This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Cinitapride, Pantoprazole are the gastroprotectants developed by the U.S. Food And Drug Administration for treating gastroesophageal reflux disease (GERD) and non-ulcer dyspepsia.

Mechanism of Action of undefined

The first drug is a prokinetic agent that enhances gastrointestinal motility by stimulating 5-HT4 receptors and blocking dopamine D2 receptors. On the other hand, the second drug is a proton pump inhibitor that mainly reduces stomach acid production by inhibiting the ATPase enzyme system in the gastric parietal cells. Combining these two medications may completely relieve gastroesophageal reflux disease (GERD) symptoms, including improved gastric motility and reduced acid production.

Uses of undefined

Cinitapride, Pantoprazole, treats gastroesophageal reflux disease (GERD), in which the stomach acid and contents flow back into the esophagus. This capsule is also used to treat non-ulcer dyspepsia. It is a condition characterized by chronic pain or discomfort in the upper abdomen.

undefined Drug administaration and Dosage available

Take the Cinitapride and Pantoprazole as advised by your physician. Swallow the capsule whole and intact. This capsule should be taken with food. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the medicine if your doctor advises you to stop.

Warnings, Precautions and Side Effects of undefined


This drug is contraindicated in patients with tardive dyskinesia, a movement disorder condition associated with the long-term use of certain neuroleptic drugs. If a patient has a confirmed history of tardive dyskinesia related to the use of neuroleptics, this drug should be avoided. Also, hemorrhages, obstructions, or perforations are contraindications for using Cinitapride and Pantoprazole. These conditions involve structural abnormalities or severe damage to the gastrointestinal tract, and the increased gastric motility caused by this drug could worsen the situation or lead to further complications. Inform your doctor about the underlying issues, and they may provide some medical interventions to be followed.


Suppose an individual has a known history of allergic reactions or hypersensitivity to cinitapride or any of the ingredients used in the medication formulation. In that case, it should not be prescribed to them. If you suspect an allergic reaction, inform your healthcare provider before starting or continuing the medication. Cinitapride and Pantoprazole are not recommended for use during the first three months of pregnancy. If you suspect pregnancy or planning to become pregnant and have concerns about using this drug, it is highly advisable to discuss this with your healthcare provider.

Side Effects

The side effects known to occur commonly during the treatment with Cinitapride, Pantoprazole are headache, nausea, diarrhea, abdominal pain, flatulence, constipation, rash, and dizziness. Some serious side effects also include swelling of the tongue or throat, difficulty in swallowing, breathing, allergic facial swelling, severe dizziness with heavy sweating, stomach pain or cramping, fever, joint pain or muscle weakness, and unusual tiredness or fatigue.

Word Of Advice

Take Cinitapride and Pantoprazole with or after meals. Some of the gastro-protectant medications work best when taken with food. It helps to protect the stomach wall lining and reduce the risk of stomach irritation. Avoid eating spicy or acidic foods, fatty or greasy foods, alcohol, and caffeine. Adopting a healthy lifestyle can help promote better gastrointestinal health. It mainly includes maintaining a balanced diet, regular exercise, managing stress levels, getting enough sleep, and avoiding excessive use of over-the-counter pain relievers (NSAIDs) unless prescribed by a healthcare professional.

Frequently Asked Question


  1. Takeda UK Limited, Electronic Medicines Compendium (EMC), [Revised on April 2022]  (Accessed on 26 May 2023),
  2. Cinitapride, National Center for Biotechnology Information. PubChem Compound Database. Available at: (Accessed on 26 May 2023).
  3. Cinita insert folded - Available at: (Accessed: 26 May 2023).
  4. Wyeth Pharmaceuticals LLC, US Food and Drug Administration, [Revised on Nov 2020] (Accessed on 26 May 2023),,022020s018lbl.pdf
  5. Bertram.G.Katzung, Basic and Clinical Pharmacology, Drugs Used in the Treatment of Gastrointestinal Diseases, 14th edition, 2017, 1091-1095.


The drug information on this page is not a substitute for medical advice; it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.