This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Factor IX is a coagulation factor that was approved for its medical use in 1997.
Mechanism of Action of undefined
Factor IX is a natural clotting factor synthesized by the liver to produce blood clotting. The clotting factors are essential to maintain hemostasis of blood i.e., to stop bleeding. Patients with Haemophilia B have a prolonged activated partial thromboplastin time (aPTT). Factor IX Injection increases the concentration of Factor IX in the plasma and works temporarily on behalf of the missing clotting factor IX to stop bleeding.
Uses of undefined
Factor IX Injection has been developed to treat Hemophilia B in adults and children. It is indicated to manage bleeding episodes after surgery and in patients diagnosed with congenital deficiency of Factor IX.
undefined Drug administaration and Dosage available
A healthcare professional will administer Factor IX injection as an intravenous infusion to the patients. The dosage and number of infusions to be administered typically depend on the individual’s response to the therapy. This injection is available as a lyophilized powder in the doses Factor IX 500IU injection and 600IU injection.
Warnings, Precautions and Side Effects of undefined
Contact your doctor immediately if you experience shortness of breath, fever, or any other discomfort while on treatment with Factor IX Injection. During the Factor IX injection treatment, your doctor may periodically monitor your blood cell counts, platelets, clotting time, blood sugar, electrolytes and kidney parameters to prevent serious complications. Report to your doctor if you have had a history of heart failure or liver problem. Tell your healthcare provider if you are about to undergo surgery or dental procedure while on treatment with Factor IX.
There is no evidence regarding the impact of Factor IX on pregnancy and breastfeeding. It is advisable to tell your healthcare provider before starting treatment with Factor IX Injection if you are pregnant, breastfeeding, or planning to have a baby.
The common side effects that are likely to occur while you are on the treatment with Factor IX Injection are fever, cough, nausea, injection site reaction, headache, dizziness, rash, blurred vision, drowsiness, vomiting, and flushing. If you experience symptoms such as breathing difficulty, chest tightness, wheezing, fast heartbeat, swelling of face, faintness, or hives, report to your doctor immediately.
Word Of Advice
Factor IX can make you feel dizzy, tired and make your vision blurry. Hence, you should avoid driving or handling machines while on this treatment. Apply cool compress at the injection site to reduce the pain.
Frequently Asked Question
1. Pfizer Inc., US Food & Drug Administration, [Revised on Apr 2021] [Accessed on 16th Sep 2022], https://www.fda.gov/media/73556/download
2. Orlova et al., Coagulation Factor IX for Hemophilia B Therapy, Acta Naturae, 2012, 4(13), 62-73, [Accessed on 16th Sep 2022], https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408704/pdf/AN20758251-13-062.pdf
The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.