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Written By
Sakshi Anil More
B. Pharm

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 23 Jun 2026 | 07:03 AM (IST)

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CALCIUM POLYSTYRENE SULPHONATE
Last updated on 23 Jun 2026 | 07:03 AM (IST)
CALCIUM POLYSTYRENE SULPHONATE
Background and Date of approval CALCIUM POLYSTYRENE SULPHONATE
Calcium Polystyrene Sulphonate are potassium binders which was approved for its medical use in the year 1958.
Uses of CALCIUM POLYSTYRENE SULPHONATE
Calcium Polystyrene Sulphonate has been developed to treat hyperkalemia (a condition where there is an excessive amount of potassium in the blood) associated with anuria or severe oliguria.
How is CALCIUM POLYSTYRENE SULPHONATE administered?
Calcium polystyrene sulphonate is an oral suspension. The dose and frequency of administration will be decided by your doctor based on your disease condition and other factors. Take medicine as directed by your physician. Take it with or without food. The chances of stomach upset are less if you take this suspension with food. Oral suspension is prescribed when the patient cannot swallow the tablet form of this medicine. The recommended dose is based on the individual’s body weight. It is important to complete the whole course, even if you start to feel better quickly.
Side Effects of CALCIUM POLYSTYRENE SULPHONATE
The common side effects that are likely to occur while you are on the treatment with Calcium Polystyrene Sulphonate are constipation, nausea, vomiting, tiredness, weakness, excessive thirst, and frequent urination. Other serious side effects include stomach irritation, bowel obstruction and severe allergic reactions like rash and itching.
Warnings
Oral administration of this suspension is contraindicated in neonates. This is because neonates have an immature gastrointestinal system and reduced gut motility, which can increase the risk of gastrointestinal complications such as intestinal obstruction and perforation. Magnesium containing laxatives should not be used along with this suspension. Caution is required if you are allergic to this suspension or any of its ingredients, also it should be avoided if you have an intestinal obstruction, thyroid problems, or high blood calcium levels. Get immediate medical attention if you experience itching, vision changes, confusion or dizziness.
Precautions
Taking too much of this suspension may reduce the potassium levels in your blood below the normal level, and result in symptoms like muscle weakness, feel so irritable and confused. This suspension should be used with caution and only under the supervision of a healthcare professional, as it may worsen these conditions or interact with other medications used to treat them.
Word of Advice
Your doctor may suggest tests for regular monitoring of your electrolyte level during treatment with this medicine. Shake the oral suspension before every use. It is recommended to avoid taking this suspension in a larger or smaller quantity than prescribed by your doctor. This suspension should not be taken with other medications or supplements, as it can result in serious side effects. It is important to avoid foods that are high in potassium such as bananas, oranges, tomatoes, spinach, nuts, dark chocolates, and salted foods, as they can interact with the medication and increase the risk of hyperkalemia. During the suspension intake, it is necessary to sit up properly while taking the medicine so that you do not suffocate when you swallow it.
Frequently Asked Questions
Q1.
How to take Calcium Polystyrene Sulphonate?
Mix the suspension with water, as directed by your healthcare provider. Do not use other liquids, such as fruit juices or milk, as they may interfere with the effectiveness of Calcium Polystyrene Sulphonate. The suspension must be shaken well before each use to ensure that the drug particles are evenly distributed throughout the liquid.
Q2.
What is the role of Calcium Polystyrene Sulphonate?
The role of Calcium Polystyrene Sulphonate is that it can treat hyperkalemia to lower the level of potassium in the blood.
Q3.
When should I take Calcium Polystyrene Sulphonate?
It is typically taken several times a day, with meals or as directed by your physician. This suspension should not be taken with other medications or supplements, as it can result in serious side effects.
Q4.
What suspension is used to lower potassium levels?
Calcium polystyrene sulfonate is used to treat hyperkalemia (increased amounts of potassium in the body). It works by removing excess potassium from the body.
Q5.
What are the contraindications of Calcium Polystyrene Sulphonate?
Oral administration of Calcium Polystyrene Sulphonate is contraindicated in neonates. This is because neonates have an immature gastrointestinal system and reduced gut motility, which can increase the risk of gastrointestinal complications such as intestinal obstruction and perforation.
Q6.
What foods are advised to avoid with Calcium Polystyrene Sulphonate?
It is important to avoid foods that are high in potassium such as Bananas, oranges, tomatoes, spinach, nuts, dark chocolates and salted foods, as they can interact with the medication and increase the risk of hyperkalemia.
Q7.
What are all the strengths available for Calcium Polysterene Sulphonate?
It is available in strengths of 15 grams/60 mL and 30 grams/120 mL.
References
- Wang X, Chen D, Song X, Wang J, Zhang H. Efficacy and safety of calcium polystyrene sulfonate in patients with hyperkalemia and stage 3-5 non-dialysis chronic kidney disease: a single-centre randomized controlled trial. https://pmc.ncbi.nlm.nih.gov/articles/PMC10119845/
Disclaimer
The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.






