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Zyramod 25mg Tablet

Prescription Required

Salt Composition : Iguratimod

Manufacturer : ZYDUS CADILA

Origin of Medicine : India

MRP: 272.25
Price :244
You Save :28 (10%)

10 Tablet(s) In A Strip

Introduction to Zyramod 25mg Tablet

Zyramod 25mg tablet contains an active component of Iguratimod. It is a medication used for the treatment of rheumatoid arthritis and other autoimmune diseases like ankylosing spondylitis, psoriatic arthritis, systemic lupus erythematosus (SLE), juvenile idiopathic arthritis (JIA) and behçet's disease. It is an oral disease-modifying antirheumatic drug (DMARD) that helps to reduce inflammation and manage symptoms associated with these conditions. Ankylosing spondylitis is a chronic inflammatory arthritis primarily affecting the spine and pelvis. Psoriatic arthritis is an inflammatory arthritis that can affect joints, skin, and nails, often occurring in individuals with psoriasis. Systemic Lupus Erythematosus (SLE) is an autoimmune disease that can affect various body parts, leading to inflammation, pain, and damage to organs and tissues. Juvenile Idiopathic Arthritis (JIA) is a type of arthritis that begins in childhood, causing joint inflammation and potentially affecting a child's overall health and growth. Behçet's Disease is a rare autoimmune disorder characterized by inflammation that can affect various body parts, leading to symptoms such as mouth and genital ulcers, skin lesions, and eye inflammation.

Be familiar with the signs and symptoms of hypersensitivity reactions, including skin rash, hives, itching, swelling (especially of the face, lips, or throat), difficulty breathing, and chest tightness. If you experience any of these symptoms, seek medical attention immediately. Inform your healthcare provider about known allergies, especially if you have had previous hypersensitivity reactions to medications. Zyramod 25mg tablet is contraindicated in individuals with severe hepatic, renal, or significant hematological abnormalities. Avoiding Zyramod 25mg tablet in these cases is important to prevent potential adverse reactions or complications. For children, this medication should be used under the guidance of a pediatric rheumatologist, with careful consideration of dosage, growth monitoring, and open communication with caregivers. Consulting a geriatric specialist is crucial for older adults to assess potential interactions, adjust dosages, and ensure regular follow-up while emphasizing fall prevention, hydration, and nutrition to support safe and effective treatment.

Uses of Zyramod 25mg Tablet

Zyramod 25mg tablet is used in the following:

  • Rheumatoid arthritis
  • Ankylosing spondylitis
  • Psoriatic arthritis
  • Systemic lupus erythematosus
  • Juvenile idiopathic arthritis
  • Behçet's disease

Therapeutic Effects of Zyramod 25mg Tablet

Zyramod 25mg tablet's mechanism of action involves suppressing the production of pro-inflammatory cytokines, such as IL-1, IL-6, and TNF-α, which contribute to autoimmune responses and inflammation. It may also modulate T cell activity, downregulate inflammatory mediators like COX-2 and MMPs, and influence immune cell activation, collectively reducing inflammation and mitigating damage caused by autoimmune diseases. Additionally, It's potential antioxidant properties could further contribute to its anti-inflammatory effects.

Interaction of Zyramod 25mg Tablet with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Zyramod 25mg tablet, reducing effectiveness by causing undesirable side effects. 

More Information about Zyramod 25mg Tablet

  • Store at room temperature, between up to 20°C to 25°C (68°F to 77°F)
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Zyramod 25mg Tablet

Zyramod 25mg tablet is typically administered orally, which means it is taken by mouth. It is available in the form of tablets or capsules that are ingested with water. Always follow your healthcare provider's instructions regarding the correct dosage, timing, and frequency of administration for this medication. 

Safety Advices for Zyramod 25mg Tablet

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Zyramod 25mg tablet is not recommended during pregnancy. It is advised to avoid this medication. If you are pregnant or planning to become pregnant, as the safety of the developing fetus has not been established.

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Breast Feeding


Zyramod 25mg tablet is not recommended while breastfeeding, as it is unknown if the drug passes into breast milk.

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If you have lung conditions such as chronic obstructive pulmonary disease (COPD) or interstitial lung disease, consult your healthcare provider before starting Zyramod 25mg tablet.

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If you have liver conditions, including hepatitis or cirrhosis, you should consult a healthcare provider before starting this medication.

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It is advisable to avoid or limit alcohol consumption while taking Zyramod 25mg tablet, as alcohol can interact with medications and potentially increase the risk of side effects or complications.

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Zyramod 25mg tablet is not known to impact driving or operating machinery significantly. However, always consult your healthcare provider if you experience dizziness, drowsiness, or any other side effects.

Side Effects of Zyramod 25mg Tablet

Zyramod 25mg tablet causes some side effects like all medications, although not everyone will experience them. 


  • Liver Effects
  • Hematologic Effects
  • Allergic Reactions
  • Gastrointestinal Issues


  • Gastrointestinal upset
  • Rash and skin reactions
  • Elevated liver enzymes
  • Upper respiratory tract infections
  • Headache
  • Fatigue

Word of Advice

Be careful for serious allergic reactions, particularly if rash, swelling, or breathing difficulties occur. Pregnant and breastfeeding individuals should avoid Zyramod 25mg tablet. Use caution if you have lung, liver, cardiovascular, or eye conditions, and discuss bone health, immunizations, and mental health with your healthcare provider. Limit alcohol consumption, be cautious with driving and machinery if drowsiness occurs, and protect your skin from sunlight. Communicate pre-existing medical conditions, infections, or surgery plans with your doctor. If you experience unusual symptoms, such as respiratory issues or mood changes, seek prompt medical attention. Follow dosing instructions consistently, attend follow-up appointments, and consult your doctor for personalized guidance based on your health profile.


Q 1. Can Zyramod 25mg tablet be used long-term?

Long-term use of Zyramod 25mg tablet may be necessary to manage chronic autoimmune conditions. Your healthcare provider will determine the appropriate duration of treatment based on your individual needs and response.

Q 2. What should I do if I miss a dose of Zyramod 25mg tablet?

If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Q 3. Can I stop taking Zyramod 25mg tablet if my symptoms improve?

No, following your doctor's instructions regarding medication use is important. Stopping Zyramod 25mg tablet abruptly could lead to a flare-up of symptoms. Always consult your healthcare provider before making any changes to your treatment plan.

Q 4. Can I continue my regular physical activities and exercise routine while on Zyramod 25mg tablet?

In general, you can continue your physical activities while taking Zyramod 25mg tablet. However, if you experience joint pain or other symptoms, consult your doctor for guidance on adjusting your exercise routine.

Q 5. Is it safe to receive vaccinations while on Zyramod 25mg tablet?

Consult your healthcare provider before receiving any vaccines while on Zyramod 25mg tablet, as the medication may affect your immune response to vaccinations.

Q 6. Can Zyramod 25mg tablet affect my vision?

While vision changes are not a common side effect, inform your healthcare provider if you experience any visual disturbances or eye discomfort.

Fact Box of Zyramod 25mg Tablet

Molecule name: Iguratimod

Therapeutic class: Antirheumatic Agents

Pharmacological class: Disease-Modifying Antirheumatic Drugs (DMARDs)


1. Rheumatoid arthritis

2. Ankylosing spondylitis 

3. Psoriatic arthritis

4. Systemic lupus erythematosus

5. Juvenile idiopathic arthritis

6. Behçet's disease


  1. Huihui Jiang et al; Molecular mechanisms and clinical application of Zyramod 25mg tablet: A review; Biomedicine & Pharmacotherapy; Published on Feb 2020; Accessed on 09/08/2023;
  2. Novartis Pharmaceuticals UK Ltd, Electronic medicines compendium (emc), [Revised on 25th Jul 2022] [Accessed on 9th August 2023],
  3. Sisi Xie et al; Zyramod 25mg tablet as a New Drug for Rheumatoid Arthritis: Current Landscape; Frontiers in Pharmacology; Published on 26/02/2020; Accessed on;  09/08/2023
  4. Jie Li et al; Zyramod 25mg tablet: a valuable remedy from the Asia Pacific region for ameliorating autoimmune diseases and protecting bone physiology; Bone Research; Published on Sept 2019; Accessed on 09/08/2023;


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