This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

The U.S. FDA-approved Amoxicillin, Clavulanic Acid, to treat people with bacterial infection in 1984.

Mechanism of Action of undefined

Amoxicillin combines two medicines (Amoxycillin and Clavulanic Acid). Amoxycillin (antibiotic) is a penicillin that helps treat bacterial infection by preventing the formation of the structural component of bacteria, which is essential for the survival of bacteria. Clavulanic Acid is a beta-lactamase inhibitor that works by reducing the activity of enzymes and preventing the inactivation of Amoxycillin against bacteria.

Uses of undefined

Amoxicillin, Clavulanic Acid, is used to treat bacterial infections such as sinus and middle ear infections, respiratory tract infections, urinary tract infections (UTI), soft tissue and skin infections, including dental infections, bone, and joint infections.

undefined Drug administaration and Dosage available

Amoxicillin, Clavulanic Acid Tablet

Amoxicillin is an orally administered drug. Take medicine as informed by your physician. It is usually taken with food. Swallow the tablets whole; do not split, chew, or crush them. Do not stop taking Amoxicillin without talking to your doctor. Your doctor will determine frequency and dosage based on your condition and severity. 

Amoxicillin, Clavulanic Acid Injection 

Amoxicillin injection is administered as an intravenous infusion of intravenous injection into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.

Amoxicillin, Clavulanic Acid Syrup, And Oral Suspension 

Shake well before taking Amoxicillin oral suspension. If this oral suspension is recommended for you, your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.

Warnings, Precautions and Side Effects of undefined

Warnings

Notify your doctor if you have a history of a liver disorder or any liver-related condition. Your doctor will regularly monitor the liver test for liver functioning. Before starting the treatment, notify your doctor if you have had or have had a history of hypersensitivity (swelling in the face or throat and skin rashes) or jaundice. Certain medications such as Allopurinol, Probenecid, Warfarin, Methotrexate, and Mycophenolate mofetil may interact with Amoxicillin and reduce effectiveness by causing undesirable side effects. So inform your doctor if you take any other medications. Report to your doctor if you have or have a history of glandular fever, took treatment for liver or kidney problems, or have less urination. 

Precautions

Inform your physician if you experience allergic reactions to Amoxicillin, Clavulanic Acid. Before starting the treatment, inform your doctor if you are pregnant or think you may be pregnant or are planning to have a baby because your physician shall prescribe Amoxicillin, and Clavulanic Acid only if it is essential. Consult your doctor for more information. Inform your doctor if you are under a controlled potassium diet or with reduced kidney function. Notify your doctor if you are planning to have a blood test related to RBC status, liver function test, or urine test because this medicine can affect the result of these tests. Notify your doctor if you take or take any other medicine. Underlying kidney conditions, patients should avoid discussion about dose alteration.

Side Effects

The most common side effects of Amoxicillin, Clavulanic Acid are fever, joint pain, swelling in the neck, groin, or armpit angioedema (swelling of face or throat), difficulty in breathing, diarrhea

Serious side effects while taking Amoxicillin, and Clavulanic Acid is allergic reactions such as skin rash and blood vessel inflammation (red or purple spots), hyperactivity, decrease in white blood cell count.

Word Of Advice

Do not consume this syrup if you are allergic to Amoxicillin, Clavulanic acid, Penicillins, or any of the other ingredients of this medicine. Do not store above 25°C If you missed a dose, do not take a double dose for the forgotten dose.  If you have overdosed on Amoxicillin syrups or someone accidentally takes your syrup, contact the hospital or a doctor immediately for medical advice.

Frequently Asked Question

References

  1. KD Tripathi. Beta-Lactam Antibiotics, Essentials of medical pharmacology. Seventh edition, 2013, 723.
  2. Brown &Burk UK Ltd, Electronic medicines compendium (EMC), [Revised on Aug 2022], [Access on 15th April 2023] https://www.medicines.org.uk/emc/product/4078/smpc 

Disclaimer

The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.