This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

The US FDA Approved Cilnidipine+ Nebivolol on 17th December 2007 to treat blood pressure. This medicine belongs to the medication class known as anti-hypertensives.

Mechanism of Action of undefined

Cilnidipine acts by blocking both L- and N-type calcium channels which relaxes the blood vessels. It helps lower blood pressure, making the heart's pumping action more effective and the blood flow more smoothly. Nebivolol works by reducing heart rate and relaxing blood vessels to enhance blood circulation and reduce blood pressure. Together, they treat people with hypertension who cannot be managed with a single medication.

Uses of undefined

Cilnidipine + Nebivolol is used for controlling blood pressure when a single medication is ineffective. Hypertension (high blood pressure) is a medical condition in which blood exerts a force on the artery walls (blood vessels), resulting in heart disease, irregular heartbeat, and other problems.

undefined Drug administaration and Dosage available

Cilnidipine+ Nebivolol can be taken with food or without food. It should be swallowed whole with a glass of water. Do not chew, crush, or break it. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

Warnings, Precautions and Side Effects of undefined


Do not consume Cilnidipine + Nebivolol if you are allergic to Cilnidipine and Nebivolol or any of the ingredients in the medication. Do not take Cilnidipine+ Nebivolol if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment. Before treatment with Cilnidipine+ Nebivolol, let your physician know if you have low blood pressure (hypotension), diabetes, cardiogenic shock (sudden stopping of blood flow to the heart), hyperthyroidism (overactivity of the thyroid gland), Raynaud's disease (poor circulation in arms or legs), phaeochromocytoma and chronic bronchitis. Hence, your doctor may regularly monitor your blood pressure, electrolytes, and potassium level in your blood at regular intervals. It should not be given to children less than 12 years of age.


Additionally, disclose if you have underlying conditions such as diabetes, heart issues, lung disease, or lactose intolerance. This medicine should be used with caution in patients with severe kidney disease. Dose adjustment is required based on the kidney condition. It is advised to monitor your blood pressure regularly. It would be best to have potassium and electrolytes check-ups while taking Cilnidipine + Nebivolol to prevent complications. Do not take this medication if a patient has asthma, wheezing, or a tumor in the adrenal gland. Taking a low-salt diet and regular exercise is recommended for better results.

Side Effects

Common side are headache, constipation, cold extremities, nausea, sleepiness, tiredness, palpitations, ankle swelling, flushing, edema, dizziness, increased frequency of urination, and an unusual sensation of itching or tingling, along with potential shortness of breath.

Word Of Advice

Before initiating treatment with Cilnidipine + Nebivolol, it's crucial to inform your doctor if you have any allergies to Cilnidipine, Nebivolol, or any of the components present in the formulation.

Frequently Asked Question


  1. KD Tripathi, Essentials of Medical Pharmacology, Antiadrenergic Drugs and Drugs for Glaucoma, 7th Edition, 2013, 148-149.
  2. Torrent Pharmaceuticals, Nebicard LN. Nebivolol Hydrochloride & Cilnidipine Tablet, [Revised in February 2022] [Accessed on 18th August 2023],
  3. Forest Pharmaceuticals Inc., US Food and Drug Administration, [ Revised on December 2011] [ Accessed on 18th August 2023],


The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.