This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Cranberry extract+D-mannose contains an active component as Cranberry extract+D-mannose. These natural substances can be used as an alternative or complement to antibiotic treatment for urinary tract infections (UTIs). Cranberry extract is derived from cranberry fruit and is known for its potential benefits in preventing UTIs. It contains compounds called proanthocyanidins, which may help prevent bacteria, such as E. coli, from adhering to the walls of the urinary tract. This action can reduce the risk of UTIs. D-Mannose is a naturally occurring sugar that is similar in structure to glucose. 

Mechanism of Action of undefined

The combined therapeutic effect of Cranberry extract+D-mannose supplements aims to support urinary tract health by potentially preventing the adherence of bacteria to the urinary tract walls and aiding in the flushing out of any attached bacteria. Cranberry extract's proanthocyanidins may inhibit bacterial adhesion, while D-mannose can attach to bacteria, particularly E. coli, and facilitate their removal through urine. This dual action may reduce the risk of urinary tract infections and alleviate associated symptoms.

Uses of undefined

Cranberry extract+D-mannose used to reat and prevent urinary tract infections

undefined Drug administaration and Dosage available

When using Cranberry extract+D-mannose, following the instructions provided by your healthcare professional or the product packaging is important. Typically, it is taken orally with or without food. The dosage and frequency of use will depend on the specific medical condition being treated and individual needs.

Warnings, Precautions and Side Effects of undefined

Warnings

Before using cranberry extract+D-mannose supplements, it is important to be aware of certain precautions. These supplements may cause allergies or sensitivities, so discontinue use and seek medical attention if allergic reactions occur. Individuals with diabetes should closely monitor their blood sugar levels as D-mannose can affect glucose levels and may require adjustments to medication or insulin under medical supervision. There may be potential drug interactions, especially with blood thinners. 

Precautions

Seek immediate medical attention if you experience rash, itching, swelling, dizziness, or difficulty breathing. It is crucial to be aware of associated warnings and closely follow healthcare provider instructions. Use caution if you have a history of kidney stones due to the moderate oxalate content in cranberry extract. Discontinue use if gastrointestinal symptoms persist. If you are pregnant, breastfeeding, have underlying medical conditions, or are taking medications, it is advisable to consult with a healthcare professional before using these supplements.

Side Effects

Cranberry extract+D-mannose is generally well-tolerated, but it can potentially cause side effects in some individuals. Common side effects may include gastrointestinal upset like nausea, bloating, or gas. Allergic reactions, although rare, can manifest as rash, itching, swelling, dizziness, or difficulty breathing.

Word Of Advice

When using Cranberry extract+D-mannose supplements, always follow the recommended dosage instructions provided by the manufacturer. Taking excessive amounts may lead to unwanted side effects or interactions. Additionally, suppose you have any underlying medical conditions, such as diabetes, kidney problems, or liver disease, or are pregnant or breastfeeding. In that case, it is crucial to consult with a healthcare professional before starting these supplements to ensure their safety and appropriateness for your specific situation. Regular health monitoring may be recommended, including blood sugar levels or kidney function. Avoid using in children. Remember that supplements should not replace professional medical care, and it is always best to seek guidance from a qualified healthcare professional to ensure the safe and appropriate use of these supplements.

Frequently Asked Question

References

  1. Satyanarayana U, Chakrapani U, Biochemistry, Mineral metabolism, 4th edition, 2013.
  2. Radulescu D; Combination of Cranberry extract and D-mannose  - possible enhancer of uropathogenic sensitivity to antibiotics in acute therapy of urinary tract infections: Results of a pilot study; Experimental and Therapeutic Medicine 2020; [Accessed 20th June 2023] https://www.ncbi.nlm.nih.gov/pubmed/32905041
  3. Zhuxuan Fu et al.; Cranberry Reduces the Risk of Urinary Tract Infection Recurrence in Otherwise Healthy Women: A Systematic Review and Meta-Analysis; The Journal of Nutrition 2017; [Accessed 20th June 2023]; https://pubmed.ncbi.nlm.nih.gov/29046404/

Disclaimer

The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.