This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Alpha Ketoanalogue is a nutritional supplement indicated to improve the nutritional status of patients with chronic kidney disease.
Mechanism of Action of undefined
Alpha Ketoanalogue is a biological agent that belongs to the class of nutritional supplements. After administration, the ketoanalogues undergo a process called transamination by taking nitrogen some non-essential amino acids. This process decreases the formation of urea and prevents accumulation of uremic toxins, thus improving kidney health.
Uses of undefined
Alpha Ketoanalogue has been developed to prevent and treat kidney damage in patients with chronic kidney disease with glomerular filtration rate less than 25 ml per minute. It corrects faulty protein metabolism due to low protein intake (less than 40g/day). It delays the disease progression and the onset of dialysis treatment by preserving the nutritional status.
undefined Drug administaration and Dosage available
Alpha ketoanalogue is available in the form of powder, granules and tablets. The dose and frequency vary according to body weight and glomerular filtration rate.
Warnings, Precautions and Side Effects of undefined
During the Alpha Ketoanalogue treatment, your doctor may periodically monitor your serum calcium, serum phosphate and other kidney parameters to prevent serious complications. Report to your doctor if you have been diagnosed with hereditary phenylketonuria.
There is no sufficient information about the impact of Alpha ketoanalogue in pregnant and breastfeeding women. Exercise caution before using Alpha ketoanalogue during pregnancy and breastfeeding.
Alpha Ketoanalogue is not associated with any serious side effects, however, hypercalcemia is the most common side effect. Your healthcare provider will regularly monitor your serum calcium levels to check for hypercalcemia and would suggest reducing the intake of calcium and vitamin D sources.
Word Of Advice
Eat a calorie-rich diet. Take Alpha Ketoanalogue only on your healthcare provider’s recommendation.
Frequently Asked Question
- Centor Pharma, [Revised on Jan 2021] [Accessed on 0th Aug 2022], https://www.centorpharma.com/downloads/2021/nephrology/NEFROGARD.pdf
- Wu C-H, Yang Y-W, Hung S-C, Kuo K-L, Wu K-D, Wu V-C, et al., (2017) Ketoanalogues supplementation decreases dialysis and mortality risk in patients with anemic advanced chronic kidney disease, PLoS ONE, 12(5): e0176847, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419544/pdf/pone.0176847.pdf
- Hospimax, [Accessed on 30th Aug 2022], http://www.hospimax.com/formulation/Pospondyl%20website%20data.pdf
- La Renon Healthcare Pvt Ltd., [Revised on 2019] [Accessed on 30th Aug 2022], https://www.larenon.com/wp-content/uploads/2019/03/IMPULOG.pdf
The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.