FERRIC CITRATE

Written By:P. Thirumal ReddyB. Pharm Reviewed By:Dr. Tejashwin AdigaMBBS

Last updated on 31 Mar 2026 | 09:31 AM (IST)

FERRIC CITRATE

Background and Date of approval FERRIC CITRATE

Ferric citrate received FDA approval for treating hyperphosphatemia in adult patients with chronic kidney disease on dialysis on September 5, 2014.

Uses of FERRIC CITRATE

Ferric citrate is used in the treatment of iron deficiency anemia and hyperphosphatemia

How is FERRIC CITRATE administered?

Take the medication exactly as prescribed by your healthcare provider. The dosage and frequency will be determined based on your specific needs, the severity of your condition, and other factors. Ferric citrate is typically taken orally with water. Follow the instructions on whether to take it with or without food.

Side Effects of FERRIC CITRATE

The side effects known to occur commonly during the treatment with Ferric citrate are muscle, nausea, constipation, diarrhea, rashes, weight gain, change of taste, black stools, and fatigue.

Warnings

Ferric citrate carries important warnings that should be considered. These include the risk of allergic reactions and potential gastrointestinal side effects such as constipation or diarrhea. It can show interactions with other medications. This medication can cause problems in the liver and kidneys. The effectiveness of this medication in pediatric patients has not been established.

Precautions

Patients with preexisting liver, lung, kidney heart disease should tell their healthcare provider proper treatment. In such patients, regular monitoring of iron levels in the body is important. It is crucial to follow the guidance of healthcare professionals, report any concerning symptoms promptly, and be aware of the potential risks and benefits associated with ferric citrate use.

Word of Advice

Advice regarding ferric citrate is to consult a healthcare professional before starting or making any changes to your medication regimen. They can assess your medical history, evaluate potential risks and benefits, provide personalized guidance, and monitor your progress throughout treatment. Additionally, closely follow the instructions and recommendations your healthcare provider gives, report any unusual or concerning symptoms promptly, and communicate openly about any concerns or questions you may have. Pregnant and breastfeeding individuals should consult with healthcare professionals before using this medication. Your healthcare professional is the best resource for ensuring safe and effective medication use.

Frequently Asked Questions

Q1.

Can Ferric citrate be used in patients with kidney disease?

Ferric citrate may require dose adjustments in individuals with severe renal impairment. The medication is primarily excreted through the kidneys, and reduced kidney function can affect its clearance from the body. It is important to consult with a healthcare professional who can assess your renal function and determine the appropriate dosage or alternative treatment options if needed.

Q2.

How long does it take for ferric citrate to work?

The timeframe for ferric citrate to show its effects can vary depending on the individual and the underlying condition being treated. It may take several weeks of consistent use to see improvement in iron levels and associated symptoms. It is important to continue taking this medication as prescribed and to follow up with your healthcare provider for monitoring and evaluation.

Q3.

Can Ferric citrate cause stomach-related side effects?

Yes, gastrointestinal side effects such as nausea, vomiting, abdominal discomfort, and diarrhea can occur using Ferric citrate. If these side effects are persistent or bothersome, consult your healthcare provider, who can guide managing these symptoms or adjust the dosage if necessary.

Q4.

What should I do if I miss a dose of ferric citrate?

If you miss a dose of ferric citrate, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not double up on doses to make up for a missed dose.

Q5.

Can ferric citrate be used in children?

The safety and effectiveness of ferric citrate in pediatric patients have not been established. Its use in children should be done under the guidance of a healthcare professional who can evaluate the specific circumstances and determine the most appropriate treatment options.

References

Akebia Therapeutics, Inc., US Food & Drug Administration, [Revised on Mar 2021] [Accessed on 13th July 2023], https://fda.report/DailyMed/AADD18E0-3752-11E4-8510-0800200C9A66.pdf
Propak Health Ltd, European Medicine Agency, [Revised on Sept, 2015] [Accessed on 13th July 2021],https://www.ema.europa.eu/en/documents/product-information/fexeric-epar-product-information_en.pdf
J. Goddard, A.N. Turner, Kidney and Urinary Tract Disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 461-523.

Disclaimer

The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.

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