This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

On April 28, 2011, the U.S. FDA approved Abiraterone acetate to be used in Combination with prednisone for the treatment of patients with metastatic castration-resistant prostate cancer who have received prior chemotherapy containing docetaxel.

Mechanism of Action of undefined

Prostate cancer occurs due to excessive production of male hormones (androgens/ testosterone). Androgens are produced by the testicles, adrenal glands and metastatic tumor. Abiraterone acetate works by interfering and inhibiting the enzyme CYP17A1 that acts as a catalyst in the production of the androgens. Inhibition of this enzyme, reduces the amount of androgens produced in the body.

Uses of undefined

Abiraterone acetate is used in treatment of prostate cancer.

undefined Drug administaration and Dosage available

This medication is to be taken as prescribed by your doctor. Abiraterone acetate is administered orally (by mouth) and the recommended dose is 1000mg (two tablets) once a day. This medication is not to be taken with food and must be consumed whole without breaking it.

Warnings, Precautions and Side Effects of undefined


Abiraterone acetate is unsafe during pregnancy as it may cause harm to the unborn baby. This medication must not be taken with food. If you are lactose intolerant inform your doctor before starting treatment with this medication as it contains lactose. Inform your doctor if you are on a salt control diet as it contains sodium.


Inform your doctor if you have liver disease, high blood pressure, heart failure or low blood potassium levels, and high sugar levels. Effective contraception is to be followed while being treated with Abiraterone acetate. Inform your doctor about any medications you are taking before starting treatment with this medication.

Side Effects

The common side effects of Abiraterone acetate are bone fracture, indigestion, blood in urine, rash, diarrhea, high fat levels in the blood, chest pain, irregular heartbeat, rapid heart rate, urinary tract infection, fluid in the legs or feet, high BP, and low blood potassium levels in the body (serious).

Word Of Advice

Abiraterone acetate is to be taken once daily without food. This medication must be taken after two hours of taking food. Once the medication is taken, food must be eaten only after at least one hour.

Frequently Asked Question


1. Centocor Ortho Biotech Inc, US Food and drug administration, [ Revised date: APR 2011] [ Accessed date: 26 MAY 2022], 
2. Janssen- Cilag International NV, Electronics Medicine Compendium (emc), [Revised date: SEP 2021] [ Accessed date: 26 MAY 2022] 
3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Natural products in cancer chemotherapy: hormones and related agents, 12th edition, 2011, 1707 - 1709. 


The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.