TYSABRI 300MG INJECTION

Introduction:

Tysabri 300mg Injection contains the active substance natalizumab. It is used to treat multiple sclerosis (MS) in adult patients. It decreases the number of MS attacks and slows the worsening of disability associated with this condition. This Injection is also used to reduce symptoms and signs of Crohn’s disease. It is not recommended for adolescents and children below the age of 18 years. 

MS is a chronic disorder that can affect the spinal cord, brain, and optic nerves in the eyes. Symptoms vary from person to person but typically include walking difficulties, feeling off-balance and visual difficulties (e.g., blurred or double vision). Crohn’s disease can cause inflammation in different areas of the digestive tract in different people and lead to abdominal pain, weight loss, tiredness, severe diarrhea, and malnutrition.

Before taking Tysabri 300mg Injection, let your physician know if you have immune system disorders, brain infection, cancer, or other diseases. This medication contains sodium. If you are on a salt-controlled diet, talk with the health care provider.

Uses of Tysabri 300mg Injection:

• Multiple sclerosis
• Crohn’s disease

How Tysabri 300mg Injection works:

Natalizumab works by stopping certain immune cells from getting into the brain, spinal cord, or digestive tract and prevents inflammation and nerve damage.

Interactions with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

More information:

• Keep Tysabri 300mg Injection out of sight and reach of children. 
• Store in a refrigerator. Do not freeze. 

References:

1. Biogen Netherlands BV, Electronic medicines compendium (emc), [Revised on July 2021] [ Accessed on 11th May 2022], https://www.medicines.org.uk/emc/files/pil.222.pdf
2. Elan Pharmaceuticals, Inc, US Food and Drug Administration, [Revised on Jan 2012] [ Accessed on 11th May 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/125104s0576lbl.pdf  
3. Rachel Branstadter, Ilana Katz Sand; The use of natalizumab for multiple sclerosis; Neuropsychiatrist Disease and Treatment; Published on June 2017; Accessed on 11/05/2022; http://www.ncbi.nlm.nih.gov/pmc/articles/pmc5499927/

How to use Tysabri 300mg Injection:

It will be given to you by your health care professional.

Safety advice:

Pregnancy:

Use of Tysabri 300mg Injection during pregnancy is not recommended. You need to tell your physician if you are pregnant before taking this medication.

Breastfeeding:

Use of Tysabri 300mg Injection during breastfeeding is not recommended. You need to tell your physician if you are breastfeeding before taking this medication. He/ she will help you decide whether to stop breastfeeding or stop receiving this drug. 

Driving: 

Tysabri 300mg Injection can cause dizziness. Avoid driving if you are unwell.

Others:

Talk to your physician if you:

• Cancer, brain infection, or immune system disorders.
• Are taking drugs that suppress the immune system.
• Are on a salt-controlled diet.
• Have allergic conditions or other disorders. 

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Common:

• Headache, dizziness
• Nausea, vomiting
• Runny or stuffed nose
• Joint pain
• Tiredness
• Urinary tract infection
• Sore throat
• Anemia
• Shivering
• Itchy rash
• Fever
• Reddening of face or body
• Difficulty breathing