This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Eptifibatide  was initially approved by the United States Food and Drug Administration (FDA) on May 17, 1998.

Mechanism of Action of undefined

Eptifibatide acts by binding to platelet glycoprotein IIb/IIIa receptors, obstructing the attachment of fibrinogen and von Willebrand factor. This interference prevents the cross-linking of platelets, slowing down the formation of stable blood clots. This mechanism is essential in situations such as acute coronary syndrome and coronary procedures where controlling clot formation is critical.

Uses of undefined

Eptifibatide is a medication primarily used to prevent blood clot formation in various medical situations. It is particularly used in cases where there is an increased risk of clotting, such as during certain cardiac procedures, acute coronary syndrome (ACS), and specific surgical interventions. It is also used for patients experiencing ACS, which includes conditions like unstable angina and non-ST segment elevation myocardial infarction (NSTEMI).

undefined Drug administaration and Dosage available

Eptifibatide is administered through intravenous (IV) infusion, which involves delivering the medication directly into the bloodstream through a vein using an IV line. This is typically done using specialized medical equipment, such as an IV pump, to control the rate of infusion. During the infusion, the patient's vital signs and overall response to the medication require close monitoring by the health care professional.

Warnings, Precautions and Side Effects of undefined


Due to effect of  Eptifibatide on platelets, it increases the risk of bleeding. Although rare, serious allergic reactions can occur. These might involve symptoms like rash, itching, swelling (especially of the face, lips, or throat), severe dizziness, and difficulty breathing. This medication might interact with other medications you're taking. Eptifibatide is cleared through the kidneys, so people having kidney diseases may get harmed.


If you have a history of bleeding disorders, recent surgeries, ulcers, or conditions that increase bleeding risk, caution is advised. Inform your healthcare provider immediately if you notice any signs of bleeding, such as unusual bruising, nosebleeds, or blood in your stool or urine. Individuals with a history of allergic reactions to eptifibatide or similar medications should exercise caution and inform their healthcare provider before starting treatment. If you have kidney problems, consult your your healthcare provider before starting this medication.

Side Effects

Eptifibatide may cause side effects, including an increased risk of bleeding, easy bruising, nausea, fever, headaches, and occasional dizziness.

Word Of Advice

You should tell your healthcare provider if you have had bleeding problems, kidney or liver issues, or allergic reactions to medications before. If you are planning surgery, tell your provider about this medication. Be cautious about medications you take, and don't drink too much alcohol while on this medication. Watch for signs of bleeding, like unusual bruising or blood in urine. Inform emergency responders that you are on this medication. Follow the prescribed dosage closely, and keep emergency contact details handy. If you are pregnant, breastfeeding, or taking other medicines, ask your provider for advice. 

Frequently Asked Question


  1. GlaxoSmithKline UK Limited,Electronic medicines compendium (EMC) [Revised on 21 May 2021] [Accessed on 18th Dec 2023],
  2. Kerstin Hogg and Jeffrey I. Weitz, Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs, Goodman and Gilman’s Pharmacological Basis of Therapeutics, 585-603
  3. Merck & Co.Inc.US Food and Drug Administration, [Revised on 2nd 2021] [Accessed on 18th August 2023], /


The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.