This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Amlodipine+Metoprolol is an antihypertensive agent. Amlodipine belongs to the group of medications called calcium channel blockers. Metoprolol belongs to the class of medications called beta-blockers.

Mechanism of Action of undefined

Amlodipine and Metoprolol effectively reduce blood pressure. Amlodipine is a calcium channel blocker that relaxes blood vessels, whereas metoprolol is a beta blocker that works particularly on the heart to slow it down. They work together to improve the heart's efficiency in pumping blood throughout the body.

Uses of undefined

This fixed-dose combination is used to treat high blood pressure (hypertension). It is also used for heart-related chest pain, abnormal heart rhythms, and chronic (long-term) heart failure.

undefined Drug administaration and Dosage available

Amlodipine+Metoprolol is available as a tablet. Always use this medicine as exactly prescribed by your doctor. Depending on the condition being treated, your physician decides the dose, dosage, and duration of the treatment. Take the tablet at the same time every day, with or without food. Swallow the tablets with a glass of water. Do not break, crush, or chew the tablets.

Warnings, Precautions and Side Effects of undefined


Do not take Amlodipine+metoprolol if you are allergic to amlodipine, metoprolol, or any of the other ingredients of this medicine. Do not take this medicine if you have severe asthma or severe attacks of wheezing. Do not consume this medicine if you have serious heart or blood vessel disorder, low blood pressure, if you have high blood pressure due to a tumor near your kidney, or if your blood is more acidic than normal (metabolic acidosis).


Inform your physician if you recently had a heart attack or if you are suffering from a heart attack, severe increase in blood pressure, liver disease, lung disease, diabetes, and psoriasis before starting the therapy. Inform your physician if you are going to undertake any surgery or dental procedures while consuming these medicines. Consult your physician if you are pregnant or breastfeeding, or planning to get pregnant during the treatment.

Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, vaccines, nutritional or vitamin supplements, and herbal products. Certain medications may interact with amlodipine+metoprolol and reduce their effectiveness by causing undesirable side effects. 

Side Effects

The most common side effects of amlodipine+metoprolol are headache, dizziness, tiredness, decreased heartbeat, decreased blood pressure, shortness of breath, stomach ache, diarrhea, constipation and indigestion, visual disturbances, muscle cramps, and ankle swelling. The other serious side effects are allergic reactions, heart attack, abnormal heart beat, severe abdominal and back pain.

Word Of Advice

If you forgot to take the tablet, take it as soon as you remember. However, skip the missed dose if it is nearly time for the next dose.  Do not consume grapefruit or grapefruit juice. It is suggested to monitor your blood pressure regularly to prevent hypotension.  You may also need regular eye examinations. Monitor your blood sugar levels regularly. Your doctor may suggest you to take certain tests to monitor the effectiveness and side effects of the therapy.

Frequently Asked Question


  1. Dr. Reddy’s Laboratories (UK) Ltd., Electronic Medicines Compendium (EMC) [Revised on July 2022] [Accessed on June 2023],
  2. Zentiva Pharma UK Limited., Electronic Medicines Compendium (EMC) [Revised on April 2021] [Accessed on June 2023],
  3. KD Tripathi, Essentials of Medical Pharmacology, Antihypertensive Drugs, 7th Edition, 2018, 561-564.


The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.