Available Brands

Did you find this information helpful?

Author Details

Written By

Sakshi Anil More

B. Pharm

Reviewed By

Dr. Tejashwin Adiga

MBBS

Last updated : 18 May 2026 | 08:49 AM (IST)

Want to know more?
Read Our Editorial Policy

Quick Summary

BICTEGRAVIR,EMTRICITABINE,TENOFOVIR ALAFENAMIDE

Written By:Sakshi Anil MoreB. Pharm Reviewed By:Dr. Tejashwin AdigaMBBS

Last updated on 18 May 2026 | 08:49 AM (IST)

BICTEGRAVIR,EMTRICITABINE,TENOFOVIR ALAFENAMIDE

Background and Date of approval BICTEGRAVIR,EMTRICITABINE,TENOFOVIR ALAFENAMIDE

Bictegravir, Emtricitabine and Tenofovir Alafenamide is a combination regimen consisting of antiviral medications, which was approved for its medical use on 7th February 2018.

Uses of BICTEGRAVIR,EMTRICITABINE,TENOFOVIR ALAFENAMIDE

Bictegravir, Emtricitabine and Tenofovir Alafenamide has been developed to treat Human Immunodeficiency Virus (HIV-1). Bictegravir, Emtricitabine and Tenofovir Alafenamide Tablet is indicated as a complete regimen for treating adults and children weighing at least 14kg infected with HIV 1.

How is BICTEGRAVIR,EMTRICITABINE,TENOFOVIR ALAFENAMIDE administered?

Bictegravir, Emtricitabine and Tenofovir Alafenamide is available as film coated tablets consisting of 50mg of Bictegravir, 200mg of Emtricitabine and 25mg of Tenofovir Alafenamide. The usual recommended dosage of this combination regimen is one tablet everyday with or without food.

Side Effects of BICTEGRAVIR,EMTRICITABINE,TENOFOVIR ALAFENAMIDE

The common side effects that are likely to occur while you are on the treatment with Bictegravir, Emtricitabine and Tenofovir Alafenamide Tablet are diarrhoea, nausea and headache. Some serious adverse reactions include bone loss, worsening of Hepatitis B, kidney injury, immune reconstitution syndrome, lactic acidosis and liver toxicity. If you experience any allergic reactions after taking this tablet, report to your doctor immediately.

Warnings

Do not take this medication if you have experienced hypersensitivity reactions to Bictegravir, Emtricitabine or Tenofovir Alafenamide. Patients who are diagnosed with pancreatitis or at risk of pancreatitis should take this combination medicine with caution. During the Bictegravir, Emtricitabine and Tenofovir Alafenamide Tablet treatment, your doctor may periodically monitor your blood counts, bone mineral density, liver and kidney parameters to prevent serious complications. Report to your doctor if you have had a history of heart failure, pancreatitis, bone disease, fractures, liver or kidney problems.

Precautions

Adults of childbearing potential should consider using an effective contraceptive to prevent unwanted pregnancy. If you are pregnant or think you might be pregnant, your physician might suggest an alternative treatment as this combination regimen is not recommended during early pregnancy. Breastfeeding is not recommended due to potential transmission of HIV from mother to the baby.

Word of Advice

Avoid driving or handling machines during this treatment if you feel dizzy or tired.

Frequently Asked Questions

Q1.

What should you not take with Bictegravir, Emtricitabine and tenofovir Alafenamide?

It is not recommended to take Bictegravir, Emtricitabine and tenofovir Alafenamide tablet with antacids. Tell your healthcare provider if you are taking any other medications, over-the counter drugs, vitamin or herbal supplements.

Q2.

How to take Bictegravir, Emtricitabine and Tenofovir Alafenamide Tablet if you have difficulty swallowing?

If you have problems with swallowing, split the tablet into two and take them separately within 10 minutes.

Q3.

How to store Bictegravir, Emtricitabine, Tenofovir Alafenamide Tablets?

Store Bictegravir, Emtricitabine, Tenofovir Alafenamide tablets at room temperature in a tightly closed container, away from the reach of children.

Q4.

What are the required laboratory parameters prior to starting this treatment?

If you are an adolescent or adult of childbearing potential, your healthcare provider will perform pregnancy test before prescribing this treatment. other prominent tests include test for HBV infection, serum creatinine, estimated creatinine clearance, urine glucose and urine protein.

Q5.

What should you do if you miss a dose of Bictegravir, Emtricitabine and Tenofovir Alafenamide Tablet?

If you missed a dose of Bictegravir, Emtricitabine and Tenofovir Alafenamide Tablet, take one tablet as soon as you remember. However, if it is almost time for your next dose, skip this dose and take your next dose as per schedule. Do not take two doses to compensate for the missed dose.

Q6.

What are some of the long-term side effects of this combination regimen?

Some serious side effects of this combination regimen include worsening of hepatitis B, bone loss, kidney injury, pancreatitis, immune reconstitution syndrome, liver toxicity and hypersensitivity reactions.

Q7.

What are the symptoms of lactic acidosis?

Unusual weakness, tiredness, muscle pain, trouble breathing, stomach pain, nausea, vomiting, dizziness, lightheadedness, irregular heartbeat and feeling cold especially in your arms and legs are the most prominent symptoms of lactic acidosis.

References

KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
Gilead Sciences Inc., U.S. Food and Drug Administration, [Revised on Oct 2021] [Accessed on 7th Oct 2022], https://www.gilead.com/-/media/files/pdfs/medicines/hiv/biktarvy/biktarvy_pi.pdf

Disclaimer

The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.

;