This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

The domperidone + esomeprazole is approved for medical use for treating gastroesophageal reflux disease (Acid reflux) and functional dyspepsia.

Mechanism of Action of undefined

Domperidone is a prokinetic (to promote movement) that acts on the upper gastrointestinal tract, increasing stomach and intestines movement and allowing the food to move easily through the stomach. Esomeprazole is a proton pump inhibitor (PPI) that acts by reducing stomach acid and helps in relieving acidity and heartburn.

Uses of undefined

Domperidone + esomeprazole is used  to treat gastroesophageal reflux disease (acid reflux) and relieving indigestion symptoms (heartburn, stomach pain, or irritation). It also neutralizes the stomach acid and promotes easy gas passage to reduce stomach discomfort).

undefined Drug administaration and Dosage available

Domperidone + esomeprazole is available as a 2.5mg tablet which is administered orally.Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

Warnings, Precautions and Side Effects of undefined


Inform your doctor if you are allergic to domperidone, esomeprazole, or any of the ingredients present in them. Consult your doctor if you have liver, kidney, heart, or bone disorders. The safety and effectiveness of the drug in children has yet to be established. So, you should consult your doctor before using the drug in children.


Domperidone + esomeprazole may cause sleepiness and dizziness. It is advised to speak with your doctor before starting driving or handling heavy machines. Consult your doctor if you are planning to get pregnant or think you may be pregnant while breastfeeding.

Side Effects

The common side effects experienced while you are on the treatment with domperidone + esomeprazole are diarrhea, flatulence, stomach pain, dryness in mouth, headache.

Word Of Advice

It is recommended to inform your doctor if you are going to get a cancer diagnosis (neuroendocrine tumor diagnosis). The drug may interfere with the result, so it is advised to ask your doctor before you go to the diagnosis. It is advised to limit or avoid the consumption of cold milk and hot tea, coffee, spicy food, or chocolate to get better results with the medicine.

Frequently Asked Question


  1. Taj Pharmaceutical Limited., Manufacturer, [ Accessed on 21st Oct 2023], Esomeprazole 40mg (EC) & Domperidone 30mg SR Capsules (ESOTAJ-DSR) - Taj Pharma India.
  2. SA Quratulain et at., Effectiveness, Safety, and Tolerability of Esomeprazole and Domperidone in Gastroesophageal Reflux Disease., [published on 16th Aug 202][ Accessed on 21st Oct 2023]
  3. KD Tripathi, Essentials of Medical Pharmacology, Drugs acting on central nervous system, 2019, 701-706, 411, 714-715.


The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.