This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Ganciclovir contains the active ingredient Ganciclovir. This medicine is used to treat and prevent cytomegalovirus (CMV) infections. It is used to treat CMV infections in AIDS patients and prevent CMV infections in people who received an organ transplant from someone infected with this virus. Cytomegalovirus can affect anyone but is mainly seen in people with a weak immune system. It can affect any part of the body, including the retina at the back of the eye, causing eye problems. Ganciclovir received FDA approval on June 18, 1989, for treating cytomegalovirus (CMV) retinitis in immunocompromised individuals, including those with HIV.
Mechanism of Action of undefined
Ganciclovir is an antiviral medication that exerts its effect by inhibiting the replication of cytomegalovirus (CMV) in the body. By suppressing CMV viral activity, this medication helps to control CMV infections. It reduces the risk of disease progression, including vision loss.
Uses of undefined
Ganciclovir is used to treat and prevent cytomegalovirus (CMV) infection.
undefined Drug administaration and Dosage available
Ganciclovir can be consumed orally as capsules or administered intravenously (IV). The capsules are typically taken with water, with or without food, following the prescribed dosage and frequency for oral consumption. When administered intravenously, a healthcare professional delivers it via injection. The method of consumption depends on the specific formulation prescribed and should be followed as directed by a healthcare professional.
Warnings, Precautions and Side Effects of undefined
Ganciclovir carries warnings regarding potential bone marrow suppression, kidney toxicity, fertility impairment, mutagenic and carcinogenic potential, and the risk of birth defects. Additionally, it may cause hematologic toxicity, neurotoxicity, and ocular effects and can interact with other medications.
When using ganciclovir, precautions should be taken to minimize the risk of bone marrow suppression, kidney toxicity, and birth defects. Regular blood cell counts and kidney function monitoring is important, especially in individuals with pre-existing conditions. Effective contraception should be used during treatment. It should be used cautiously in individuals with neurological disorders, and ophthalmologic examinations are recommended for those receiving intravitreal implants.
Ganciclovir can cause various side effects. Common side effects may include nausea, vomiting, diarrhea, headache, fatigue, rash, elevated liver enzymes, and injection site reactions (with IV use). Serious side effects can include bone marrow suppression, kidney toxicity, neurotoxicity, and ocular effects.
Word Of Advice
If you are considering getting the Ganciclovir, it is important to be aware of the potential risks and warnings associated with the vaccine. Pregnancy and breastfeeding should be avoided while taking it. Effective contraception should be used during treatment. Use it cautiously if you have any pre-existing conditions such as liver disease, kidney disease, or eye disorder, as it may exacerbate them. Regular blood and eye examinations are recommended during treatment. Close monitoring and appropriate management are necessary in these cases. Adherence to these precautions and regular monitoring and communication with the healthcare provider can help ensure safe and effective use.
Frequently Asked Question
- KD Tripathi, Essentials of Medical Pharmacology, Antiviral drugs, 7th edition, 2013, 808.
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Antiviral agents (Non-retroviral), 12th edition, 2011, 1615.
- Gilead Sciences Ltd, Electronic medicines compendium (EMC), [ Revised on Jan 2021] [ Accessed on 18th May 2023], https://www.medicines.org.uk/emc/files/pil.2314.pdf
- Gilead Sciences, US Food, and Drug Administration, [ Revised on Feb 2020] [ Accessed on 18th May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/208464s008lbl.pdf
The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.