This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Alfuzosin HCL + tadalafil was approved for medical use to manage benign prostatic hyperplasia and treat erectile dysfunction.
Mechanism of Action of undefined
The combination medication alfuzosin HCL + tadalafil works by relaxing muscles in the prostate and bladder, making it easier to urinate for men with an enlarged prostate (BPH). Additionally, tadalafil enhances blood flow to the penis, helping men achieve and maintain erections dysfunction (ED) during sexual stimulation.
Uses of undefined
Alfuzosin HCL + tadalafil is used to treat lower urinary tract symptoms associated with benign prostatic hyperplasia and treat erectile dysfunction during sexual stimulation. Erectile dysfunction (ED) arises from insufficient blood flow, leading to the inability to sustain an erection during sexual stimulation. Benign prostatic hyperplasia (BPH) occurs when the prostate glands enlarge, causing lower urinary tract symptoms (LUTS) such as urinary obstruction, poor urination, and bladder pain. BPH also increases the risk of urinary retention.
undefined Drug administaration and Dosage available
Alfuzosin HCL + tadalafil is available in tablet form in two different strengths: 2.5mg and 5mg. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.
Warnings, Precautions and Side Effects of undefined
Warnings
Alfuzosin + tadalafil is not meant for use in women. Avoid taking alfuzosin + tadalafil if you are allergic to alfuzosin hydrochloride, tadalafil, or any of its components. It is also not advisable if you have recently taken nitrates (medicines used for angina or chest pain), experienced a heart attack in the past three months, had a stroke or heart failure in the past six months, or have severe liver or kidney impairment. It's crucial to inform your doctor about these conditions and provide a comprehensive overview of your medical history and all medications before starting this treatment.
Precautions
Inform your healthcare provider about any pre-existing lung diseases and severe liver conditions before starting the medication. Alcohol consumption is discouraged due to its impact on erection and dizziness. Additionally, avoid driving or operating heavy machinery due to potential dizziness and sleepiness. Always consult your doctor for personalized advice and guidance.
Side Effects
Alfuzosin + tadalafil can cause some side effects like any other drug. Some of the serious side effects include skin reactions, palpitations (increased heartbeats), and priapism (prolonged erection). Common side effects include dizziness, low blood pressure, headache, constipation, diarrhea, nausea, vomiting, and dry mouth. It's important to be aware of these potential reactions and consult a healthcare professional if you experience any of these symptoms while taking this medication.
Word Of Advice
It is important to be mindful of potential side effects while using alfuzosin and tadalafil. If you experience dizziness after taking the medication, it is advisable to sit or lie down to prevent falls due to low blood pressure. Priapism, a rare but serious side effect of this medication where an erection lasts for more than 4 hours after sexual intercourse, can occur. If you experience prolonged and painful erections, immediate medical attention is necessary to prevent permanent erectile dysfunction.
Regular screenings for prostate cancer are crucial, especially since it often coexists with benign prostatic hyperplasia (BPH). If you're considering cataract surgery, inform your eye specialist about your medication. Exercise caution with grapefruit juice consumption, as it may affect the medication's effectiveness. If you have sugar intolerance, consult your doctor before taking this medication to ensure it is safe for you. Embracing a nutritious diet and incorporating regular physical activity not only boosts general well-being but can also lower the risk of erectile dysfunction and improve sexual performance.
Frequently Asked Question
References
- Cipla, Electronic medicines compendium (EMC), [Revised on Oct 2017] [Accessed on Nov 2023] https://www.medicines.org.uk/emc/product/10231/pil
- Zentiva Pharma UK Limited, Electronic medicines compendium (EMC), [Revised on Mar 2021] [Accessed on Nov 2023] https://www.medicines.org.uk/emc/product/3960/pil
- Oger S, et al., Combination of alfuzosin and tadalafil exerts an additive relaxant effect on human detrusor and prostatic tissues in vitro; Eur Urol; Published on Apr 2010; Accessed on 1/11/2023 https://pubmed.ncbi.nlm.nih.gov/19428174/
- KD Tripathi, Essentials of Medical Pharmacology, Androgens And Related Drugs, Drugs For Erectile Dysfunction, 8th edition, 2019, 328.
- Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Androgens and The Male Reproductive Tract, 2018, 840- 841
Disclaimer
The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.