This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

The U.S. FDA-approved Cefazolin sodium to treat bacterial infections on March 18, 198. Cefazolin sodium is an antibiotic drug with an active ingredient called Cefazolin sodium. It belongs to the medication class known as Cephalosporins. 

Mechanism of Action of undefined

Cefazolin sodium works by binding to specific penicillin-binding proteins inside the bacterial cell wall and inhibiting cell wall synthesis.

Uses of undefined

Cefazolin sodium is used to treat infections in different body parts, such as skin, joints, and bones, caused by bacteria. These antibiotics work by killing the bacteria that are causing your infection. 

undefined Drug administaration and Dosage available

A healthcare professional will administer cefazolin sodium in a hospital setting. It is usually administered via different routes, including intravenous infusion (drip), slow injection into a vein, or deep injection into a large muscle. Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.

Warnings, Precautions and Side Effects of undefined

Warnings

Cefazolin sodium should not be taken if you have allergies to Cefazolin sodium, other cephalosporin antibacterial drugs, penicillins, other beta-lactam drugs, or any of the medication's ingredients. It is not recommended for premature infants or infants under one month of age. The safety of this medication in such cases has not been established. Patients with kidney disease should consume this medicine cautiously. Notify your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant or breastfeeding because it may be unsafe to use this medicine during pregnancy and breastfeeding.

Precautions

Before taking Cefazolin sodium, inform your doctor if you have a history of intestinal disorders, particularly colitis (bowel inflammation), kidney problems, or if you are following a low sodium diet. It is unknown whether consuming alcohol can cause any harmful side effects or not. Consult your doctor for more information.

Side Effects

The most common side effects of Cefazolin sodium are nausea or vomiting, diarrhea, injection site reactions (swelling, pain, redness), oral or vaginal infection, and loss of appetite. Serious side effects while taking Cefazolin sodium are abdominal or stomach cramps, fever, allergic reaction (swelling in the face, lips, or tongue, skin rash, itching, or hives), shortness of breath, unusual bleeding or bruising, and frequent infections (severe chills, mouth ulcers). 

Word Of Advice

In case of kidney problems, a lower dosage of Cefazolin Sandoz may be prescribed, and a blood test will be taken. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. Notify your doctor if you experience any serious side effects. Contact your doctor for more information. Keep out of sight and reach of pets and children. Do not freeze the medicine. Do not store above 25°C. Always check the expiry date before consuming it.`

Frequently Asked Question

References

  1. K Ries et al; Clinical and in vitro evaluation of cefazolin, a new cephalosporin antibiotic; Antimicrobial agents and Chemotherapy; Published on Feb 1973; [Accessed on 22nd June 2023]; http://www.ncbi.nlm.nih.gov/pmc/articles/pmc444382/
  2. B.Braun Medical Inc, US Food and Drug Administration, [Revised on Jan 2012] [ Accessed on 22nd June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/050779s019lbl.pdf
  3. Sandoz Pty Ltd, Package information leaflet, [Published on July 2014] [Accessed on 22nd June 2023], https://www.nps.org.au/assets/medicines/01e3720f-62ad-4cc6-8f06-a53300ff19ec-reduced.pdf
  4. Package leaflet: Information for the patient, [Accessed on 22nd June 2023], https://file.wuxuwang.com/hma/DE_H_5116_001_FinalPI_2of3.pdf

Disclaimer

The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.