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Twinrab 600IU Injection
Salt Composition : Docaravimab,miromavimab
Manufacturer : ZYDUS CADILA
Origin of Medicine : India
1 Vial(s) Of 1ml
Introduction to Twinrab 600iu Injection
Twinrab 600IU injection is a combination medication containing docaravimab and miromavimab as active components belonging to the monoclonal antibodies (mAb) group. It is indicated for post-exposure prophylaxis to prevent rabies infection in people exposed to the virus. It is given in combination with the rabies vaccine.
Rabies is a viral disease that causes inflammation of the brain. It can spread to pets and people if they are bitten or scratched by virus-carrying animals such as dogs, bats, etc. Even though it is a fatal disease, it is preventable.
Before initiating the treatment, consult your healthcare professional and disclose any known allergies to similar products. During and after the treatment, keenly monitor for any adverse reactions. This injection is safe to use in children. Talk to your physician if you are pregnant or breastfeeding before taking twinrab 600IU injection.
Uses of Twinrab 600iu Injection
- Prevent rabies infection
Therapeutic Effects of Twinrab 600iu Injection
Twinrab 600IU injection contains two antibodies: docaravimab and miromavimab. These antibodies bind to the rabies virus and prevent it from entering and infecting nerve cells and other cells in the body. This interruption of the virus's ability to replicate and spread within the body is crucial for halting the progression of rabies infection.
Interaction of Twinrab 600iu Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with twinrab 600IU injection and cause undesirable side effects.
More Information about Twinrab 600iu Injection
- Keep docaravimab + miromavimab Injection out of sight and reach of children.
- Store between 2°C and 8°C.
How to consume Twinrab 600iu Injection
Twinrab 600IU injection is given only in a hospital set up by a trained healthcare provider. It will be given to you as an injection into your muscle (intramuscularly) for adults in the arm and children in the thigh. Your doctor will decide your most apt dosage based on age, body weight, and physical circumstances.
Safety Advices for Twinrab 600iu Injection
The safety and efficacy of this injection in pregnant women is not yet established. You need to tell your doctor if you are pregnant or planning to get pregnant before taking twinrab 600IU injection.
The safety and efficacy of this injection in breastfeeding women are not yet established. You need to inform your doctor if you are breastfeeding before taking twinrab 600IU injection.
The safety and efficacy of this injection in lung patients have yet to be established. Inform your doctor if you have any lung disorder before taking twinrab 600IU injection.
The safety and efficacy of this injection in pregnant women is not yet established. Inform your doctor if you have any liver disorder before taking twinrab 600IU injection.
It is unknown whether it is safe to drink alcohol while taking twinrab 600IU injection. Consult Your doctor for more advice.
It is unknown whether twinrab 600IU injection will affect your driving ability. Contact your doctor for more advice.
Side Effects of Twinrab 600iu Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
- Allergic Reactions
- Injection site pain
- Headache, dizziness
Word of Advice
For those prescribed twinrab 600IU injection, it is crucial to prioritize safety through open communication with your healthcare provider. Adhering strictly to the prescribed dosage and schedule is paramount. If this injection is combined with a rabies vaccine, ensure compliance with the recommended vaccination schedule. Attend all scheduled follow-up appointments for proper monitoring.
Familiarize yourself with the signs of severe reactions and seek immediate medical attention if necessary. Communicate promptly with your healthcare provider regarding any changes in your health status. If you are pregnant or planning to breastfeed, discuss your plans with your healthcare provider. Always seek personalized advice from healthcare professionals to ensure your safety during treatment.
Q 1. What is twinrab 600IU injection used for?
Twinrab 600IU injection is used in the treatment of Rabies. It is indicated for post-exposure prophylaxis to prevent rabies infection in people exposed to the virus. It is given in combination with the rabies vaccine.
Q 2. How long does the immunity provided by twinrab 600IU injection last?
The immunity provided by twinrab 600IU injection is not lifelong. It offers protection for a limited period. Your healthcare provider will guide you on the need for booster doses or additional vaccinations to maintain immunity.
Q 3. Is it safe to drive while undergoing treatment with twinrab 600IU injection?
The impact of twinrab 600IU injection on driving ability is unknown. It's advisable to consult your doctor for personalized advice. Until you know how the medication affects you, it's wise to exercise caution while driving or operating heavy machinery.
Q 4. What should I do if I miss a scheduled injection of twinrab 600IU injection?
Itis important to adhere to the prescribed dosage and schedule during the treatment with twinrab 600IU injection . If you miss a scheduled injection, contact your healthcare provider immediately for guidance. They will provide instructions on whether a makeup dose is needed and the appropriate course of action.
Q 5. Are there specific signs of severe reactions that I should watch for during the treatment with twinrab 600IU injection?
Yes, it is essential to be aware of signs of severe reactions, especially allergies. These may include difficulty breathing, swelling, or severe injection site pain. If you experience any of these symptoms or other concerning issues during the treatment with twinrab 600IU injection, seek immediate medical attention and inform your healthcare provider promptly.
Fact Box of Twinrab 600iu Injection
Molecule Name: Docaravimab + miromavimab
Therapeutic class: Antivirals, Immunomodulators
Pharmacological class: Anti-rabies monoclonal antibody (Rabimabs)
- Zydus; the U.S. Food And Drug Administration (FDA) [Accessed on 14/08/202] https://www.fda.gov/media/106517/download
- Kevinkumar Kansagra et al. A Phase 3, Randomised, Open-Label, Non-inferiority Trial Evaluating Anti-Rabies Monoclonal Antibody Cocktail (TwinrabTM) Against Human Rabies Immunoglobulin (HRIG); Clinical Infectious Diseases; Published on 17/06/2020; Accessed on 14/08/2021; https://pubmed.ncbi.nlm.nih.gov/32556113/
- De Melo GD et al., A combination of two human monoclonal antibodies cures symptomatic rabies; EMBO Mol Med; Published on 06/11/2020; Accessed on 13/11/2023 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645379/
- Anti-rabies virus monoclonal antibodies, World Health Organisation (WHO), https://list.essentialmeds.org/recommendations/1220/print?format=pdf
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