Dexlansoprazole is an antiulcer drug developed by the U.S. Food And Drug Administration and initially approved in 1995 for treating Gastroesophageal Reflux Disease (GERD).

Dexlansoprazole is to treat conditions such as gastroesophageal reflux disease (in which the stomach acid and contents flow back into the esophagus, leading to symptoms like heartburn, regurgitation, and difficulty swallowing), peptic ulcers, and other acid-related disorders.

Take the Dexlansoprazole as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

The side effects known to occur commonly during the treatment with Dexlansoprazole are allergic reactions, severe diarrhea, and abdominal discomfort. Some serious side effects include stomach pain, common cold, nausea, vomiting, and flatulence.

Contact your physician immediately if you experience allergies to this drug and its ingredients. Individuals with severe liver problems may have impaired liver function, which can affect the metabolism and elimination of Dexlansoprazole. In such cases, the use of this drug may need to be adjusted, or alternative treatment options may be considered. Inform your physician if you have stomach problems, as your doctor may need to adjust your dosage accordingly during these conditions. Do not administer this drug to children or adults under 18 years old.

Long-term use of this medicine may result in low magnesium levels in the body (hypomagnesemia). Symptoms of low magnesium levels include fatigue, muscle spasms or weakness, irregular heartbeat, and seizures. If you develop any of these symptoms, notify your doctor immediately. It is necessary to discuss using Dexlansoprazole with your physician if you are pregnant, suspecting pregnancy, or breastfeeding.

Dexlansoprazole is usually taken at least one hour before meals. Follow the general instructions given by your doctor regarding the timing and dosing of the medication. While taking this medicine, making certain dietary modifications to support your treatment may be helpful. Avoid foods and beverages that trigger your symptoms, such as spicy or acidic foods, caffeine, and alcohol. Eat smaller meals and avoid eating close to bedtime. Consider elevating the head of your bed to help reduce nighttime acid reflux.

1. Takeda Pharmaceuticals America Inc, US Food and Drug Administration, [ Revised on Jan 2016] [ Accessed on 5th Sep 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/208056lbl.pdf
2. Takeda Pharma A/S, The Health Products Regulatory Authority (HPRA), [ Revised on Jan 2015] [Accessed on 5th Sep 2023], http://www.hpra.ie/img/uploaded/swedocuments/PIL-2159149-15072015133904-635725643461415000.pdf
3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Pharmacotherapy of acidity, ulcers, and reflux disease, 12th edition, 2011, 1311.

The drug information on this page is not a substitute for medical advice; it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.