This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
2-Deoxy-D-Glucose is an antiviral drug used to treat moderate to severe COVID-19. FDA approved it initially on May 8, 2021.
Mechanism of Action of undefined
2-Deoxy-D-Glucose is a medicine that resembles glucose structurally and is used to kill the virus causing Covid-19. The virus utilizes glucose to produce energy, which it uses to make copies of itself. Once given, the medicine is readily absorbed by the ‘virus-infected cells’ as the virus takes it up just like glucose. On reaching the infected cells, the medicine stops energy production, inhibits further virus multiplication, and kills it. This helps in clearing the infection, even if it has spread to the lungs, and reduces the requirement for supplemental oxygen in moderate to severely infected Covid-19 patients.
Uses of undefined
It is a glucose molecule in which the 2-hydroxyl group gets replaced by hydrogen. It is used to moderate to severe COVID-19. The drug is used as an adjunct therapy.
undefined Drug administaration and Dosage available
Oral Powder is recommended for use in hospital or institutional setup only. Your doctor will decide the dose and duration of the treatment. You will be monitored by your healthcare provider while giving this medicine. It is important to keep in mind that this medicine is to be given only in emergency cases. You should not take this medicine without the prescription of the doctor. Check the label for directions before use. The sachet may be taken with or without food, but it is better to take it at a fixed time.
Warnings, Precautions and Side Effects of undefined
The warnings of this medicine are still being investigated and studied. This medicine is intended to increase the blood sugar levels. Inform your physician if you are a diabetic patient. Increased risk of GI bleeding and QTc prolongation has been reported in patients using this medicine in long-term.
Do not take 2-Deoxy-D-Glucose if you are allergic to 2-Deoxy-D-Glucose or any of the other ingredients. Inform your physician if you have liver problems or kidney diseases before initiating the treatment. Notify your doctor if you have been treated with any other drugs for COVID-19. This medicine is intended only for individuals aged 18 years and above. Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with 2-Deoxy-D-Glucose and reduce its effectiveness by causing undesirable side effects.
The Potential side effects of this medicine include increased blood sugar levels, increased risk of GI bleeding, and QTc prolongation. The frequent side effects are not well established.
Word Of Advice
Store below 2-Deoxy-D-Glucose 30°C. Protect the medicine from light and excessive moisture. Keep the medicine out of reach of children and pets. If you forgot to take the tablet, take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose. Limited information is available on the use of 2-Deoxy-D-Glucose in patients with kidney disease. Please consult your doctor. It helps the faster recovery of hospitalized COVID-19 patients and reduces supplemental oxygen dependence. The medicine comes in powder form in a sachet, which is taken orally by dissolving it in water twice daily. However, it should be consumed only on the advice of a doctor. Follow your doctor's instructions carefully, and let your doctor know if you have any other concerns.
Frequently Asked Question
- Calcium, Global. “2 Deoxy D Glucose Manufacturer in India | CAS 154-17-6 | Global Calcium.” Www.globalcalcium.com, www.globalcalcium.com/products/2-deoxy-d-glucose. Accessed 22 May 2023.https://www.globalcalcium.com/products/2-deoxy-d-glucose
- Sahu, KamalK, and Raman Kumar. “Role of 2-Deoxy-D-Glucose (2-DG) in COVID-19 Disease: A Potential Game-Changer.” Journal of Family Medicine and Primary Care, vol. 10, no. 10, 2021, p. 3548, https://doi.org/10.4103/jfmpc.jfmpc_1338_21. Accessed 13 Feb. 2022.https://journals.lww.com/jfmpc/Fulltext/2021/10100/Role_of_2_Deoxy_D_Glucose__2_DG__in_COVID_19.5.aspx
The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.