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Written By
P. Thirumal Reddy
B. Pharm

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)

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AMOXYCILLIN,CLAVULANIC ACID
Last updated on 31 Mar 2026 | 09:30 AM (IST)
AMOXYCILLIN,CLAVULANIC ACID
Background and Date of approval AMOXYCILLIN,CLAVULANIC ACID
The U.S. FDA-approved Amoxicillin, Clavulanic Acid, to treat people with bacterial infection in 1984.
Uses of AMOXYCILLIN,CLAVULANIC ACID
Amoxicillin, Clavulanic Acid, is used to treat bacterial infections such as sinus and middle ear infections, respiratory tract infections, urinary tract infections (UTI), soft tissue and skin infections, including dental infections, bone, and joint infections.
How is AMOXYCILLIN,CLAVULANIC ACID administered?
Amoxicillin, Clavulanic Acid Tablet
Amoxicillin is an orally administered drug. Take medicine as informed by your physician. It is usually taken with food. Swallow the tablets whole; do not split, chew, or crush them. Do not stop taking Amoxicillin without talking to your doctor. Your doctor will determine frequency and dosage based on your condition and severity.
Amoxicillin, Clavulanic Acid Injection
Amoxicillin injection is administered as an intravenous infusion of intravenous injection into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.
Amoxicillin, Clavulanic Acid Syrup, And Oral Suspension
Shake well before taking Amoxicillin oral suspension. If this oral suspension is recommended for you, your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.
Side Effects of AMOXYCILLIN,CLAVULANIC ACID
The most common side effects of Amoxicillin, Clavulanic Acid are fever, joint pain, swelling in the neck, groin, or armpit angioedema (swelling of face or throat), difficulty in breathing, diarrhea
Serious side effects while taking Amoxicillin, and Clavulanic Acid is allergic reactions such as skin rash and blood vessel inflammation (red or purple spots), hyperactivity, decrease in white blood cell count.
Warnings
Notify your doctor if you have a history of a liver disorder or any liver-related condition. Your doctor will regularly monitor the liver test for liver functioning. Before starting the treatment, notify your doctor if you have had or have had a history of hypersensitivity (swelling in the face or throat and skin rashes) or jaundice. Certain medications such as Allopurinol, Probenecid, Warfarin, Methotrexate, and Mycophenolate mofetil may interact with Amoxicillin and reduce effectiveness by causing undesirable side effects. So inform your doctor if you take any other medications. Report to your doctor if you have or have a history of glandular fever, took treatment for liver or kidney problems, or have less urination.
Precautions
Inform your physician if you experience allergic reactions to Amoxicillin, Clavulanic Acid. Before starting the treatment, inform your doctor if you are pregnant or think you may be pregnant or are planning to have a baby because your physician shall prescribe Amoxicillin, and Clavulanic Acid only if it is essential. Consult your doctor for more information. Inform your doctor if you are under a controlled potassium diet or with reduced kidney function. Notify your doctor if you are planning to have a blood test related to RBC status, liver function test, or urine test because this medicine can affect the result of these tests. Notify your doctor if you take or take any other medicine. Underlying kidney conditions, patients should avoid discussion about dose alteration.
Word of Advice
Do not consume this syrup if you are allergic to Amoxicillin, Clavulanic acid, Penicillins, or any of the other ingredients of this medicine. Do not store above 25°C If you missed a dose, do not take a double dose for the forgotten dose. If you have overdosed on Amoxicillin syrups or someone accidentally takes your syrup, contact the hospital or a doctor immediately for medical advice.
Frequently Asked Questions
Q1.
Are there any serious side effects of amoxicillin?
Serious side effects are rare, but they can occur. These include severe allergic reactions, liver damage, or a decrease in white blood cell count.
Q2.
How does the combination of amoxicillin work?
Amoxicillin is a penicillin-type antibiotic that works by stopping the growth of bacteria, while clavulanic acid extends the spectrum of amoxicillin's antibacterial activity and helps to prevent bacterial resistance.
Q3.
Can I still take amoxicillin if I have had a previous allergic reaction to penicillin?
If you have had a previous allergic reaction to penicillin, it's essential to inform your healthcare provider before starting treatment with amoxicillin Depending on the severity of your allergic reaction, your doctor may recommend an alternative medication.
Q4.
What should I do if I experience side effects?
If you experience any side effects, contact your healthcare provider immediately. Sometimes, they may advise you to stop taking the medication or switch to a different medication.
Q5.
Can amoxicillin be taken during pregnancy or breastfeeding?
Amoxicillin can be taken during pregnancy or breastfeeding, but it's important to consult with a healthcare provider before taking any medication.
References
- KD Tripathi. Beta-Lactam Antibiotics, Essentials of medical pharmacology. Seventh edition, 2013, 723.
- Brown &Burk UK Ltd, Electronic medicines compendium (EMC), [Revised on Aug 2022], [Access on 15th April 2023] https://www.medicines.org.uk/emc/product/4078/smpc
Disclaimer
The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.






