This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Carbetocin was approved by Health Canada and the United Kingdom in 1997, which belongs to the class called oxytocin receptor antagonist. It is indicated to prevent excessive bleeding in women who have recently delivered their babies.

Mechanism of Action of undefined

Carbetocin Injection functions similarly to oxytocin hormone by binding to specific uterine muscles, inducing their contraction, and reducing bleeding by stopping uterine bleeding.

Uses of undefined

Carbetocin prevents excessive bleeding in women who have recently delivered their babies. It is a synthetic, nonapeptide form of the hormone oxytocin, which promotes contractions of muscle cells in the uterus and epithelial cells in the breast. This hormone helps induce labor during delivery time and reduces blood flow from the placenta to the baby after delivery.

undefined Drug administaration and Dosage available

Carbetocin will be administered to you by a healthcare professional in a hospital setting. It is usually administered as an injection or infusion in the vein (intravenous) or muscle (intramuscular). Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.

Warnings, Precautions and Side Effects of undefined

Warnings

Carbetocin should not be administered if you are pregnant or in labor with an undelivered baby, allergic to Carbetocin or its ingredients, or allergic to oxytocin. Avoid taking this medicine if you have liver or kidney disease, serious heart disease, or epilepsy.

Precautions

Notify your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant or breastfeeding. Before taking this medicine, it is crucial to inform your physician if you have experienced migraines, have asthma, pre-eclampsia (high blood pressure in pregnancy), eclampsia (toxemia of pregnancy), heart or circulation issues (like high blood pressure), or any other medical conditions. 

Side Effects

The most common side effects of Carbetocin are low blood pressure, anemia, tiredness, loss of energy, nausea, vomiting, stomach pain, itching, fever, headache, dizziness, and shakiness. Serious side effects while taking Carbetocin are anxiety, including breathlessness, chest pain, and rapid heartbeat.

Word Of Advice

Follow the prescribed dosage and administration instructions provided by your healthcare professional. Inform your doctor about any known allergies or medical conditions you have before receiving Carbetocin. If you notice any unexpected or severe side effects, such as difficulty breathing or an allergic reaction, seek immediate medical attention. Inform your healthcare professional about any other medications or supplements you are consuming to avoid potential drug interactions. If you have any concerns regarding the treatment, consult your healthcare professional for information. 

Frequently Asked Question

References

  1. Centaur Pharma, Patient Information Leaflet, [Revised on Jan 2022] [Accessed on 28th August 2023], Carbetocin-Ferring-Patient-Information-Leaflet.pdf(d2gohj824v350l.cloudfront.net)
  2. Ferring Inc., [Revised on 21st Feb 2020] [Accessed on 21st Mar 2022], https://www.ferring.ca/media/1253/eng-duratocin-vial-pm-eng-21feb2020.pdf
  3. Roger K. Long, Hakan Cakmak, Hypothalamic & Pituitary Hormones, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 667-686.

Disclaimer

The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.