This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Amlodipine, Atenolol tablets are antihypertensive medications belonging to the calcium channel blockers and cardioselective beta-blockers category. It was approved by the U.S. Food And Drug Administration to treat hypertension.
Mechanism of Action of undefined
Amlodipine blocks calcium entry into the smooth muscle cells of blood vessels and the heart. This action leads to the relaxation and widening of blood vessels, reducing peripheral resistance and improving blood flow. Atenolol is a beta blocker that primarily acts on the heart by blocking the effects of adrenaline and noradrenaline. Doing so reduces the heart rate, decreases the force of contraction of the heart muscles, and lowers blood pressure.
Uses of undefined
Amlodipine, Atenolol has been developed to treat hypertension. It is a chronic condition characterized by persistently high blood pressure levels. If the condition is left untreated or uncontrolled, it can increase the chance of cardiovascular problems, including heart attacks and strokes. This tablet is often prescribed when a single medication alone is ineffective in controlling blood pressure.
undefined Drug administaration and Dosage available
It is an orally available prescription drug. Your doctor will decide the duration and dose of the drug based on the disease condition and other factors. Always take an Amlodipine, Atenolol tablet as prescribed by your doctor. Take the tablet with or without food. Do not open, break, chew, or crush the tablet. Swallow the whole tablet with water.
Warnings, Precautions and Side Effects of undefined
Amlodipine, Atenolol should not be used in individuals with known hypersensitivity or allergic reactions to this drug or its components. This tablet is contraindicated in patients with aortic stenosis, which is the narrowing of the aortic valve in the heart. The medication can affect the normal functioning of the heart in this condition, and it should be avoided. If you have experienced heart failure following a heart attack, this drug should not be taken, and it is not suitable in such cases.
You must inform your physician about any liver or kidney problems you have. Individuals with impaired liver or kidney function may require dose adjustments or alternative medications. Notify your physician if you are pregnant, breastfeeding, or planning to have a baby. Grapefruit juice and grapefruit should be avoided by individuals taking Amlodipine, Atenolol. Grapefruit and its juice contain compounds that can inhibit the action of the enzyme called CYP3A4, leading to raised levels of the medication in the bloodstream.
The common side effects that are likely to occur while you are on the treatment with Amlodipine, Atenolol are ankle swelling, slow heart rate, palpitations, nausea, edema (swelling), muscle cramps, constipation, tiredness, cold extremities, sleepiness and headache.
Word Of Advice
Before starting Amlodipine, Atenolol tablet, or any medication, inform your healthcare professional about any existing medical conditions, allergies, or medications you take for other issues. This detail will help them to decide if this tablet suits them and if any precautions or adjustments are necessary. Avoid exceeding the recommended dose or frequency of use unless your doctor advises. This tablet should be stored in a safe place, out of the reach of children. Accidental ingestion of this drug by children can be harmful.
Frequently Asked Question
- Ipca Laboratories UK Ltd, Patient information leaflet, Atenolol Film-coated Tablets - medicines (EMC). [Revised on March 2022], Available at: https://www.medicines.org.uk/emc/files/pil.14693.pdf (Accessed 07 June 2023).
- Dr. Reddy's Laboratories (UK) Ltd, Patient information leaflet, Amlodipine- medicines (EMC). [Revised on July 2022], Available at: https://www.medicines.org.uk/emc/files/pil.3473.pdf (Accessed 07 June 2023).
- Amlodipine- food and drug administration (FDA). [Revised on May 2011], Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019787s047lbl.pdf#:~:text=Adult%20recommended%20starting%20dose%3A%205%20mg%20once%20daily,2.5%20mg%20to%205%20mg%20once%20daily.%20%282.2%29 (Accessed 07 June 2023).
- Package leaflet: Information for the user - Amlodipine. www.hpra.ie. [Revised on Feb 2018], Available at: https://www.hpra.ie/img/uploaded/swedocuments/2200075.PPA0465_439_001.8ff70424-403e-494c-a327-b60146c559ae.000001Product%20Leaflet%20Approved.180316.pdf (Accessed 07 June 2023).
- Package leaflet: Information for the user - Atenolol. www.hpra.ie. [Revised on June 2017], Available at: https://www.hpra.ie/img/uploaded/swedocuments/PIL-2194090-22062017180446-636337515623281250.pdf (Accessed 07 June 2023).
- Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Adrenergic agonists and Antagonists, 12th edition, 2011, 327.
- KD Tripathi, Essentials of Medical Pharmacology, Antiadrenergic drugs and glaucoma, 7th edition, 2013, 149.
The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.