This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Emtricitabine, Tenofovir disoproxil fumarate contain two active substances, Emtricitabine and Tenofovir disoproxil fumarate. These medications are a part of the standard combination therapy for HIV, known as antiretroviral therapy (ART). It is a combination drug regimen that is commonly used for the effective treatment of HIV-1 infection. When used correctly and consistently, Emtricitabine and Tenofovir disoproxil fumarate have demonstrated high efficacy in HIV treatment and prevention. It is a combination medication for treating and preventing HIV infection that received FDA approval on July 12, 2012.

Mechanism of Action of undefined

Emtricitabine and Tenofovir disoproxil fumarate work by inhibiting HIV replication, reducing viral load, improving immune function, and slowing the progression of HIV disease. In individuals with HIV, these medications help control the virus, maintain a low viral load, and improve overall health outcomes.

Uses of undefined

Emtricitabine and Tenofovir disoproxil fumarate is used to treat HIV -1 Infection.

undefined Drug administaration and Dosage available

To properly consume Emtricitabine and Tenofovir disoproxil fumarate, follow your healthcare provider's instructions regarding dosage, frequency, and duration. Take it with or without food, swallowing the tablets or capsules with water. Adhere to the prescribed dosing schedule; do not alter the dosage without consulting your healthcare provider.

Warnings, Precautions and Side Effects of undefined


Emtricitabine and Tenofovir disoproxil fumarate carry important warnings that should be considered. These include the risk of severe liver problems, potential kidney impairment, bone loss, lactic acidosis, immune reconstitution syndrome, drug interactions, exacerbation of infection, immune system effects, and the need for caution in patients with pre-existing conditions.


Precautions while taking Emtricitabine and Tenofovir disoproxil fumarate include regularly monitoring liver function. Close monitoring of kidney function is also recommended. Individuals with existing heart conditions or taking medications should exercise caution. Blood sugar levels may need to be monitored.

Side Effects

Common side effects of emtricitabine and tenofovir disoproxil fumarate may include nausea, diarrhea, headache, fatigue, dizziness, and insomnia. These side effects are usually mild and transient. Serious but rare side effects may include severe hypersensitivity reactions, lactic acidosis (characterized by rapid breathing, muscle pain, and stomach discomfort), liver and kidney problems, and bone loss.

Word Of Advice

If you are considering of taking Emtricitabine and Tenofovir disoproxil fumarate, it is important to be aware of the potential risks and warnings associated with this medication. Pregnancy and breastfeeding require individual evaluation and consultation with a healthcare provider to weigh the benefits against potential risks. It should be used cautiously in individuals with pre-existing conditions such as liver disease, kidney disease, or bone disorders, as it may exacerbate them. Close monitoring and appropriate management are necessary in these cases. Adherence to these precautions and regular monitoring and communication with the healthcare provider can help ensure safe and effective use.

Frequently Asked Question


  1. KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
  2. Tillomed Laboratories Limited, Electronic Medicines Compendium (EMC), [Revised on Apr 2020] [Accessed on 19th May 2023],
  3. Gilead Sciences, Inc, US Food and Drug Administration, [ Revised on March 2016] [ Accessed on 19th May 2023],


The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.