This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Domperidone, Rabeprazole is a combination of antiulcer medications developed by the U.S. Food And Drug Administration for treating gastroesophageal reflux disease, peptic ulcer and it also helps to treat nausea and vomiting.

Mechanism of Action of undefined

Rabeprazole works by irreversibly binding to the proton pump and inhibiting its function. By doing so, it blocks the final step of acid production. Specifically, this drug inhibits the enzyme's ability to transport hydrogen ions (protons) into the stomach, thereby reducing gastric acid secretion. Domperidone enhances the movement and contractions of the stomach and intestines. It helps to improve gastrointestinal motility and facilitates the food to pass through the digestive part.

Uses of undefined

Domperidone, Rabeprazole helps to treats conditions such as gastroesophageal reflux disease (in which the stomach acid and contents flow back into the esophagus), peptic ulcers (a sore or erosion that forms on the stomach lining), and nausea and vomiting.

undefined Drug administaration and Dosage available

Take the Domperidone and Rabeprazole Tablet as your physician advises. Usually, the tablets will be taken with a glass of water. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

Warnings, Precautions and Side Effects of undefined


This medicine is contraindicated in people with a history of cardiac arrhythmias such as ventricular fibrillation, ventricular tachycardia, or QT prolongation or in those taking medications that prolong the QT interval. This tablet may cause side effects such as dizziness, drowsiness, or vision changes in some individuals. If these effects occur, avoiding activities requiring alertness, such as driving, cycling, or operating machinery, is important until you feel better.


Long-term use of this medicine may result in low magnesium levels in the body (hypomagnesemia). Symptoms of low magnesium levels include fatigue, muscle spasms or weakness, irregular heartbeat, and seizures. If you develop any of these symptoms, notify your doctor immediately. It is necessary to discuss using Domperidone and Rabeprazole with your physician if you are pregnant, suspecting pregnancy, or breastfeeding.

Side Effects

The side effects known to occur commonly during the treatment with Domperidone, Rabeprazole are headache, stomach pain, diarrhea, dryness in the mouth, weakness, nausea, vomiting, infection, rash, itching, painful or tender breasts and back pain.

Word Of Advice

Take the Domperidone and Rabeprazole tablets, exactly as your physician prescribes. Do not change the dose or stop taking the medication without consulting your doctor first. This drug is usually taken at least one hour before meals. Follow the general instructions given by your doctor regarding the timing and dosing of the medication. While taking this medicine, making certain dietary modifications to support your treatment may be helpful. Avoid foods and beverages that trigger your symptoms, such as spicy or acidic foods, caffeine, and alcohol. Eat smaller meals and avoid eating close to bedtime. Consider elevating the head of your bed to help reduce nighttime acid reflux.

Frequently Asked Question


  1. Rabicip D Capsules; Ciplamed; Accessed on 02/06/2023;
  2. Savita Shahani, Prabha Sawant, Pareen Dabholkar; Rabeprazole plus Domperidone: the answer for gastro-oesophageal reflux disease; Journal of the Indian Medical Association; Published on April 2008; Accessed on 02/06/2023;
  3. Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Pharmacotherapy of acidity, ulcer, and reflux disease, 12th edition, 2011, 1319.


The drug information on this page is not a substitute for medical advice; it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.