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Written By
Sakshi Anil More
B. Pharm

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)

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AMLODIPINE,METOPROLOL
Last updated on 31 Mar 2026 | 09:30 AM (IST)
AMLODIPINE,METOPROLOL
Background and Date of approval AMLODIPINE,METOPROLOL
Amlodipine+Metoprolol is an antihypertensive agent. Amlodipine belongs to the group of medications called calcium channel blockers. Metoprolol belongs to the class of medications called beta-blockers.
Uses of AMLODIPINE,METOPROLOL
This fixed-dose combination is used to treat high blood pressure (hypertension). It is also used for heart-related chest pain, abnormal heart rhythms, and chronic (long-term) heart failure.
How is AMLODIPINE,METOPROLOL administered?
Amlodipine+Metoprolol is available as a tablet. Always use this medicine as exactly prescribed by your doctor. Depending on the condition being treated, your physician decides the dose, dosage, and duration of the treatment. Take the tablet at the same time every day, with or without food. Swallow the tablets with a glass of water. Do not break, crush, or chew the tablets.
Side Effects of AMLODIPINE,METOPROLOL
The most common side effects of amlodipine+metoprolol are headache, dizziness, tiredness, decreased heartbeat, decreased blood pressure, shortness of breath, stomach ache, diarrhea, constipation and indigestion, visual disturbances, muscle cramps, and ankle swelling. The other serious side effects are allergic reactions, heart attack, abnormal heart beat, severe abdominal and back pain.
Warnings
Do not take Amlodipine+metoprolol if you are allergic to amlodipine, metoprolol, or any of the other ingredients of this medicine. Do not take this medicine if you have severe asthma or severe attacks of wheezing. Do not consume this medicine if you have serious heart or blood vessel disorder, low blood pressure, if you have high blood pressure due to a tumor near your kidney, or if your blood is more acidic than normal (metabolic acidosis).
Precautions
Inform your physician if you recently had a heart attack or if you are suffering from a heart attack, severe increase in blood pressure, liver disease, lung disease, diabetes, and psoriasis before starting the therapy. Inform your physician if you are going to undertake any surgery or dental procedures while consuming these medicines. Consult your physician if you are pregnant or breastfeeding, or planning to get pregnant during the treatment.
Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, vaccines, nutritional or vitamin supplements, and herbal products. Certain medications may interact with amlodipine+metoprolol and reduce their effectiveness by causing undesirable side effects.
Word of Advice
If you forgot to take the tablet, take it as soon as you remember. However, skip the missed dose if it is nearly time for the next dose. Do not consume grapefruit or grapefruit juice. It is suggested to monitor your blood pressure regularly to prevent hypotension. You may also need regular eye examinations. Monitor your blood sugar levels regularly. Your doctor may suggest you to take certain tests to monitor the effectiveness and side effects of the therapy.
Frequently Asked Questions
Q1.
What are the common side effects of Amlodipine+metoprolol?
The most common side effects of amlodipine+metoprolol are headache, dizziness, tiredness, decreased heartbeat, decreased blood pressure, shortness of breath, stomach ache, diarrhea, constipation and indigestion, visual disturbances, muscle cramps, and ankle swelling.
Q2.
How long does it take for amlodipine + metoprolol to show its effects?
The time it takes for amlodipine + metoprolol to show its effects can vary from person to person. Generally, you may start noticing improvements in your blood pressure and cardiovascular symptoms within a few days to a few weeks of starting the medication. However, following your healthcare provider's instructions and continuing taking the medication as prescribed is important.
Q3.
Can amlodipine + metoprolol interact with herbal supplements?
Some herbal supplements may interact with amlodipine + metoprolol, potentially affecting their effectiveness or causing adverse effects. It's essential to inform your healthcare provider about any herbal supplements or alternative treatments you are taking to ensure safe and effective medication management.
Q4.
Can amlodipine + metoprolol cause weight gain?
Weight gain is not a common side effect of amlodipine + metoprolol. However, individual responses to medications may vary. If you notice any changes in your weight while taking this medication, it's recommended to discuss it with your healthcare provider.
Q5.
Can amlodipine + metoprolol be taken with food?
Amlodipine + metoprolol can be taken with or without food, as advised by your healthcare provider. However, it's a good practice to follow consistent instructions regarding food intake to ensure optimal medication absorption and effectiveness.
References
- Dr. Reddy’s Laboratories (UK) Ltd., Electronic Medicines Compendium (EMC) [Revised on July 2022] [Accessed on June 2023], https://www.medicines.org.uk/emc/product/3478/pil
- Zentiva Pharma UK Limited., Electronic Medicines Compendium (EMC) [Revised on April 2021] [Accessed on June 2023], https://www.medicines.org.uk/emc/files/pil.5200.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Antihypertensive Drugs, 7th Edition, 2018, 561-564.
Disclaimer
The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.






