Uses of undefined

Afatinib dimaleate is used to treat certain types of cancer, including non-small cell lung cancer with specific EGFR mutations.

undefined Drug administaration and Dosage available

Afatinib dimaleate is an oral medication that is usually taken once a day, at approximately the same time each day, before food. If you have already eaten, wait at least 3 hours before taking this medicine.

It should be taken as prescribed by a doctor. These tablets should be swallowed whole with a glass of water. They should not be crushed, chewed, or opened, as this can affect how the medication is absorbed and decrease its effectiveness. Take the missed dose as soon as you recall if your next planned dose is more than eight hours away. You should not take a double dose to make up for the second dose.

Warnings, Precautions and Side Effects of undefined

Warnings

It is not recommended to use this medication if you are allergic to the active compound afatinib dimaleate or its components. It is not recommended for female patients weighing below 50 kilograms.  Afatinib dimaleate can cause interstitial lung disease (ILD), a serious and potentially life-threatening condition that can cause inflammation and scarring of the lungs. This medication can cause severe diarrhea and dehydration, which can be life-threatening in some cases. Sometimes this medication results in eye problems, such as corneal erosion or ulceration, which can lead to vision loss or blindness. It is not recommended for children and adolescents under the age of 18. 

Precautions

 It is not recommended to use during pregnancy and breastfeeding, it is advised to consult your physician regarding further queries.  Tell your doctor if you have a history of eye problems or wearing contact lenses. Limit your time in the sun as this medicine may make your skin sensitive to the sun. Patients with pre-existing cardiac conditions and renal problems should monitor kidney and heart function regularly before and while taking afatinib dimaleate. Any signs or symptoms of dehydration, such as dry mouth or decreased urination, should report to a healthcare provider immediately. You should avoid any traumatic or penetrative procedure in the body, like tooth extraction or surgery while taking this medication because it can result in excessive bleeding.

Side Effects

Afatinib dimaleate can cause various side effects, ranging from mild to severe. Some common side effects include diarrhea, skin rash, nail changes, mouth sores, and fatigue. These side effects can often be managed with medication or other treatments. However, it can also cause more serious side effects, such as severe diarrhea, dehydration, and kidney problems, interstitial lung disease and Hemorrhage or bleeding problems.

Word Of Advice

Follow all instructions and dosing recommendations provided by your healthcare provider. Do not take more or less of the medication than prescribed. Report any new or worsening symptoms to your healthcare provider immediately, especially if they relate to your lungs, eyes, skin, liver, kidneys, heart, or bleeding. Women should avoid pregnancy or breastfeeding. Men and women of reproductive-age should use effective birth control during the treatment and for at least two weeks after your last dose. Patients should report any signs or symptoms of dehydration, such as dry mouth or decreased urination, to a healthcare provider immediately. It is advised to drink plenty of fluids while taking afatinib dimaleate to stay hydrated, especially if you experience diarrhea as a side effect. When taking afatinib dimaleate, stay away from grapefruit and grapefruit juice as they may interact with the medication and raise the risk of side effects.

Frequently Asked Question

• Can I donate blood while taking afatinib dimaleate?
• Patients should not donate blood while taking afatinib dimaleate, as the medication can harm the recipient. It is important to inform your healthcare provider if you plan to donate blood, as they may advise you to wait until after you have finished treatment.

• Can I continue to work or go to school while taking Afatinib dimaleate?
• The ability to work or go to school while taking afatinib dimaleate will depend on your condition and response to treatment. Some patients may experience fatigue or other side effects that can impact their ability to perform daily activities.

• Does afatinib dimaleate have any effect on fertility?
• There is limited information on the effects of afatinib dimaleate on fertility. However, it is important to inform your healthcare provider if you are trying to conceive, as some cancer treatments can affect fertility.

• Can I take afatinib dimaleate if I have a history of heart problems?
• If you have a history of heart problems, discussing the potential risks and benefits of using afatinib dimaleate with your healthcare provider before starting treatment is important. This medication can cause cardiac problems, and your healthcare provider may need to monitor you closely during treatment.

• Can afatinib dimaleate be used in combination with other cancer treatments?
• Afatinib dimaleate is sometimes used in combination with other cancer treatments, such as chemotherapy or immunotherapy. However, the safety and effectiveness of these combinations will depend on your individual condition and treatment plan.