This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

The U.S. FDA approved fosaprepitant dimeglumine on 1/25/2008, It is used to prevent nausea and vomiting caused by chemotherapy (cancer treatment).

Mechanism of Action of undefined

Fosaprepitant dimeglumine injection blocks the action of a natural substance called neurokinin in the brain that causes nausea and vomiting.

Uses of undefined

Fosaprepitant dimeglumine treats bacterial infections (respiratory tract, urinary tract, nervous system, digestive system, and blood poisoning. It is effective only against bacterial infection and not against viral or fungal infection.

undefined Drug administaration and Dosage available

Fosaprepitant dimeglumine is available as an IV (intravenous) injection in the dose of  150 mg. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

Warnings, Precautions and Side Effects of undefined


Before taking this medication, you need to inform your doctor if you have liver disorders, allergic conditions, or other diseases. Indigestion, tiredness, headache, and loss of appetite are the common side effects of fosaprepitant dimeglumine injection.


Inform your doctor if you are allergic to fosaprepitant dimeglumine or any of the ingredients present in them or have kidney or muscle disorder. Inform your doctor about your prescribed and non-prescribed medicine and take a proper diet while under medication. It will be helpful for him to treat you based on your previous medical or make some dose adjustments.

Side Effects

The common side effects that are experienced while you are on the treatment with fosaprepitant dimeglumine are fatigue, Indigestion, constipation, loss of appetite, hiccups, headache. Consult your doctor immediately if you have skin blistering, peeling, rash, itching, difficulty breathing, or swallowing.

Word Of Advice

This injection should be administered only by the doctor or nurse and do not self administer this injection. Inform the doctor if the patient has any history of allergic reactions, liver, or kidney problems, and other medication taken for different medical conditions. Consult the doctor if the patient is planning for pregnancy or breastfeeding mother before taking this medication. Avoid driving and handling heavy machinery as it causes dizziness. Patients may feel a lack of concentration and alertness.

Frequently Asked Question


  1. KD Tripathi, Essentials of Medical Pharmacology, Antiemetic, Prokinetic and Digestant Drugs, 7th edition, 2013, 669-670.
  2. Merck Sharp & Dohme Corp, US Food and Drug Administration, [Revised date Feb 2016], [Accessed date 29th Nov 2021,
  3. .Merck Sharp & Dome BV, European Medicines Compendium (emc), [Revised date May 2021], [Accessed date 29th Nov 2021],


The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.