (reduction in blood count), severe infections, or severe renal or hepatic impairment.

Q 2. Can Tipanat 20mg be taken with other medications?

Tipanat 20mg may interact with other medications, so it is important to inform your doctor of all the medications, vitamins, and supplements you are currently taking.

Q 3. Can Tipanat 20mg affect our immune system?

Tipanat 20mg is not known to affect the immune system directly, but it can indirectly affect it by reducing the number of white blood cells (WBC) in the body. This can increase the risk of infections.

Q 4. What should I do if I miss a dose of Tipanat 20mg?

If you miss a dose of Tipanat 20mg, take it as soon as you remember. Don't double dose to make up for a missed one.

Q 5. At what condition is dose adjustment needed for Tipanat 20mg?

If you are a patient with kidney disease, inform your doctor before starting the treatment because adjustment is needed in kidney-conditioned patients.

Fact Box of Tipanat 20mg Tablet

Molecule Name: Trifluridine and Tipiracil

Therapeutic class: Antimetabolites

Pharmacological class: Thymidylate Synthetase Inhibitors 

Indications: Metastatic colorectal cancer


  1. Les Laboratories Servier, Electronic medicines compendium (EMC), [Revised on Dec 2020] [Accessed on 25th April 2023],
  2. Taiho Oncology, US Food, and Drug Administration, [Revised on Feb 2019] [ Accessed on 25th April 2023],
  3. Celeste B Burness, Sean T Duggan; Trifluridine/Tipiracil: A Review in Metastatic Colorectal Cancer; Drugs; Published on Sep 2016; Accessed on 03/03/2022;


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