This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Calcium and vitamin D3 contain active ingredients such as calcium and vitamin D3. It is used to treat low levels of calcium. It can be given for certain bone conditions such as osteoporosis (thinning of bone) along with other medicines. Calcium is essential for developing and maintaining strong bones and teeth and properly functioning the heart, nerves, and muscles. 

Getting enough calcium through diet or supplements is important because the body cannot produce calcium alone. Vitamin D3, or cholecalciferol, is a fat-soluble vitamin that helps the body absorb and utilize calcium. Together, calcium and vitamin D3 work synergistically to promote healthy bones and teeth and to support other physiological processes in the body.

Mechanism of Action of undefined

The therapeutic effects of calcium and vitamin D3 are primarily related to their ability to support bone health and prevent or treat conditions such as osteoporosis, osteopenia, and rickets. Together, these nutrients strengthen bones, increase bone density, and reduce the risk of fractures.

Uses of undefined

Calcium and vitamin D3 supplements are useful in treating osteoporosis and osteopenia, which involve a loss of bone density and an increased risk of fractures. They are also used to treat hypocalcemia, a condition characterized by low calcium levels in the blood, and to support the development of healthy bones in children and adolescents. Other uses are chronic kidney disease, certain types of cancer, and postmenopausal women.

undefined Drug administaration and Dosage available

Calcium and vitamin D3 supplements are typically taken orally in tablets, capsules, or chewable tablets. The recommended dosage can vary depending on the condition being treated and other factors such as your overall health and response to treatment. Do not take a double dose to make up for a missed dose.

Warnings, Precautions and Side Effects of undefined


The calcium and vitamin D3 supplements may interact with certain medications, such as bisphosphonates, thyroid hormones, and certain antibiotics. High doses of calcium may lead to hypercalcemia, which can cause symptoms such as nausea, vomiting, constipation, and fatigue. They may increase the risk of kidney stones, and high calcium levels in the blood can harm the kidneys. There may be a slight increased risk of cardiovascular events.


It is important to inform your healthcare provider of all your medications. People with kidney disease should also exercise caution when taking calcium and vitamin D3 supplements, as high calcium levels in the blood can harm the kidneys. Finally, suppose you have a history of heart disease. In that case, talking to your healthcare provider before taking these supplements is important.

Side Effects

The common side effects of calcium and vitamin D3 supplements include constipation, nausea, vomiting, stomach upset, and increased thirst. The serious side effect is hypercalcemia, a condition with too much calcium in the blood. Symptoms of hypercalcemia may include nausea, vomiting, constipation, muscle weakness, confusion, and increased urination.

Word Of Advice

Suppose you are considering taking calcium and vitamin D3 supplements. In that case, it is important to consult with a healthcare professional to determine if they are appropriate for you and to discuss the appropriate dosage. It is also important to avoid taking calcium supplements at the same time as foods high in oxalic acid (such as spinach and rhubarb) or phytic acid (such as whole grains and legumes), as these substances can interfere with the absorption of calcium. Finally, it is important to maintain a healthy, balanced diet and lifestyle to support overall health and well-being and to work with a healthcare professional to address any underlying health issues or concerns.

Frequently Asked Question


  1. Satyanarayana U, Chakrapani U, Biochemistry, Chemical constituents of life, 4th edition, 2013, 116-165
  2. Kyowa Kirin Limited, Electronic medicines compendium (EMC), [ Revised on Feb 2017] [ Accessed on 8th May 2023],
  3. KD Tripathi, Essentials of Medical Pharmacology, Drugs Affecting Calcium Balance, 7th edition, 2013, 340-342


The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.