This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

The FDA approved amantadine hydrochloride for medical use on 24/08/2017 to treat uncontrolled, involuntary muscle movements in Parkinson's patients.

Mechanism of Action of undefined

Amantadine increases dopamine levels in the brain, alleviating Parkinson's disease symptoms. As an antiviral agent, it interferes with flu viruses, blocking cell entry and cell replication.

Uses of undefined

It is primarily used for Parkinson's disease (a brain disorder affecting movements) due to its beneficial effects on Parkinsonism. Originally developed as an antiviral for influenza A prevention, it is rarely used due to high resistance levels.

undefined Drug administaration and Dosage available

Adrenaline bitartrate injection is available as 100mg tablets for oral use. Swallow the tablets whole with water; do not crush them. Your physician will tell you the correct dose and frequency based on your disease severity, body weight, and other factors.

Warnings, Precautions and Side Effects of undefined


Before taking amantadine, consider certain conditions. It is not recommended to take this tablet if you're allergic to amantadine hydrochloride or its components, have lactose intolerance, epilepsy(seizures), ulcers, severe kidney disease, or are pregnant, planning pregnancy, or breastfeeding. Consult your doctor if uncertain. Additionally, consult your doctor before using amantadine if you have liver or kidney issues, heart problems, mental illnesses like schizophrenia(inability to think, feel, or behave), or glaucoma(increased pressure in the eyes). Communication about your medical history and medications is crucial before starting the treatment.


Before taking amantadine, inform your doctor if you are pregnant or planning to conceive. Taking amantadine is not advisable during pregnancy since it can cause potential harm to your baby. The same goes for breastfeeding, as the medication can pass into breast milk. If you have lung or liver diseases, consult your doctor before taking amantadine. Additionally, avoid alcohol while on this medication, and be cautious when driving or operating machinery, as it may cause dizziness and blurred vision. Stay safe, inform your doctor, and follow these guidelines closely.

Side Effects

Some side effects of amantadine hydrochloride can be serious, including convulsions (fits) and fainting. More common side effects may include swollen ankles, red blotchy spots on the skin, depression, confusion, difficulty sleeping, nightmares, nervousness, headaches, dizziness, trouble controlling movements, slurred speech, fast or irregular heartbeat, and low blood pressure when standing up. Constipation, sweating, and dry mouth are also reported side effects. It is important to be aware of these potential reactions and consult a healthcare professional if these symptoms occur while taking the medication.

Word Of Advice

During the treatment with amantadine, if you, your family, or your caregiver notice any unusual urges or cravings that you find difficult to resist, inform your doctor immediately. These impulses might lead you to engage in activities harmful to yourself or others, such as excessive gambling, eating, spending, or increased sexual thoughts or behaviors. These are known as impulse control disorders. Inform your doctor if you experience these symptoms since your doctor might need to modify or discontinue your amantadine hydrochloride dosage.

Additionally, if you encounter blurred vision or other visual issues, it is important to seek immediate attention from an eye doctor. Some patients may notice this medicine losing its effect after taking it regularly for a few months. Tell your doctor if you notice this.

Frequently Asked Question


  1. Alliance Pharmaceuticals, Electronic medicines compendium (EMC), [Revised on Jan 2023] [Accessed on 3rd Oct 2023]
  2. Vertical Pharmaceuticals, US Food and Drug Administration (FDA), [Revised on Feb 2018] [Accessed on 3rd Oct 2023]
  3. Carol Chang et al; Amantadine; National Library of Medicine; Published on April 2023; Accessed on 03/10/2022;
  4. Kd Tripathi, Essentials Of Medical Pharmacology, Drugs Acting On Central Nervous System, 8th Edition, 2019, 459-460
  5. Goodman & Gilman's, The Pharmacological Basis Of Therapeutics, Chemotherapy Of Infectious Diseases, 13th Edition, 2018, 1112-1114


The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.