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TYSABRI 300MG INJECTION_1
TYSABRI 300MG INJECTION_1
22% Off

Tysabri 300mg Injection

Prescription Required

cold-chain

Salt Composition : Natalizumab

Manufacturer : BIOGEN IDEC BIOTECH INDIA PVT LTD

Origin of Medicine : United States of America

MRP: ₹108702
Price : ₹84537
You Save : ₹24165 (22%)

1 Vial(s)

Prepaid Only. Non-Returnable

PAP Information :    Buy 1, get 1 Free. Contact us for latest updates.


Patient Assistance Programs
Know About PAP

Program Overview: BIOGEN IDEC BIOTECH INDIA PVT LTD, Patient Assistance Program (PAP) is dedicated to helping patients in need of Tysabri 300mg Injection. The program aims to provide eligible patients with access to the medication at a more affordable cost.

Program Benefits: Purchase 1 vial of Tysabri 300mg Injection, and you will receive 1 free additional vial. Therefore, if eligible, you will have to pay only Rs.84,537 for two vials, which is Rs.42,269 per vial.

With MrMed's MRP discount of Rs. 24,165 per vial and Biogen’s PAP program, the overall savings is over 1.3 lakhs rupees.

Contact us for the latest updates on this exclusive offer.

Eligibility Criteria: To qualify for the Tysabri Patient Assistance Program (PAP), you must meet specific criteria, including having a valid prescription for Natalizumab 300mg from a medical oncologist and being an Indian patient with a valid identity card. Eligibility is determined based on the diagnosed condition and program-specific requirements.

Contact Information: If you have any questions or need assistance with the application process, our dedicated patient support team is here to help. You can reach us by phone at 89391 69999 or email us at [email protected].

Please note that MrMed is not involved in the PAP program. They offer free consultations to patients to provide information about the program. Patients eligible for the PAP program by Fresenius can avail of it without having to purchase the medication from MrMed.

Patient Assistance Programs

Program Overview: BIOGEN IDEC BIOTECH INDIA PVT LTD, Patient Assistance Program (PAP) is dedicated to helping patients in need of Tysabri 300mg Injection. The program aims to provide eligible patients with access to the medication at a more affordable cost.

Program Benefits: Purchase 1 vial of Tysabri 300mg Injection, and you will receive 1 free additional vial. Therefore, if eligible, you will have to pay only Rs.84,537 for two vials, which is Rs.42,269 per vial.

With MrMed's MRP discount of Rs. 24,165 per vial and Biogen’s PAP program, the overall savings is over 1.3 lakhs rupees.

Contact us for the latest updates on this exclusive offer.

Eligibility Criteria: To qualify for the Tysabri Patient Assistance Program (PAP), you must meet specific criteria, including having a valid prescription for Natalizumab 300mg from a medical oncologist and being an Indian patient with a valid identity card. Eligibility is determined based on the diagnosed condition and program-specific requirements.

Contact Information: If you have any questions or need assistance with the application process, our dedicated patient support team is here to help. You can reach us by phone at 89391 69999 or email us at [email protected].

Please note that MrMed is not involved in the PAP program. They offer free consultations to patients to provide information about the program. Patients eligible for the PAP program by Fresenius can avail of it without having to purchase the medication from MrMed.

Introduction to Tysabri 300mg Injection

Tysabri 300mg injection contains an active component such as Natalizumab. This medication is a monoclonal antibody medication used to treat multiple sclerosis (MS) and Crohn's disease. Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system, causing communication problems between the brain and the rest of the body. Crohn's disease is a chronic inflammatory condition affecting the gastrointestinal tract. This medication-targeted mechanism of action reduces inflammation by blocking specific immune cell movement, thereby mitigating potential damage to the central nervous system in MS or reducing inflammation in the gut in Crohn's disease. By effectively managing disease activity, Tysabri 300mg injection can improve patients' overall quality of life by reducing symptoms, decreasing the frequency of relapses, and potentially delaying disability progression.

Tysabri 300mg injection can cause hypersensitivity reactions in some individuals. Patients with a history of hypersensitivity to this medicine or its components should avoid its use, and individuals at higher risk need screening. This medication is contraindicated in patients with a history of progressive multifocal leukoencephalopathy (PML) or who are positive for the JC virus, as they are at a higher risk of developing PML during treatment. It should not be used in patients with active infections, especially serious or opportunistic infections. Its safety and effectiveness in pediatric patients (children and adolescents) have not been fully established. Therefore, its use in this population is generally not recommended.


Uses of Tysabri 300mg Injection

Tysabri 300mg injection is used to treat the following:

  • Multiple sclerosis (MS)
  • Crohn's disease.

Therapeutic Effects of Tysabri 300mg Injection

Tysabri 300mg injection is a monoclonal antibody that works by targeting a protein called α4-integrin on certain immune cells. By binding to α4-integrin, it prevents these immune cells from crossing the blood-brain barrier in multiple sclerosis or migrating into the gut lining in Crohn's disease. This action reduces inflammation and helps protect the central nervous system in MS, leading to fewer relapses and slowed disease progression. Overall, its mechanism of action modulates the immune response, providing therapeutic benefits in treating multiple sclerosis and Crohn's disease.


Interaction of Tysabri 300mg Injection with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Tysabri 300mg injection, reducing effectiveness by causing undesirable side effects. 


More Information about Tysabri 300mg Injection

  • Store at room temperature, between  2°C to 8°C (36°F to 46°F).
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Tysabri 300mg Injection

Tysabri 300mg injection should be taken exactly as prescribed by a healthcare professional. The route of administration for this medication is intravenous (IV) infusion. The medication is delivered directly into the bloodstream through a vein. It is not available in oral form or as a subcutaneous injection.


Safety Advices for Tysabri 300mg Injection

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Pregnancy

  

Pregnant women or those planning to become pregnant should discuss all potential risks and benefits of using Tysabri 300mg injection with their healthcare provider. They will assess the risks and benefits of continuing the medication during pregnancy and discuss alternative treatments if necessary.

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Breast Feeding

  

The safety of Tysabri 300mg injection during breastfeeding is not fully established, and  the healthcare provider will provide personalized advice to make an informed decision regarding the use of the medication during this period, considering the well-being of both the mother and the baby. 

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Lungs

  

Patients taking Tysabri 300mg injection should promptly report any respiratory symptoms to their healthcare provider and adhere to prescribed treatments to manage their underlying condition effectively. 

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Liver

  

If you have liver-related medical conditions, such as liver disease or liver dysfunction, it is crucial to inform your healthcare provider about your condition before starting Tysabri 300mg injection or any other medication. 

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Alcohol

  

Limit alcohol consumption and consult your healthcare provider for personalized advice regarding alcohol use while taking Tysabri 300mg injection.

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Driving

  

During treatment with Tysabri 300mg injection, patients should exercise caution when driving, as the medication may cause dizziness, fatigue, or other central nervous system-related side effects.


Side Effects of Tysabri 300mg Injection

Tysabri 300mg injection causes some side effects like all medications, although not everyone will experience them. 

Serious:

  • Progressive multifocal leukoencephalopathy (PML)
  • Infusion reactions
  • Liver damage
  • Infections
  • Hypersensitivity

Common:

  • Headache
  • Fatigue
  • Nausea
  • Upper respiratory tract infections (common cold)
  • Urinary tract infections

Word of Advice

For Tysabri 300mg injection safe use close monitoring for signs of progressive multifocal leukoencephalopathy (PML), a rare but serious brain infection, as well as hypersensitivity reactions during or after infusion. Regular liver function tests should be performed to detect any liver damage. Patients should be vigilant for signs of infections, and concomitant use with other immunomodulatory medications should be carefully considered. Prior screening for hepatitis B virus (HBV) is recommended, and live vaccines should not be administered during treatment. Pregnant or breastfeeding individuals should consult their healthcare provider before starting or continuing this medication. It is essential to discuss all medical conditions and medications with the healthcare provider to ensure the safe and appropriate use of these medications and to address any potential risks.


FAQs

Q 1. Can I receive other vaccines while on Tysabri 300mg injection?

Discuss vaccination plans with your healthcare provider. Some live vaccines may not be recommended while on Tysabri 300mg injection due to potential interactions.

Q 2. What should I do if I miss a dose of Tysabri 300mg injection?

Contact your healthcare provider to reschedule the missed dose. Do not double the dose to make up for the missed one.

Q 3. Can I travel while on Tysabri 300mg injection treatment?

Yes, you can travel while on Tysabri 300mg injection treatment. However, ensure you have access to medical facilities in an emergency, and inform your healthcare provider of your travel plans.

Q 4. Is it safe to stop Tysabri 300mg injection abruptly?

Abruptly stopping Tysabri 300mg injection is not recommended, as it can lead to rebound disease activity. If you and your healthcare provider decide to discontinue treatment, a proper plan and alternative therapy should be in place.

Q 5. Are there any specific dietary restrictions while on Tysabri 300mg injection?

There are no specific dietary restrictions associated with Tysabri 300mg injection. However, maintaining a balanced diet is essential for overall health.

Q 6. What should I do if I experience an infusion reaction during treatment?

If you experience an infusion reaction, alert the healthcare provider immediately. They will manage the symptoms and determine if further action is needed.


Fact Box of Tysabri 300mg Injection

Molecule name: Natalizumab

Therapeutic class: Immunomodulatory agent

Pharmacological class: Integrin Antagonist

Indications: 

1. Multiple Sclerosis (MS) 

2.Crohn's Disease 


References

  1. Biogen Netherlands BV, Electronic medicines compendium (emc), [Revised on 15th July 2022] [Accessed on 30th July 2023],https://www.medicines.org.uk/emc/product/222/smpc#gref 
  2. Elan Pharmaceuticals, Inc, US Food and Drug Administration, [Revised on  08/2017][ Accessed on 30th July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/1215104s959lbl.pdf 
  3. Rachel Branstadter, Ilana Katz Sand; The use of Tysabri 300mg injection for multiple sclerosis; Neuropsychiatrist Disease and Treatment; Published on June 2017; Accessed on 30th July 2023; http://www.ncbi.nlm.nih.gov/pmc/articles/pmc5499927/ 

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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