This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Enoxaparin is an anticoagulant medication which was approved for its medical use on 31st December 1998.
Mechanism of Action of undefined
Enoxaparin Injection has been developed to treat deep vein thrombosis with or without pulmonary embolism. It also prevents the occurrence of deep vein thrombosis in abdominal surgery, hip replacement surgery, knee replacement surgery and in people with severe movement restriction. In patients with unstable angina and non-Q wave myocardial infarction, Enoxaparin prevents further heart complications.
Uses of undefined
Enoxaparin Injection is an anticoagulant medication belonging to the class of low molecular weight heparin. Enoxaparin injection binds to the antithrombin to form a complex. antithrombin is a protein that blocks the formation of abnormal blood clots. Enoxaparin prevents the activation of factor Xa, eventually preventing clot formation.
undefined Drug administaration and Dosage available
A healthcare professional will administer Enoxaparin injection to the patients into their veins. Enoxaparin is available as single dose prefilled syringes in the doses 100 mg per ml and 150 mg per ml. the hundred mg per ml dose is available in the concentrations of 30 MG per 0.3 ml, 40 MG per 0.4 ml, 60mg/0.6ml, 80mg/0.8ml, 100mg/1ml, 300mg/3ml. 150mg/ml dose is available in the concentrations of 120mg/0.8ml and 150mg/1ml.
Warnings, Precautions and Side Effects of undefined
Enoxaparin injection is not recommended for patients with active bleeding, hypersensitivity and history of heparin-induced thrombocytopenia. tell your physician before taking this injection if you are allergic to Enoxaparin sodium, heparin, Benzyl alcohol or pork products. Your health care provider will regularly monitor you for signs of bleeding. inform your Healthcare practitioner if you are diagnosed with kidney problem.
Tell your healthcare provider if you are pregnant, breastfeeding or planning to have a baby. Enoxaparin injection is probably unsafe during pregnancy as it may increase the risk of thrombosis in pregnant women and is harmful for pregnant women and their fetuses.
The common side effects that are likely to occur while you are on the treatment with Enoxaparin Injection are bleeding, anaemia, thrombocytopenia, diarrhoea, nausea, fever, edema, breathlessness, confusion and pain at the injection site. If you experience any allergic reactions such as excessive sweating, chest pain, swelling of face, hands, throat or tongue after taking this injection, report to your doctor immediately.
Word Of Advice
Enoxaparin can cause bleeding and many undesirable side effects; hence it is advised to get adequate rest during the treatment. Eat a well-balanced diet. If you experience dizziness or any visual disturbances, you should avoid driving or handling machines. Apply cool compress at the injection site to reduce pain and irritation.
Frequently Asked Question
- Rovi Biotech Limited, European Medicine Consortium (EMC), [Revised on Nov 2018], Available at: https://www.medicines.org.uk/emc/files/pil.9330.pdf [Accessed on 27th May 2023].
- Sanofi, [Revised on Apr 2022] [Accessed on 27th May 2023], https://products.sanofi.us/lovenox/lovenox.pdf
- Clexane® syringes 100MG/ML solution for Injection - HPRA. [Revised on May 2022], Available at: https://www.hpra.ie/img/uploaded/swedocuments/7900ad74-3eb7-41a2-be4c-3b757cb841ec.pdf [Accessed on 27th May 2023].
- KD Tripathi, Drugs Affecting Coagulation, Bleeding and Thrombosis, Essentials of Medical Pharmacology, 8th Edition, 2019, 659-681.
The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.