This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Cyclophosphamide is a chemotherapy medication developed by the U.S. Food And Drug Administration for treating various malignancies (abnormal production of cells is called cancer and if they spread to other organs then they are called malignancies).
Mechanism of Action of undefined
Cyclophosphamide slows or stops the growth of cancer cells by damaging the hereditary material (DNA and RNA) of the cancer cells. In nephrotic syndrome, it works by suppressing the body’s immune system.
Uses of undefined
Cyclophosphamide helps to treat various malignancies (abnormal production of cells is called cancer and if they spread to other organs then they are called malignancies). Cyclophosphamide can be used to treat malignant lymphomas (cancers that start from the lymphatic system of the body- vessels, fluid, and lymphoid tissue) such as Hodgkin’s disease, lymphocytic lymphoma, and mixed-cell type lymphoma.
undefined Drug administaration and Dosage available
Cyclophosphamide is available in the form of a tablet and injections. The recommended Cyclophosphamide dose for tablets is 50mg and injection is 1gm, 200mg, 500mg, 1000mg . Depending on your age, weight, and disease condition, your doctor will determine your appropriate dose and duration. Do not stop using this medicine unless your doctor instructs you.
Warnings, Precautions and Side Effects of undefined
Inform your doctor immediately if you experience allergies to Cyclophosphamide and its ingredients. Cyclophosphamide is contraindicated in pregnancy, patients with acute infections, urinary tract infections, urinary outflow obstruction, and bone marrow disorders.
Treatment with this medicine may lead to immune suppression, bone marrow failure, cardiotoxicity, renal toxicity, pulmonary toxicity, and secondary malignancies. Inform your doctor if you have pre-existing kidney disease, immune conditions, cardiac disorders, or liver diseases.
The side effects known to occur commonly during the treatment with Cyclophosphamide are nausea, vomiting, low white blood cell count, diarrhea, hair loss, fever, weakness, inflammation , dizziness, blurred vision, and amenorrhea.
Word Of Advice
Inform the doctor if the patient has any kidney, liver, heart problems and medication taken for different medical conditions. It causes immune suppression and hence inform the doctor if there are any immunity related problems. This medication should be avoided in pregnant women and breast feeding mothers. The patient undergoing treatment with this medicine may have dizziness, blurred vision. Consult your doctor before driving and handling heavy machines.
Frequently Asked Question
- Baxter, Electronic medicines compendium (emc), [ Revised on June 2016] [ Accessed on 8th April 2021], https://www.medicines.org.uk/emc/product/1815/smpc
- Baxter, US Food and Drug Administration, [ Revised on May 2013] [ Accessed on 7th April 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/012141s090,012142s112lbl.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 860.
The drug information on this page is not a substitute for medical advice; it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.