This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Calcitriol was initially approved by the United States Food and Drug Administration (FDA) on October 21, 1998.

Mechanism of Action of undefined

Calcitriol, the active form of vitamin D, exerts significant therapeutic effects on calcium and phosphate regulation, bone health, and kidney function. Enhancing calcium and phosphate absorption from the intestines, it maintains optimal mineral levels in the blood, which is crucial for bone strength, nerve transmission, and muscle function. Its collaboration with parathyroid hormone ensures proper calcium balance, while its role in preventing excessive urinary calcium loss preserves renal function. These combined actions make this medication indispensable in treating conditions like hypoparathyroidism, renal osteodystrophy, and vitamin D deficiency, contributing to overall skeletal integrity and mineral homeostasis.

Uses of undefined

Calcitriol  is used to manage conditions related to calcium and bone metabolism. It is prescribed for treating low blood calcium levels, addressing disorders like hypoparathyroidism, supporting bone health in chronic kidney disease, managing osteoporosis, addressing conditions like rickets and osteomalacia, and sometimes it helps in psoriasis treatment. 

undefined Drug administaration and Dosage available

Calcitriol  can be administered through oral ingestion as capsules or liquid, and intravenous injection. The exact dosage and treatment duration will depend on instructions provided by a healthcare professional.

Warnings, Precautions and Side Effects of undefined


Calcitriol  use include the risk of hypercalcemia (high blood calcium levels), which can lead to serious health issues like kidney stones and cardiac abnormalities.  Long-term use might affect bone health, and liver function could impact its metabolism.  Allergic reactions like rash, swelling, or breathing difficulties are also possible. Excessive amounts of diet can impact the effects of this medication.


Monitoring calcium levels is essential. Calcitriol  should be used cautiously in patients with impaired kidney function and always vonsult the health care provuder for dosage adjustments. Individuals with lung conditions like sarcoidosis also require monitoring by the health care provider due to potential effects on calcium levels. Allergic reactions are possible, so seek medical attention if you experience rash, swelling, or breathing difficulties. Pregnant and breastfeeding individuals should consult their doctors before using this medication.

Side Effects

Calcitriol  can cause various side effects. Common side effects include increased thirst, loss of appetite, nausea, vomiting, constipation, muscle weakness, headache, and dry mouth. Serious side effects can include hypercalcemia (elevated blood calcium levels), allergic reactions with rash and difficulty breathing, kidney stone formation, irregular heartbeat, and bone pain.

Word Of Advice

Consult a healthcare professional before starting Calcitriol, especially if you are pregnant or breastfeeding mother. Take the amount your doctor recommends and follow the directions. Be careful if you are taking blood thinners, blood pressure medications, or cholesterol drugs.  Serious reactions like allergies, tummy troubles, or low blood pressure are rare but possible. If allergic reactions they happen, stop using it and see a doctor. Keep checking in with your doctor, especially if you might get a little upset stomach, headache, diarrhea, or trouble sleeping. They will help you decide if you still need to take it. Before starting this medication, tell your doctor about your health history and other supplements.

Frequently Asked Question


  1. Hospira, Inc., US Food & Drug Administration, [Revised on 03/2012] [Accessed on 21st August 2023],
  2. Atnahs Pharma UK Ltd, EMC [Revised on 02 Sep 2021] [Accessed on 21st August 2023]


The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.