This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

The U.S. FDA approved Carboplatin as an anticancer medication to treat certain types of lung and ovarian cancer on 07th April 2003. 

Mechanism of Action of undefined

Carboplatin is used alone or with other drugs to treat ovarian cancer. This medication helps in controlling the spread of cancer.

Uses of undefined

Carboplatin acts as an alkylating agent. This medicine inhibits the synthesis of DNA, RNA, and proteins which causes programmed cell death by interrupting DNA replication. 

undefined Drug administaration and Dosage available

Carboplatin is an intravenous infusion drug that is injected through the veins. Your physician will choose the dosage and administration frequency based on your medical condition because it differs for each person.

Warnings, Precautions and Side Effects of undefined

Warnings

Consult your doctor if you are breastfeeding, pregnant, or may be pregnant before starting with Carboplatin intravenous infusion. Use effective contraception while receiving treatment with this medication and continue to use it for six months even after finishing treatment. Carboplatin may reduce fertility temporarily or permanently in both men and women. Inform your doctor, If you are taking or recently took or plan to take any other medications. Consult your doctor if you belong to older people (over 65 years old). Notify your doctor if you have already received treatment with cisplatin or other anti-cancer medications.

Precautions

Carboplatin can cause heart problems, serious irregular heartbeat, heart failure, and bone marrow depression. Inform your doctor about your medical history before starting the treatment. Notify your doctor if you have a history of hypersensitivity and kidney disease. Talk with your doctor if you have recently had a yellow fever vaccination or plan to have one. This drug may cause allergic reactions. Inform your doctor if you have kidney problems and heart-based diseases. If you have any kidney condition, ask your physician to check on you more frequently

Side Effects

The common side effects that may occur while undergoing treatment with carboplatin is loss of taste, diarrhea, constipation, hair loss, skin rashes, itchiness, kidney problem, extreme tiredness, weakness, inflammation in lung tissues, tingling or numbness in your hands, arms or legs, prickling sensation and difficulties in breathing. 

Some serious effects that are likely to occur while you are on the treatment with Carboplatin injections are a decrease in the number of red blood cells (anemia), allergic reactions, abnormal bruises, kidney problems (haemolytic-uraemic syndrome), hearing problems, and signs of infection. 

Word Of Advice

Since both men and women may experience temporary or permanent reductions in fertility while being treated with carboplatin, it is advised to discuss any fertility concerns you may have with your doctor. Carboplatin can make you feel dizzy, so avoid driving or handling machines after taking this medication. If you experience any symptoms mentioned above, consult your doctor immediately. 

Frequently Asked Question

References

  1. Hospira UK Limited, Electronic medicines compendium (EMC), [Revised on Oct 2021], [Accessed on 22nd Feb 2023],https://www.medicines.org.uk/emc/files/pil.3787.pdf
  2. Teva Parenteral Medicines, Inc, U.S Food & Drug Administration FDA, [Revised on Oct 2011,[Accessed on 22nd  Feb 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/077139Orig1s016lbl.pdf
  3. Wim J. F. van der Vijgh et.al; Clinical Pharmacokinetics of Carboplatin; [Published online on 09 Nov 2012];[Accessed on 22nd  Feb 2023]; https://link.springer.com/article/10.2165/00003088-199121040-00002 

Disclaimer

The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.