This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

The FDA approved Adrenaline bitartrate for medical use on 12/07/2012 for emergency treatment of allergic reactions (anaphylaxis).

Mechanism of Action of undefined

Adrenaline bitartrate works on two types of receptors in your body, called alpha (α) and beta (β) receptors, in various organs:

  • Heart: It makes your heart pump stronger and faster, which can be helpful during a heart emergency like cardiac arrest.
  • Blood vessels: It tightens your blood vessels, which can be used when treating low blood pressure in cases like septic shock.
  • Lungs: It relaxes the muscles in your lungs, making breathing easier if you have a severe allergic reaction (anaphylaxis).
  • Eyes: It makes your pupil (the black part in your eye) get bigger, which helps doctors during eye surgery to operate better.

Uses of undefined

Adrenaline bitartrate is used to rapidly relieve severe allergic reactions to drugs or other substances causing allergies. It is a primary drug administered during cardiopulmonary resuscitation (CPR) to reverse cardiac arrest. Additionally, it is employed in emergency shock treatment resulting from a severe allergic reaction. Furthermore, it plays a crucial role in assisting surgeons by inducing and maintaining mydriasis (enlarging the pupil) during eye surgery.

undefined Drug administaration and Dosage available

Adrenaline bitartrate is available as a 1mg injection for intravenous, intramuscular, and subcutaneous use to be administered by your healthcare provider. Your doctor will decide the most suitable dosage for your case according to your age and physical circumstances.

Warnings, Precautions and Side Effects of undefined

Warnings

Adrenaline bitartrate should be avoided under certain circumstances and in specific medical conditions. Inform your healthcare provider if you have a known allergy to adrenaline or its components in the injection. Additionally, it is not recommended during pregnancy, in cases of severe heart disease, and when suffering from brain infections, diseases, or tumors. Tell your doctor if you have atherosclerosis, a condition characterized by the narrowing and hardening of blood vessels. Engaging in transparent communication with your doctor regarding your medical history and medications is crucial to ensure the safe and proper use of adrenaline injections.

Precautions

Before the treatment with adrenaline bitartrate, consult your doctor if you are pregnant, planning to conceive, or breastfeeding. Additionally, inform your doctor about any existing lung or liver conditions. It is unknown whether alcohol is safe with this injection, so consult your doctor for advice. If you experience dizziness, refrain from driving or operating machinery, and consult your doctor for guidance. These precautions emphasize the need for personalized medical advice when using adrenaline bitartrate.

Side Effects

drenaline can cause some side effects like any other drug. Common side effects include anxiety, tremors, weakness, sweating, nausea, and respiratory difficulties. Stress cardiomyopathy may lead to chest pain, shortness of breath, and irregular heartbeat. Patients should be vigilant and promptly report any severe reactions to healthcare providers.

Word Of Advice

Since adrenaline bitartrate is an emergency drug, you will be under medical supervision during and, if necessary, after the treatment. If you experience any side effects during or after treatment, inform your healthcare provider promptly. Avoid spicy and fatty foods. Take plant-based diets. Avoid alcohol and quit smoking to resume a healthy lifestyle.

Frequently Asked Question

References

  1. Mercury Pharmaceuticals Ltd, Electronic medicines compendium (EMC), [Revised on Nov 2018], [Accessed on 26th Sept 2023], https://www.medicines.org.uk/emc/product/6595/pil
  2. Belcher Pharmaceuticals, US Food and Drug Administration (FDA), [Revised on Jul 2021], [Accessed on 26th Sep 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/205029s006lbl.pdf
  3. KD Tripathi, Essentials of Medical Pharmacology, Adrenergic Transmission and Adrenergic Drugs, 8th edition, 2019, 145-152
  4. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Adrenergic agonists and Antagonists,13th edition, 2018, 194-196

Disclaimer

The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.