This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Dapoxetine belongs to the pharmacological class of selective serotonin reuptake inhibitors (SSRIs).
Mechanism of Action of undefined
Dapoxetine's mechanism of action involves inhibiting serotonin reuptake in the brain, leading to increased serotonin levels in the synaptic clefts. This alteration in serotonin levels helps delay ejaculation by improving ejaculatory control and extending the time it takes for ejaculation to occur. As a result, it effectively treats premature ejaculation, providing men with enhanced sexual experiences and satisfaction.
Uses of undefined
Dapoxetine is used primarily for the treatment of premature ejaculation in adult men. As a selective serotonin reuptake inhibitor (SSRI), it helps increase serotonin levels in the brain, which in turn delays ejaculation and improves ejaculatory control. It is typically prescribed as an on-demand treatment, taken one to three hours before anticipated sexual activity. The main and approved use of this medication is for managing premature ejaculation, allowing men to have more satisfying and prolonged sexual experiences.
undefined Drug administaration and Dosage available
Dapoxetine is typically administered orally in the form of tablets or capsules. The medication is taken by mouth with water and is commonly used as an on-demand treatment for premature ejaculation. It is essential to follow the guidance provided by a healthcare professional for safe and effective use.
Warnings, Precautions and Side Effects of undefined
Dapoxetine has been associated with an increased risk of suicidal thoughts, especially in individuals under 25. This medication may increase serotonin levels, and in combination with other medications affecting serotonin (such as antidepressants), it may lead to serotonin syndrome, a potentially life-threatening condition. It may cause a drop in blood pressure, leading to orthostatic hypotension, especially when changing positions (e.g., from lying down to standing up). It may lower the seizure threshold in some cases.It has been associated with a slight increase in bleeding time.
Close monitoring for changes in mood, behavior, or suicidal ideation is crucial during treatment with this medication. Avoid concurrent use of this medication with other serotonergic drugs. Take precautions to prevent falls and dizziness. Stay adequately hydrated while using it, especially if experiencing diarrhea or vomiting, to avoid dehydration. Do not exceed the recommended dosage of this medication to avoid an increased risk of side effects or potential overdose.
Common side effects of Dapoxetine may include nausea, headache, dizziness, diarrhea, fatigue, and dry mouth. These side effects are usually mild and temporary; most individuals tolerate the medication well. However, there are more serious or less common side effects that may require immediate medical attention, such as allergic reactions (e.g., skin rash, itching, swelling), fainting or loss of consciousness, severe dizziness or lightheadedness, changes in mood or behavior (e.g., agitation, anxiety), and vision changes or blurred vision.
Word Of Advice
Consult a healthcare professional before starting the medication to ensure its suitability. Inform your healthcare provider about any history of allergic reactions or medication hypersensitivity. Do not exceed the recommended dosage of Dapoxetine to avoid an increased risk of side effects or potential overdose. Be cautious if you have low blood pressure or a tendency to faint, as it may cause a decrease in blood pressure or dizziness. If you experience symptoms of dehydration, such as diarrhea or vomiting, ensure proper hydration. Avoid sudden changes in posture to prevent orthostatic hypotension. Discuss any history of bleeding disorders or use of blood-thinning medications, as it has been associated with a slight increase in bleeding time. Follow your healthcare provider's advice regarding the appropriate duration of treatment, as it is typically used as an on-demand medication for premature ejaculation.
Frequently Asked Question
- KD Tripathi, Essentials of Medical Pharmacology, Antidepressant and antianxiety drugs, 7th edition, 2013, 461 - 462.
- A. Menarini Farmaceutica Internazionale SRL, Electronic medicines compendium (EMC), [Revised on 28 Sep 2021] [Accessed on 3rd August 2023], Priligy 30 mg film-coated tablets - Summary of Product Characteristics (SmPC)
- Chris G McMahon; Dapoxetine: a new option in the medical management of premature ejaculation; Therapeutic Advances in Urology; Published on Oct 2012; Accessed on 29/06/2021; https://www.ncbi.nlm.nih.gov/pubmed/23024705
The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.