This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Bromocriptine was approved by the U.S. Food and Drug Administration (FDA) for medical use on October 19, 1978.
Mechanism of Action of undefined
Bromocriptine exerts its therapeutic effect as a dopamine agonist, activating dopamine receptors in the brain. This results in regulating dopamine levels and leads to various beneficial outcomes. This medication lowers prolactin levels in hyperprolactinemia, alleviating associated symptoms like irregular menstrual periods and infertility. For Parkinson's disease, it improves motor symptoms by compensating for dopamine deficiency.
In acromegaly, it reduces growth hormone levels, mitigating abnormal tissue growth. It can also manage neuroleptic malignant syndrome emergencies. While occasionally used off-label, it may help improve glycemic control in patients with type 2 diabetes. These diverse therapeutic effects make this medication valuable in treating various medical conditions related to dopamine imbalance.
Uses of undefined
Bromocriptine is used to treat hyperprolactinemia, Parkinson's disease, and acromegaly, and it can be considered for other conditions like neuroleptic malignant syndrome and type 2 diabetes (off-label).
undefined Drug administaration and Dosage available
Bromocriptine should be taken exactly as prescribed by a healthcare professional. It is available in various forms, such as tablets or capsules. The dosage and frequency depend on the medical condition being treated. This medication can be taken with or without food, and patients should not adjust the dosage or stop taking it without medical guidance. Adherence to the prescribed schedule is crucial, and any potential side effects should be promptly reported to the healthcare provider.
Warnings, Precautions and Side Effects of undefined
Warnings
Bromocriptine comes with several important warnings. It may cause cardiovascular effects, including changes in blood pressure, and may lead to psychiatric side effects such as hallucinations and confusion. Some patients may experience impulse control disorders. As an ergot derivative, Bromocriptine carries a risk of ergotism.
Precautions
Patients with liver dysfunction should be cautious due to potential changes in drug clearance. It should not be used during the early postpartum period or in women with certain pregnancy-related conditions. The medication is generally not recommended during breastfeeding. Bromocriptine may interact with other medications and substances. Caution is advised when driving or operating machinery due to potential dizziness or drowsiness. Patients should be aware of the signs of allergic reactions and seek immediate medical attention if they occur.
Side Effects
Bromocriptine may cause various side effects, including nausea, vomiting, headache, dizziness, fatigue, and abdominal discomfort. It can also lead to changes in blood pressure, lowering and raising it, and may result in psychiatric effects such as hallucinations and confusion.
Word Of Advice
Patients with cardiovascular disorders, such as a history of heart disease or uncontrolled hypertension, require close monitoring due to potential blood pressure changes. Patients with a history of psychiatric disorders or impulse control issues should be closely monitored for any exacerbation of symptoms. Caution is advised in patients with liver dysfunction, as dosage adjustments may be necessary. The medication should not be used during the early postpartum period or in women with certain pregnancy-related conditions. Breastfeeding should generally be avoided while using Bromocriptine. If patients experience allergic reactions or any concerning symptoms, immediate medical attention should be sought. Your health is invaluable, and taking a proactive and informed approach to your well-being is crucial for a happy and fulfilling life.
Frequently Asked Question
References
- Mylan Pharma; Electronic Medicines Compendium; [Revised: 11 Mar 2022] [Accesses: 20/July/2023]; https://www.medicines.org.uk/emc/files/pil.11939.pdf
- VeroScience, LLC Ltd; FDA (Food and Drug Safety Administration); [Revised on: September 2010] [Accessed: 20/July/2023]; https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020866s006s007lbl.pdf
Disclaimer
The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.