Dalteparin received its initial approval from the U.S. Food and Drug Administration (FDA) on December 31, 1993. It was first marketed under Fragmin, and subsequent generic versions have also been approved.

Dalteparin Injection has been developed to treat venous thromboembolism and its symptoms in adults and pediatric patients older than one month of age. It also prevents the occurrence of deep vein thrombosis in abdominal surgery, hip replacement surgery, knee replacement surgery and in people with severe movement restriction. In patients with unstable angina and non-Q wave myocardial infarction, Dalteparin prevents further heart complications.

A healthcare professional will administer Dalteparin injection to the patients through subcutaneous route. Dalteparin is available as multidose solution for injection in the doses 2500IU, 5000IU and 10000IU. The accurate dose will be calculated according to the age, body weight and medical condition.

The common side effects that are likely to occur while you are on the treatment with Dalteparin Injection are bleeding, anaemia, thrombocytopenia, abnormal values of liver enzymes and pain at the injection site. If you experience any allergic reactions after taking this injection, report to your doctor immediately.

Dalteparin injection is not recommended for patients with active bleeding, hypersensitivity and history of heparin-induced thrombocytopenia. Tell your physician before taking this injection if you are allergic to Dalteparin sodium, heparin, benzyl alcohol or rubber. Your healthcare provider will regularly monitor your blood count. Inform your healthcare practitioner if you are diagnosed with liver or kidney problem.

Tell your healthcare provider if you are pregnant, breastfeeding or planning to have a baby. Dalteparin injection is probably unsafe during pregnancy as it may increase the risk of thrombosis in pregnant women and is harmful for pregnant women and their foetus.

Dalteparin can cause bleeding and many undesirable side effects; hence it is advised to get adequate rest during the treatment. Eat a well-balanced diet. If you experience dizziness or any visual disturbances, you should avoid driving or handling machines. Apply cool compress at the injection site to reduce pain and irritation.

1. Pfizer, [Revised on Jun 2020] [Accessed on 27th Sep 2022], https://labeling.pfizer.com/ShowLabeling.aspx?id=2293

2. KD Tripathi, Drugs Affecting Coagulation, Bleeding and Thrombosis, Essentials of Medical Pharmacology, 8th Edition, 2019, 659-681.

The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.