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Zavicefta 2gm Injection
Prescription Required
Salt Composition : Ceftazidime,avibactam
Manufacturer : PFIZER LTD
Origin of Medicine : United States of America
1 Vial(s)
Introduction to Zavicefta 2gm Injection
Zavicefta 2gm injection contains two active ingredients in one injection. One of the active substances is Ceftazidime, which belongs to the group of medications called third-generation cephalosporin antibiotics. The other active substance is Avibactam belonging to the group of medications called beta-lactamase inhibitors. This combination is effective against a wide range of bacteria and is commonly used to treat serious infections such as pneumonia, urinary tract infections, and abdominal infections.
This drug is contraindicated in individuals with known hypersensitivity or allergy to it or its component. Report your physician if you are allergic to any antibiotic group. You may develop fits-like symptoms if you have administered too much of Zavicefta 2gm injection. Inform your doctor if you have a history of seizures or epilepsy. Use of this medication can lead to antibiotic-associated diarrhea, which ranges from mild to severe. If you experience severe diarrhea during or after treatment, inform your physician.
Zavicefta 2gm injection should be used cautiously in individuals with impaired kidney function. Your doctor may need to adjust the dosage based on your kidney function and closely monitor your kidney health during treatment. Notify your physician if you are pregnant or breastfeeding. It is necessary to consult this with your physician for more advice.
Uses of Zavicefta 2gm Injection
- Pneumonia
- Urinary tract infections
- Abdominal infections
Therapeutic Effects of Zavicefta 2gm Injection
Ceftazidime is a cephalosporin antibiotic that inhibits bacterial cell wall synthesis, while Avibactam is a beta-lactamase inhibitor. Avibactam helps protect Ceftazidime from being degraded by beta-lactamase enzymes, allowing the antibiotic to kill the bacteria effectively.
Interaction of Zavicefta 2gm Injection with other drugs
Notify your physician about all the medicines you take, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications interact with Zavicefta 2gm injection and reduce their effectiveness by causing undesirable side effects.
More Information about Zavicefta 2gm Injection
- Store the Zavicefta 2gm injection below 25°C
- Keep the medicine out of reach of children and pets.
How to consume Zavicefta 2gm Injection
Do not self-administer the Zavicefta 2gm injection. Your doctor will decide the duration and dose of your treatment based on the disease severity and other factors. It will be given as an intravenous infusion, and you will be monitored carefully for unwanted side effects.Â
Safety Advices for Zavicefta 2gm Injection
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Pregnancy
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If you are pregnant, suspecting, or planning for the pregnancy, report to your doctor before starting the treatment with Zavicefta 2gm injection.
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Breast Feeding
 ÂIf breastfeeding, consult your doctor before starting the treatment with Zavicefta 2gm injection.
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Lungs
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Zavicefta 2gm injection is safe to use and can be prescribed for patients with lung problems. Consult your physician if you have any lung diseases before starting the treatment.
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Liver
  Consult your physician for advice before starting the treatment with Zavicefta 2gm injection. If you have liver problems, ensure your physician monitors your liver functions regularly.
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Alcohol
 ÂIt is unknown whether consuming alcohol while taking Zavicefta 2gm injection is safe. Please speak with your physician.
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Driving
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It is unsafe to use Zavicefta 2gm injection because it alters your ability to drive and operate heavy machinery.
Side Effects of Zavicefta 2gm Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Severe allergic reactions (swelling of lips, face, or throat, rash, difficulty swallowing or breathing)
- Severe or bloody diarrhea
Common
- Fever
- Headache, dizziness
- Itching, redness, or swelling in the injection site
- Stomach pain
- Nausea, vomiting
- Change in the number of certain types of blood cells
- Fungal infections
Word of Advice
Finish the entire prescribed course of Zavicefta 2gm injection, even if you start feeling better before the completion. Stopping the medication suddenly can lead to incomplete treatment and the risk of recurrent or resistant infections. Notify your doctor if you have allergies to cephalosporin antibiotics, penicillins, or other medications. Also, report any adverse reactions or side effects you experience during treatment.
FAQs
Q 1. Is it necessary to follow a special diet while taking Zavicefta 2gm injection?
While taking Zavicefta 2gm injection, drinking adequate fluids, such as water, is generally recommended to support kidney function and prevent dehydration.
Q 2. Can Zavicefta 2gm injection cause allergic reactions?
Yes, like other antibiotics, Zavicefta 2gm injection can cause allergic reactions in some individuals. If you experience symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing, seek immediate medical attention.
Q 3. How is Zavicefta 2gm injection administered?
Zavicefta 2gm injection is usually administered through intravenous (IV) infusion. The duration and dosage of treatment are based on the type and severity of the infection and the patient's specific medical condition. The administration is done in a healthcare setting, such as a hospital.
Q 4. What types of infections are treated with Zavicefta 2gm injection?
Zavicefta 2gm injection is primarily used to treat complicated urinary tract infections (cUTIs), including pyelonephritis (kidney infection) and complicated intra-abdominal infections (cIAIs). It may also treat hospital-acquired pneumonia (HAP), including ventilator-associated pneumonia (VAP).
Q 5. How does Zavicefta 2gm injection work?
Ceftazidime is a cephalosporin antibiotic that inhibits bacterial cell wall synthesis, while Avibactam is a beta-lactamase inhibitor. Avibactam helps protect Ceftazidime from being degraded by beta-lactamase enzymes, allowing the antibiotic to kill the bacteria effectively.
Fact Box of Zavicefta 2gm Injection
Molecule name: Ceftazidime + Avibactam | Therapeutic class: Antibiotics |
Pharmacological class:Â 1. Ceftazidime- Third generation cephalosporins 2. Avibactam- Beta-lactamase inhibitor | Indications:Â 1. Pneumonia 2. Urinary tract infections 3. Abdominal infections |
References
- Pfizer Limited, Electronic medicines compendium (EMC), [Revised on June 2022] [ Accessed on 26th June 2023], https://www.medicines.org.uk/emc/files/pil.2465.pdf
- Zavicefta, Annex I summary of Product Characteristics - European Medicines Agency.[ Accessed on 26th June 2023],https://www.ema.europa.eu/en/documents/product-information/zavicefta-epar-product-information_en.pdf
- Allergan USA, Inc, US Food and Drug Administration, [Revised on March 2019] [ Accessed on 14th March 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/206494s005,s006lbl.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Antimicrobial drugs, 7th edition, 2013,728.
- Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Penicillins, Cephalosporins and other Beta-Lactam Antibiotics, 12th edition, 2011, 1498.
Disclaimer
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