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EXEMESTANE

EXEMESTANE

Background and Date of approval EXEMESTANE

Exemestane is an anticancer medication that was approved for its medical use on 21st October 1999.

Uses of EXEMESTANE

Exemestane Tablet has been developed to treat early and advanced breast cancer in postmenopausal women who have taken Tamoxifen and other treatments before.

How is EXEMESTANE administered?

Exemestane is available as a tablet in a dose of 25mg. Take Exemestane Tablet once a day after food.

Side Effects of EXEMESTANE

The common side effects likely to occur while you are on the treatment with Exemestane Tablet are hot flashes, increased sweating, joint pain, tiredness, trouble sleeping, headache, increased appetite, and nausea. Call your healthcare provider if you experience allergic reactions or discomfort after taking this medicine.

Warnings

Exemestane Tablet is not recommended for women who have not attained menopause. Tell your doctor if you still get your periods. During the Exemestane Tablet treatment, your doctor may periodically monitor your bone mineral density and vitamin D levels to prevent serious complications. Report to your doctor if you have bone disorders (osteoporosis), heart problems, liver disease, or kidney problems.

Precautions

Exemestane Tablets may cause fertility problems in men and women. This Tablet is not recommended for pregnant women due to its ability to cause fetal harm. Inform your healthcare provider before starting this treatment if you are pregnant or planning to have a baby. Pregnancy testing is recommended for women of reproductive potential within at least 7 days before starting Exemestane treatment. Discuss with your physician about effective contraceptive methods to use during and for one month after the last dose of Exemestane. Do not breastfeed during treatment and for a month after the last dose of Exemestane Tablet.

Word of Advice

If you feel tired or weak, you should avoid driving or handling machines. Tell your physician before taking this medicine if you are taking any other prescription medications, over-the-counter drugs, or supplements.

Frequently Asked Questions

Q1.

How long does it take for Exemestane to lower estrogen?

It typically takes 2 to 3 days after the first dose for estrogen suppression to take place and the effect remains for about 4 to 5 days.

Q2.

Is it safe for men and women of reproductive age to use Exemestane Tablet?

Exemestane Tablet may cause fertility problems in men and women. This Tablet is not recommended for pregnant women due to its ability to cause fetal harm. Inform your healthcare provider before starting this treatment if you are pregnant or planning to have a baby.

Q3.

How will your physician monitor you while on treatment with Exemestane Tablet?

Your physician will monitor your bone health by checking your bone mineral density as Exemestane has the ability to reduce estrogen levels and increase the risk of fracture. Before prescribing the Exemestane tablet, your physician will check your blood vitamin D levels.

Q4.

Who should not take Exemestane Tablet?

Patients who are allergic to Exemestane or its ingredients should not take Exemestane Tablet. This medicine is not intended for women who have not attained menopause.

Q5.

What should you not take with Exemestane Tablet?

Exercise caution if you are taking medicines containing estrogen, hormone replacement therapy, birth control pills or patches. Tell your physician before taking Exemestane Tablet if you are taking any prescription medicines, vitamins or herbal supplements.

Q6.

Does Exemestane make your hair fall out?

Treatment with Exemestane might cause hair loss or thinning.

Q7.

How to store Exemestane Tablet?

Store Exemestane Tablet at room temperature, between 20°C to 25°C.

References

  1. Pharmacia & Upjohn Company LLC, [Revised on Nov 2021] [Accessed on 23rd Sep 2022], https://labeling.pfizer.com/ShowLabeling.aspx?id=523&section=PPI
  2. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.

Disclaimer

The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.

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