This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Diphtheria tetanus, Haemophil, Hepatitis B, Pertussis, Poliomyelitis was approved by the U.S. FDA to protect your child against Diphtheria tetanus, Haemophil, Hepatitis B, Pertussis, and Poliomyelitis.
Mechanism of Action of undefined
Diphtheria tetanus, Haemophil, Hepatitis B, Pertussis, Poliomyelitis stimulates the immune system to produce antibodies against the specific microorganisms that cause the targeted diseases. It helps the body to recognize and fight off these infections if exposed to them in the future.
Uses of undefined
Diphtheria tetanus, Haemophil, Hepatitis B, Pertussis, Poliomyelitis is used to protect your child against Diphtheria tetanus, Haemophil, Hepatitis B, Pertussis, and Poliomyelitis. Diphtheria is a serious bacterial infection that mainly affects the airways and sometimes the skin. The airways become swollen, causing serious breathing problems and sometimes suffocation. Tetanus, also known as lockjaw, is a bacterial infection caused by Clostridium tetani. It can cause muscle stiffness and spasms. Haemophil (Hib) is a bacterium that can cause severe infections, including pneumonia, meningitis, and throat infections, especially in young children. Hepatitis B is a viral infection that affects the liver. It can lead to chronic liver disease and increase the risk of liver cancer. Pertussis, also known as whooping cough, is a highly contagious respiratory infection caused by Bordetella pertussis. Poliomyelitis, commonly known as polio, is a viral infection that can cause paralysis and muscle weakness.
undefined Drug administaration and Dosage available
The Diphtheria tetanus, Haemophil, Hepatitis B, Pertussis, Poliomyelitis is administered as an injection, given in the upper thigh (for infants and young children) or the upper arm (for older children). The primary schedule consists of three doses given at 2, 4, and 6 months of age, followed by booster doses in the second year of life.
Warnings, Precautions and Side Effects of undefined
This Diphtheria tetanus, Haemophil, Hepatitis B, Pertussis, Poliomyelitis is not recommended if your child has a bleeding disorder or is receiving anticoagulant therapy. Special precautions may be necessary to minimize the risk of bleeding at the injection site. It is important to inform the healthcare professional about any bleeding disorders or medications your child takes. The immune response to the vaccine can be reduced if your child has a weakened immune system due to a medical condition or medication. The vaccine's effectiveness may be lower in these cases, and the healthcare professional should evaluate the risks and benefits of administering the vaccine. If your child has a history of seizures or a family history of febrile seizures, it is important to discuss this with the healthcare professional. While the vaccine does not generally cause seizures, febrile seizures can occur after vaccination due to fever. The healthcare professional can provide appropriate guidance and recommendations. If your child experienced significant adverse events following previous vaccinations, such as high fever or severe allergic reactions, it is important to inform the healthcare professional immediately. They can assess the situation and determine if any precautions or additional monitoring are necessary.
It should not be administered if your child is allergic to this vaccine or its ingredients. Allergic reactions may manifest as itchy skin, rash, shortness of breath, or swelling of the face or tongue. If your child has experienced nervous system problems within seven days following a previous vaccination against whooping cough, this vaccine should not be administered. Most importantly, Diphtheria tetanus, Haemophil, Hepatitis B, Pertussis, Poliomyelitis should not be given if your child has a severe infection with a temperature over 38°C. Minor infections, such as a cold, may not pose a problem, but it is advisable to consult with a doctor first. If your child has a fever, it is advisable to consult with a healthcare professional before administering the vaccine. They can assess whether the vaccination should be delayed until the fever resolves or determine if it is safe to proceed.
The common side effects that are likely to occur while you are on the treatment with Diphtheria tetanus, Haemophil, Hepatitis B, Pertussis, Poliomyelitis are nausea, vomiting, headache, hair loss, weakness, fever, chills, difficulty breathing, diarrhea, inflammation diarrhoea, vomiting, loss of appetite, feeling irritable or restless, swelling at the injection site, and nervousness. Serious side effects also include severe allergic reactions like rashes that may be itchy or blistering, swelling of the eyes and face, difficulty in breathing or swallowing, and a sudden drop in blood pressure and loss of consciousness.
Word Of Advice
It is necessary to complete the recommended schedule of doses as advised by healthcare professionals to ensure your child receives the necessary protection. Always consult a healthcare professional, such as a doctor or pediatrician, for specific advice regarding vaccination and any concerns or questions you may have. Like any vaccine, Diphtheria tetanus, Haemophil, Hepatitis B, Pertussis, Poliomyelitis may cause side effects, although usually mild and temporary. Monitor your child for reactions, such as pain or swelling at the injection site, fever, or irritability. If you have any doubts, reach out to your doctor immediately.
Frequently Asked Question
- GlaxoSmithKline UK Limited, Electronic Medicines Compendium (EMC), [Revised on Jan 2021] [Accessed on 18th May 2023], https://www.medicines.org.uk/emc/files/pil.2586.pdf
- S. K. Lalwani et al., Immunogenicity and safety of 3-dose primary vaccination with combined DTPa-HBV-IPV/Hib in Indian infants, Human Vaccines & Immunotherapeutics, 2017, 13(1), 120–127,https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287296/pdf/khvi-13-01-1225639.pdf
- GlaxoSmithKline Biologicals- Infanrix Hexa . Available at: https://gskpro.com/content/dam/global/hcpportal/en_US/Prescribing_Information/Infanrix/pdf/INFANRIX.PDF (Accessed on 18th May 2023).
The drug information on this page is not a substitute for medical advice; it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.