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Written By
P. Thirumal Reddy
B. Pharm

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:31 AM (IST)

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Quick Summary
DARIFENACIN
Last updated on 31 Mar 2026 | 09:31 AM (IST)
DARIFENACIN
Background and Date of approval DARIFENACIN
Darifenacin is a urinary antispasmodic drug developed by the U.S. Food And Drug Administration and initially approved for treating the symptoms of overactive bladder (OAB).
Uses of DARIFENACIN
Darifenacin is used to treat the symptoms of overactive bladder (OAB). It is a medical condition caused by a sudden, frequent, and uncontrollable urge to urinate, often accompanied by urinary frequency (urinating more often than usual) and urinary urgency (a strong and immediate need to urinate). Individuals with OAB may experience these symptoms even when the bladder is not full, leading to a sense of urgency that can be difficult to control.
How is DARIFENACIN administered?
Take the Darifenacin as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the capsule if your doctor advises you to stop.
Side Effects of DARIFENACIN
The side effects known to occur commonly during the treatment with Darifenacin are headache, stomach pain, indigestion, sickness, dry eyes, nasal dryness, dry mouth, constipation, urinary tract infection, nausea, flu-like illness, and accidental injury.
Warnings
This drug is contraindicated in individuals with known hypersensitivity or allergy to it or its component. Individuals with certain medical conditions, such as ulcerative colitis, myasthenia gravis, narrow-angle glaucoma, severe liver disease, or urinary retention, should avoid consuming Darifenacin..
Precautions
It's important to provide your doctor with a complete medical history to determine if the medication is suitable for you. Also, this drug is not recommended during pregnancy and should be taken cautiously while breastfeeding. Grapefruit juice may interact with this medicine and affect its absorption. It's recommended to avoid grapefruit juice while taking this medication.
Word of Advice
Darifenacin can cause dizziness or blurred vision in some individuals. If you experience these effects, avoid activities that require mental alertness or clear vision until you know how the medication affects you.
Frequently Asked Questions
Q1.
Is it ok if I drink grapefruit juice while taking Darifenacin?
Grapefruit juice may interact with Darifenacin and affect its absorption. It's recommended to avoid grapefruit juice while taking this medication.
Q2.
Who can benefit from taking Darifenacin?
Darifenacin is beneficial for individuals who experience symptoms of overactive bladder, such as a sudden urge to urinate, frequent urination, and involuntary leakage of urine.
Q3.
Can Darifenacin cure overactive bladder?
Darifenacin does not cure overactive bladder, but it can effectively manage the symptoms. It's important to continue taking the medication as prescribed to maintain symptom relief.
Q4.
Who should not take Darifenacin?
Darifenacin should be avoided by individuals with certain medical conditions, including urinary retention, gastric retention, uncontrolled narrow-angle glaucoma, severe liver impairment, or known hypersensitivity to the medication.
Q5.
Can I take other medications with Darifenacin?
Inform your doctor about all medications, supplements, and herbal products you're taking, as some drugs may interact with Darifenacin and affect its effectiveness or increase the risk of side effects.
References
- Merus Labs Luxco II S.à R.L, Electronic Medicines Compendium (EMC), [Revised on Nov 2020] [Accessed on 25th August 2023], https://www.medicines.org.uk/emc/files/pil.5129.pdf
- Novartis Pharma Stein AG, US Food & Drug Administration, [Revised on Mar 2012] [Accessed on 25th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021513s010lbl.pdf
- KD Tripathi, Anticholinergic Drugs and Drugs Acting on Autonomic Ganglia, Essentials of Medical Pharmacology, 8th Edition, 2019,.124-135.
- J. Goddard, A.N. Turner, Kidney and urinary tract disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 461-523.
Disclaimer
The drug information on this page is not a substitute for medical advice; it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.






