This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Calcium Polystyrene Sulphonate are potassium binders which was approved for its medical use in the year 1958.

Mechanism of Action of undefined

When suspension is ingested, it passes through the stomach and enters the small intestine, where it starts to exchange sodium ions for potassium ions. It effectively removes excess potassium from the body. The exchange process occurs primarily in the colon, where the concentration of potassium is highest. By removing excess potassium from the body, It helps to prevent the complications associated with hyperkalemia.

Uses of undefined

Calcium Polystyrene Sulphonate has been developed to treat hyperkalemia (a condition where there is an excessive amount of potassium in the blood) associated with anuria or severe oliguria.

undefined Drug administaration and Dosage available

Calcium polystyrene sulphonate is an oral suspension. The dose and frequency of administration will be decided by your doctor based on your disease condition and other factors. Take medicine as directed by your physician. Take it with or without food. The chances of stomach upset are less if you take this suspension with food. Oral suspension is prescribed when the patient cannot swallow the tablet form of this medicine. The recommended dose is based on the individual’s body weight. It is important to complete the whole course, even if you start to feel better quickly.

Warnings, Precautions and Side Effects of undefined


Oral administration of this suspension is contraindicated in neonates. This is because neonates have an immature gastrointestinal system and reduced gut motility, which can increase the risk of gastrointestinal complications such as intestinal obstruction and perforation. Magnesium containing laxatives should not be used along with this suspension. Caution is required if you are allergic to this suspension or any of its ingredients, also it should be avoided if you have an intestinal obstruction, thyroid problems, or high blood calcium levels. Get immediate medical attention if you experience itching, vision changes, confusion or dizziness.


Taking too much of this suspension may reduce the potassium levels in your blood below the normal level, and result in symptoms like muscle weakness, feel so irritable and confused. This suspension should be used with caution and only under the supervision of a healthcare professional, as it may worsen these conditions or interact with other medications used to treat them.

Side Effects

The common side effects that are likely to occur while you are on the treatment with Calcium Polystyrene Sulphonate  are constipation, nausea, vomiting, tiredness, weakness, excessive thirst, and frequent urination. Other serious side effects include stomach irritation, bowel obstruction and severe allergic reactions like rash and itching.

Word Of Advice

Your doctor may suggest tests for regular monitoring of your electrolyte level during treatment with this medicine. Shake the oral suspension before every use. It is recommended to avoid taking this suspension in a larger or smaller quantity than prescribed by your doctor. This suspension should not be taken with other medications or supplements, as it can result in serious side effects. It is important to avoid foods that are high in potassium such as bananas, oranges, tomatoes, spinach, nuts, dark chocolates, and salted foods, as they can interact with the medication and increase the risk of hyperkalemia. During the suspension intake, it is necessary to sit up properly while taking the medicine so that you do not suffocate when you swallow it.

Frequently Asked Question


  1. Resonium calcium (calcium polystyrene sulfonate) - sanofi. Available at: (Accessed on April 15, 2023).
  2. HPRA.IE- (Accessed on April 15, 2023).


The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.