This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Gabapentin + nortriptyline is approved for medicinal use, to treat neuropathic pain (pain in damaged nerves).

Mechanism of Action of undefined

Gabapentin enhances the GABA derivative across the brain, enhances GABA action, and modulates the ca+ channel; both are involved in controlling neuronal excitability in the brain. Thereby, it helps to treat neuropathic pain.

Uses of undefined

It is used to treat neuropathic pain (pain in damaged nerves), epilepsy, peripheral neuropathic pain.

undefined Drug administaration and Dosage available

The medicine will be administered in the vein (intravenous) by the doctor. It is available as a 400mg tablet. Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.

Warnings, Precautions and Side Effects of undefined


Consult your doctor if you are allergic to Gabapentin or nortriptyline, any of the ingredients present in it. Inform your doctor immediately if you have Anaphylaxis or allergic reaction (serious, potentially life-threatening allergic reaction including difficulty breathing, swelling of the lips, throat, and tongue, and hypotension requiring emergency treatment).


Inform your doctor if you have a heart or kidney, persistent stomach pain, thyroid, diabetes, high blood pressure, or prostate problem before taking the medicine. Elderly patients with kidney disorders must inform their doctor of dosage adjustments to avoid undesirable effects. Consult your doctor if you are planning to get pregnant or think you may be pregnant or while you are breastfeeding.

Side Effects

Some of the common side effects of Gabapentin + nortriptyline Fever and chills, along with mouth or skin blisters, stomach ache, feeling drowsy, dizziness, lack of coordination, and tiredness, are also common symptoms. In addition, some individuals may experience low white blood cell counts, increased appetite, nervousness, blurred vision, double vision, vertigo, high blood pressure, or flushing. Other symptoms could involve difficulty breathing, bronchitis, sore throat, cough, dry nose, vomiting, nausea, stomach pain, joint pain, and swelling in the legs and arms. Report your doctor immediately, if you experience any allergic reactions such as difficulty breathing, chest tightness, rash, itching, hives, and swelling in the lips, tongue, or face, Fever and chills, along with mouth or skin blisters, stomach ache.

Word Of Advice

Talk to your doctor before going for a blood or urine test; Gabapentin + nortriptyline might interfere with the result of the patient. Inform your doctor if you have lactose intolerance or are allergic to any sugar. Forms. Consult your doctor if you have respiratory or nerve problems, and speak with him immediately if you have a severe skin reaction, persistent stomach pain, or breathing difficulty. The drug may alter your driving ability, so it is recommended to be safe and cautious if you need to drive.

Frequently Asked Question


  1. Glenmark Pharmaceuticals Europe Limited, Electronic medicines compendium (EMC), [Revised on  Jan 2023], [Accessed on 26th Sep 2023],
  2. Focus Pharmaceuticals Limited, Electronic medicines compendium (EMC), [Revised on n November 2021], [Accessed on 26th Sep 2023],
  3. Mallinckrodt Inc., US Food and Drug Administration (FDA),  [Accessed on 27th Sept 2023],
  4. Pfizer Inc., US Food and Drug Administration (FDA), [Revised on October 2017], [Accessed on 27th Sept 2023],
  5. KD Tripathi, Essentials of Medical Pharmacology, Drugs acting on central nervous system, 2019, 446-496, 486-496.


The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.