UROMITEXAN 200MG INJECTION

Introduction:

Uromitexan 200mg Injection contains the active constituent mesna. It is used to reduce the risk of hemorrhagic cystitis (inflammation and bleeding of the bladder) and conditions in which blood is present in the urine (microhematuria & macrohematuria) in patients treated with Ifosfamide and cyclophosphamide. Ifosfamide and cyclophosphamide are medicines used in the treatment of cancer and may cause the above-said conditions as side effects. 

Before starting treatment with Uromitexan 200mg Injection, talk to the physician if you have any medical conditions, are pregnant or breastfeeding. You must drink an adequate quantity of liquids (one to two liters) each day during the treatment. Nausea, vomiting, low blood count, fever, tiredness, hair loss, and sleepiness are common side effects of Uromitexan 200mg Injection. 

Uses of Uromitexan 200mg Injection:

In patients receiving Ifosfamide and cyclophosphamide, Uromitexan 200mg Injection lowers the risk of: 

• Hemorrhagic cystitis (inflammation & bleeding of the bladder)
• Microhematuria and macrohematuria (conditions in which urine contains blood)

How Uromitexan 200mg Injection works:

Uromitexan 200mg Injection binds to the toxic metabolites of Ifosfamide and cyclophosphamide and makes them less harmful.

Interactions with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

More information:

• Keep Uromitexan 200mg Injection out of sight and reach of children. 
• Store below 25°C.

References:

1. Baxter Healthcare Corporation, US Food and Drug Administration, [Revised on March 2014] [ Accessed on 10th May 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/019884s013lbl.pdf
2. Baxter Healthcare Ltd, Electronic medicines compendium (emc), [Revised on Oct 2014] [ Accessed on 10th May 2022], https://www.medicines.org.uk/emc/product/1838
3. V Reddy, Winston NR; Mesna; NCBI Bookshelf; [Revised on Nov 2020] [Accessed on 10th May 2022], https://www.ncbi.nlm.nih.gov/books/NBK556021/

How to use Uromitexan 200mg Injection:

It will be given to you by your health care professional.

Safety advice:

Pregnancy:

You need to tell your physician if you are pregnant or planning to get pregnant before taking this medication. 

Breastfeeding:

You need to tell your physician if you are breastfeeding before taking this medicine. Your doctor will discuss with you and decide whether you will receive Uromitexan 200mg Injection or breastfeed as you must not do both. 

Liver:

You need to tell your physician if you have any liver disorders before taking Uromitexan 200mg Injection.

Kidney:

You need to let your health care provider know if you have any kidney disorders. 

Driving: 

Uromitexan 200mg Injection may cause sleepiness. Avoid driving if you are unwell.

Others:

• Talk to your physician if you have any diseases or allergic conditions before receiving Uromitexan 200mg Injection.

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Common:

• Nausea, vomiting
• Constipation
• Low blood cell count
• Tiredness
• Fever
• Diarrhea
• Stomach pain
• Hair loss
• Sleepiness
• Headache
• Weakness