Uses of undefined

Bendamustine is an alkylating agent used in the treatment of Chronic lymphocytic leukaemia(cancer of blood and bone marrow), Non-Hodgkin’s lymphomas(cancer that forms in the lymph system, part of the immune system), and Multiple myeloma(cancer of plasma cells, type of white blood cell).

undefined Drug administaration and Dosage available

Bendamustine is a prescription drug available in injection form. This injection will be given intravenously into a vein in your arm or hand by a healthcare professional in a hospital setting. Do not self-administer this medicine. Treatment should not be started if your white blood cells (leukocytes) have fallen to counts below determined levels. Your doctor will determine these values at regular intervals. The dose of the injection will be decided by your doctor based on your disease condition and other factors. Bendamustine Injection is usually given about 30 minutes before you receive your anti-cancer medicine (chemotherapy) or right before anaesthesia for surgery. During the infusion, you will be monitored for any side effects or reactions to the medication. The infusion usually takes several hours to complete, and you may need to receive multiple infusions over the course of several weeks.

Warnings, Precautions and Side Effects of undefined

Warnings

Bendamustine is not recommended in patients who have hypersensitivity reactions. This medicine may cause allergic reactions in some people. Symptoms of an allergic reaction include itching, difficulty breathing, swelling of the face or throat, and a rapid heartbeat. If you experience any of these symptoms, consult your doctor immediately. Bendamustine is contraindicated in women who are or may become pregnant during therapy. It may cause fetal harm when administered to a pregnant woman. This medicine should be avoided in patients with severe immunosuppression due to bone marrow suppression.

Precautions

Suppressed bone marrow function may lead to low blood cells, which in turn may lead to an increased risk of infection, anaemia or excess bleeding. Your doctor will monitor your blood counts regularly during treatment and may adjust the dosage or frequency of administration if necessary. If you plan to father a child, you should avoid fathering a child during treatment with Bendamustine for infusion and for up to 6 months after treatment has stopped. There may be an increased risk of certain types of skin cancer (non-melanoma skin cancer) with the use of this medicine. Consult your doctor immediately for more advice.

Side Effects

The common side effects that are likely to occur with this medicine are headache, insomnia, fatigue, loss of appetite and rashes. Other serious side effects also include myelosuppression, tumor lysis syndrome, and hepatotoxicity. Inform your healthcare provider if these side effects concern you or persist for longer than usual.

Word Of Advice

Bendamustine can cause harm to a developing fetus or nursing baby, so it is important to discuss contraception options and the need to avoid breastfeeding during treatment. This drug causes fatigue, so encourage the patient to take enough rest and self-care during treatment. Avoid driving or operating heavy machines if you experience dizziness, nausea or tiredness while on treatment with Bendamustine. It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose. Store Bendamustine injection in the refrigerator (2°-8°C). Do not freeze. Keep it out of reach from children. This drug increases the risk of bleeding and bruising, so it is important to be careful when using sharp objects or participating in activities that may result in injury.

Frequently Asked Question

• What is Bendamustine used for?
• Bendamustine is a chemotherapy drug used to treat various types of cancers, including non-Hodgkin's lymphoma, chronic lymphocytic leukaemia, and multiple myeloma.

• How will I receive Bendamustine Injection?
• Bendamustine solution is administered into a vein as a short-term infusion over 30 – 60 minutes.

• How does bendamustine work to treat cancer?
• Bendamustine works by damaging the DNA in cancer cells, preventing them from multiplying and spreading.

• Can bendamustine be used in combination with other drugs?
• Yes, bendamustine is often used in combination with other chemotherapy drugs to improve treatment outcomes.

• Whether Bendamustine is safe to use during pregnancy?
• Bendamustine is not recommended during pregnancy and it is unsafe because it may harm a developing fetus. Women who are pregnant or planning to become pregnant should discuss their treatment options with their doctor immediately.

• Who should not take a Bendamustine?
• Bendamustine should not be taken by individuals who are allergic to it or its ingredients.