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BISOPROLOL

BISOPROLOL

Background and Date of approval BISOPROLOL

Bisoprolol is an Anti-Hypertensive drug that belongs to the category of medicines known as beta1-selective adrenoceptor-blocking agents. It was approved by the U.S. FDA in 1986 to treat hypertension, angina pectoris, and chronic heart failure.

Uses of BISOPROLOL

Bisoprolol has been approved to treat hypertension (high blood pressure), angina pectoris (chest pain), and chronic heart failure.

How is BISOPROLOL administered?

The recommended initial dose of Bisoprolol is 5mg per day. The usual dosage is 10 mg once daily, with a maximum daily dose of 20 mg. Follow your doctor's instructions exactly. It should be taken in the morning with food. Swallow the tablets as a whole with water. Do not crush, chew or break it.

Side Effects of BISOPROLOL

The common side effects that are likely to occur while you are on the treatment with Bisoprolol are dizziness, nausea, vomiting, diarrhea, constipation, headache, bradycardia, asthenia, fatigue, hypotension, coldness, or numbness in the extremities. Inform your healthcare professional if these side effects disturb you or persist. Report to your doctor immediately if you have a slow heart rate, worsening of heart failure (increased breathlessness and swelling of legs), dizziness, weakness, breathing difficulty, and allergic reaction like swelling of the face, mouth, or throat and muscle coordination problems.

Warnings

Contact your physician immediately if you experience allergies to Bisoprolol and its ingredients. Inform your physician if you have kidney or liver conditions. While taking this medicine, your doctor monitors blood pressure levels. Before taking this medication, let your medical professional know if you have a medical history of severe asthma or chronic lung disease, slow or irregular heart rate, heart failure, cardiogenic shock, metabolic acidosis, or untreated pheochromocytoma.

Precautions

Consult your doctor before using this medication if you are pregnant or planning to have a baby. Bisoprolol tablets should not be taken while pregnant unless specifically advised by your doctor. If this medication is required in pregnancy, the uteroplacental blood flow and fetal growth should be closely monitored. Avoid breastfeeding your baby while on the treatment, as it is not known whether Bisoprolol passes into the breastmilk and affects the baby.

Word of Advice

It is advised to monitor your blood pressure regularly to prevent hypotension (low blood pressure). If you ever fainted or felt dizzy when suddenly standing up, consult your doctor before taking this medication. Do not skip doses without consulting your physician, as it may increase blood pressure and increase the chance of a heart attack.

Frequently Asked Questions

Q1.

Does Bisoprolol reduce blood pressure?

Yes, Bisoprolol lowers blood pressure. Consult your physician if you experience any unpleasant symptoms, such as headache, sweating, or dizziness. 

Q2.

What should you do if you overdose on Bisoprolol?

Report to your physician immediately if you overdose on Bisoprolol, as it may cause some adverse effects like bradycardia, hypotension, bronchospasm, acute cardiac insufficiency, and hypoglycemia.

Q3.

Can I stop taking Bisoprolol if I feel better?

No, even if you feel better, keep taking Bisoprolol until the end of the recommended course of treatment. Your doctor will gradually reduce the dose. Sudden withdrawal of this medication increases the risk of heart attack and stroke.

Q4.

What tests do you need to undergo during treatment with Bisoprolol?

During treatment with Bisoprolol, your healthcare provider will monitor your blood pressure regularly.

Q5.

What is the best time to take Bisoprolol?

Bisoprolol can be taken anytime in the morning, generally prescribed once daily. It can be taken with food. Hence, it is advised to take it on the same day. 

Q6.

Can I drink alcohol while taking Bisoprolol?

No, Drinking alcohol can increase the blood pressure-lowering effect of bisoprolol, leading to dizziness or lightheadedness.

References

  1. KD Tripathi, Essentials of Medical Pharmacology, Cardiac glycosides and Drugs for heart failure, 7th Edition, 2013, 523-526.
  2. Duramed Pharmaceuticals Inc., US Food and Drug Administration, [ Revised on May 2007] [ Accessed on 2 nd November 2022],https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/019982s014lbl.pdf
  3. Accord Healthcare Limited; Electronic Medicines Compendium (EMC), [Revised on January 2022] [Accessed on 2 nd November 2022], https://www.medicines.org.uk/emc/product/6126/smpc#gref

Disclaimer

The drug information on this page is not a substitute for medical advice; it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.

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