This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Biapenem contains the active component Biapenem. It is a broad-spectrum antibiotic medication used to treat various bacterial infections. It belongs to the class of antibiotics known as third-generation cephalosporins. This medication works by inhibiting the growth and reproduction of bacteria, helping the immune system eliminate the infection. Biapenem is effective against both gram-positive and gram-negative bacteria.

Mechanism of Action of undefined

Biapenem exerts a therapeutic effect by inhibiting the growth and spread of bacterial infections. As a broad-spectrum carbapenem antibiotic, it demonstrates potent activity against many Gram-positive and Gram-negative bacteria. By binding to specific bacterial enzymes called penicillin-binding proteins (PBPs), this medication disrupts the synthesis of the bacterial cell wall, leading to cell lysis and death. Its broad coverage makes it effective against various multidrug-resistant bacteria, offering a valuable treatment option in severe or complicated infections.

Uses of undefined

Biapenem is indicated for complicated intra-abdominal infections, urinary tract infections, and pneumonia. It also treats complicated skin and soft tissue infections, including diabetic foot infections. Its effectiveness against multidrug-resistant bacteria makes it a valuable option in healthcare-associated and nosocomial infections.

undefined Drug administaration and Dosage available

Biapenem is typically administered through injection by a healthcare professional. The dosage and duration of treatment depend on the specific infection being treated, the severity of the infection, and individual patient factors such as age and overall health.

Warnings, Precautions and Side Effects of undefined


Biapenem carries important warnings that should be considered before use. These include the risk of severe hypersensitivity reactions, such as anaphylaxis, the potential development of Clostridioides difficile infection resulting in severe diarrhea and colitis, and the possibility of superinfection with resistant bacteria or fungi.


When using Biapenem, taking special caution in patients with renal impairment, a history of seizures, and during pregnancy and breastfeeding is important. It is crucial to be aware of these warnings and consult a healthcare professional for appropriate guidance and monitoring during treatment.

Side Effects

Biapenem can cause side effects varying in severity and frequency. Common side effects may include gastrointestinal disturbances like nausea, vomiting, diarrhea, abdominal pain, and skin reactions such as rashes, itching, or hives. Headaches and injection site reactions such as pain, swelling, or redness can also occur. Serious side effects, although rare, may include allergic reactions such as anaphylaxis, seizures, and changes in liver function.

Word Of Advice

Regarding your health and medication usage, it is important to prioritize open communication with your healthcare provider. Make sure to provide them with a comprehensive overview of your medical history, including any existing conditions, medications you are currently taking, or any allergies you may have. Elderly individuals may be more sensitive to the effects of Biapenem. Monitor if you see any infusion-related problems. Age-related changes in metabolism reduce cardiac reserve, and other factors can increase the risk of adverse reactions. Close monitoring and appropriate dose adjustments are necessary for the elderly. Individuals with liver or kidney impairment should be closely monitored during treatment. Pregnant and breastfeeding women should consult a doctor before taking it. Lastly, use caution in pediatric patients and discuss the potential risks and benefits with a healthcare professional.

Frequently Asked Question


  1. Sanford Guide, The Medical Management of Infectious Diseases, 7th Edition. Year 2022, 1100-1101
  2. Caroline M Perry; Biapenem; Drugs; [Published on 2002]; [Accessed on 8th June 2023],
  3. Amit Kaushik et al.; In vitro and in vivo activity of biapenem against drug-susceptible and rifampicin-resistant Mycobacterium tuberculosis; Journal of Antimicrobial Chemotherapy; [Published on 01/06/2017]; [Accessed on 8/06/2023];


The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.